Mathematical model of immune response to hepatitis B
Populations and Evolution
2018-05-16 v1 Chaotic Dynamics
Abstract
A new detailed mathematical model for dynamics of immune response to hepatitis B is proposed, which takes into account contributions from innate and adaptive immune responses, as well as cytokines. Stability analysis of different steady states is performed to identify parameter regions where the model exhibits clearance of infection, maintenance of a chronic infection, or periodic oscillations. Effects of nucleoside analogues and interferon treatments are analysed, and the critical drug efficiency is determined.
Keywords
Cite
@article{arxiv.1805.05322,
title = {Mathematical model of immune response to hepatitis B},
author = {F. Fatehi Chenar and Y. N. Kyrychko and K. B. Blyuss},
journal= {arXiv preprint arXiv:1805.05322},
year = {2018}
}
Comments
24 pages, 10 figures