English
Related papers

Related papers: Towards a Conceptual Framework for Innate Immunity

200 papers

Model biomembrane systems play a crucial role in advancing biomedical research by providing simplified yet effective platforms for exploring complex biological mechanisms. These systems span a wide range of scales, from…

Soft Condensed Matter · Physics 2025-10-01 Ajit Seth , Sajal K. Ghosh , Veerendra K. Sharma

The reinforcement learning research area contains a wide range of methods for solving the problems of intelligent agent control. Despite the progress that has been made, the task of creating a highly autonomous agent is still a significant…

Machine Learning · Computer Science 2023-01-25 Artem Latyshev , Aleksandr I. Panov

The concept of innateness is rarely discussed in the context of artificial intelligence. When it is discussed, or hinted at, it is often the context of trying to reduce the amount of innate machinery in a given system. In this paper, I…

Artificial Intelligence · Computer Science 2018-01-18 Gary Marcus

The immune system is a real-time example of an evolving system that navigates the essentially infinite complexity of protein sequence space. How this system responds to disease and vaccination is discussed. Of particular focus is the case…

Cell Behavior · Quantitative Biology 2007-05-23 Michael W. Deem

Active systems across scales, ranging from molecular machines to human crowds, are usually modeled as assemblies of self-propelled particles driven by internally generated forces. However, these models often assume memoryless dynamics and…

Statistical Mechanics · Physics 2025-12-10 Marc Besse , Raphaël Voituriez

The Artificial Intelligence field is flooded with optimisation methods. In this paper, we change the focus to developing modelling methods with the aim of getting us closer to Artificial General Intelligence. To do so, we propose a novel…

Artificial Intelligence · Computer Science 2024-10-01 Alfredo Ibias , Guillem Ramirez-Miranda , Enric Guinovart , Eduard Alarcon

Seemingly since the inception of virtual humans, there has been an effort to make their behaviors more natural and human-like. In additions to improving movement's visual quality, there has been considerable research focused on creating…

Artificial Intelligence · Computer Science 2020-04-22 Weizi Li , Jan M. Allbeck

My overarching research goal is to provide robots with perceptional abilities that allow interactions with humans in a human-like manner. To develop these perceptional abilities, I believe that it is useful to study the principles of the…

Robotics · Computer Science 2021-09-02 Tobias Fischer

In this paper, after a telegraphic introduction to modern immunology, we present a simple model for the idiotypic network among antibodies and we study its relevance for the maintenance of immunological memory. We also consider the problem…

Condensed Matter · Physics 2008-02-03 Giorgio Parisi

Recent writings on "innate immune memory" or "trained immunity," and on "hormetic responses," herald reinvigoration of an important research area with early 20th century roots. However, it is questionable that the thesis of a "major…

Cell Behavior · Quantitative Biology 2018-07-24 Donald R. Forsdyke

Mathematical models are increasingly used in both academia and the pharmaceutical industry to understand how phenotypes emerge from systems of molecular interactions. However, their current construction as monolithic sets of equations…

Molecular Networks · Quantitative Biology 2007-10-19 Aneil Mallavarapu , Matthew Thomson , Benjamin Ullian , Jeremy Gunawardena

Compartmental epidemic models have been widely used for predicting the course of epidemics, from estimating the basic reproduction number to guiding intervention policies. Studies commonly acknowledge these models' assumptions but less…

Populations and Evolution · Quantitative Biology 2022-11-23 Alexander F. Siegenfeld , Pratyush K. Kollepara , Yaneer Bar-Yam

Revisiting the thirty years-old notions of resource-bounded immunity and simplicity, we investigate the structural characteristics of various immunity notions: strong immunity, almost immunity, and hyperimmunity as well as their…

Computational Complexity · Computer Science 2010-07-20 Tomoyuki Yamakami , Toshio Suzuki

The aim of this article is to address the question of the endogenization of mimetic processes in formal models of social systems. Starting from some studies about cognitive differences between humans and animals, we propose a formal…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 Chavalarias David , Bourgine Paul

The toxins associated with infectious diseases are potential targets for inhibitors which have the potential for prophylactic or therapeutic use. Many antibodies have been generated for this purpose, and the objective of this study was to…

Quantitative Methods · Quantitative Biology 2015-03-19 Alex Skvortsov , Peter Gray

One of the most important aims of the fields of robotics, artificial intelligence and artificial life is the design and construction of systems and machines as versatile and as reliable as living organisms at performing high level…

Artificial Intelligence · Computer Science 2014-12-24 Hector Zenil

In this paper we study the logical foundations of automated inductive theorem proving. To that aim we first develop a theoretical model that is centered around the difficulty of finding induction axioms which are sufficient for proving a…

Logic in Computer Science · Computer Science 2023-06-22 Stefan Hetzl , Tin Lok Wong

Artificial Immune Systems have been used successfully to build recommender systems for film databases. In this research, an attempt is made to extend this idea to web site recommendation. A collection of more than 1000 individuals web…

Neural and Evolutionary Computing · Computer Science 2010-07-05 Tom Morrison , Uwe Aickelin

The arrival of Large Language Models (LLMs) has stirred up philosophical debates about the possibility of realizing agency in an artificial manner. In this work we contribute to the debate by presenting a theoretical model that can be used…

Artificial Intelligence · Computer Science 2024-07-25 Maud van Lier , Gorka Muñoz-Gil

In this work, a conceptual bio-inspired parallel and distributed learning framework for the emergence of general intelligence is proposed, where agents evolve through environmental rewards and learn throughout their lifetime without…

Neural and Evolutionary Computing · Computer Science 2020-09-23 Sidney Pontes-Filho , Stefano Nichele