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Related papers: Towards a Conceptual Framework for Innate Immunity

200 papers

[Context & Motivation] Adaptive systems are an important research area. The dominant reason for adaptivity in systems are changes in the environment. Thus, it is an important question how to model the environment and how to determine the…

Software Engineering · Computer Science 2020-11-17 Fabian Kneer , Erik Kamsties , Klaus Schmid

A modeling formalism is proposed for the description and study of living and life-like systems. It provides an abstract conceptual model framework for real life and evolution of biological organisms. It is proposed, that this model…

Populations and Evolution · Quantitative Biology 2013-06-14 Margareta Segerståhl

The aim of this work is to try to bridge over theoretical immunology and disordered statistical mechanics. Our long term hope is to contribute to the development of a quantitative theoretical immunology from which practical applications may…

Disordered Systems and Neural Networks · Physics 2015-05-18 Adriano Barra , Elena Agliari

This paper describes necessary elements for constructing theoretical models of network and system administration. Armed with a theoretical model it becomes possible to determine best practices and optimal strategies in a way which…

Other Computer Science · Computer Science 2007-05-23 Mark Burgess

The adaptive immune system is a natural diagnostic and therapeutic. It recognizes threats earlier than clinical symptoms manifest and neutralizes antigen with exquisite specificity. Recognition specificity and broad reactivity is enabled…

Quantitative Methods · Quantitative Biology 2019-07-26 Alex J. Brown , Igor Snapkov , Rahmad Akbar , Milena Pavlović , Enkelejda Miho , Geir K. Sandve , Victor Greiff

Artificial intelligence (AI) is accelerating progress in modeling T and B cell receptors by enabling predictive and generative frameworks grounded in sequence data and immune context. This chapter surveys recent advances in the use of…

Biomolecules · Quantitative Biology 2026-01-30 Linhui Xie , Aurelien Pelissier , Yanjun Shao , Maria Rodriguez Martinez

The Human Immune System (HIS) works to protect a body from infection, illness, and disease. This system can inspire cybersecurity professionals to design an Artificial Immune System (AIS) based Intrusion Detection System (IDS). These…

Cryptography and Security · Computer Science 2022-08-17 William Anderson , Kaneesha Moore , Jesse Ables , Sudip Mittal , Shahram Rahimi , Ioana Banicescu , Maria Seale

The concept of intelligent system has emerged in information technology as a type of system derived from successful applications of artificial intelligence. The goal of this paper is to give a general description of an intelligent system,…

Computers and Society · Computer Science 2022-12-20 Martin Molina

Over the last decade, a new idea challenging the classical self-non-self viewpoint has become popular amongst immunologists. It is called the Danger Theory. In this conceptual paper, we look at this theory from the perspective of Artificial…

Neural and Evolutionary Computing · Computer Science 2010-07-05 Uwe Aickelin , Steve Cayzer

This review proposes an integrative framework grounded on interoception and embodied AI-termed the interoceptive machine framework-that translates biologically inspired principles of internal-state regulation into computational…

Artificial Intelligence · Computer Science 2026-04-28 Diego Candia-Rivera

In recent years computer systems have become increasingly complex and consequently the challenge of protecting these systems has become increasingly difficult. Various techniques have been implemented to counteract the misuse of computer…

Artificial Intelligence · Computer Science 2010-07-05 Julie Greensmith , Uwe Aickelin , Jamie Twycross

The study of immune system aging, i.e. immunosenescence, is a relatively new research topic. It deals with understanding the processes of immunodegradation that indicate signs of functionality loss possibly leading to death. Even though it…

Artificial Intelligence · Computer Science 2010-07-05 Grazziela P. Figueredo , Uwe Aickelin , Amanda Whitbrook

Artificial Intelligence systems are rapidly evolving, integrating extrinsic and intrinsic motivations. While these frameworks offer benefits, they risk misalignment at the algorithmic level while appearing superficially aligned with human…

Artificial Intelligence · Computer Science 2024-11-08 Joshua T. S. Hewson

Inner Interpretability is a promising emerging field tasked with uncovering the inner mechanisms of AI systems, though how to develop these mechanistic theories is still much debated. Moreover, recent critiques raise issues that question…

Artificial Intelligence · Computer Science 2024-08-01 Martina G. Vilas , Federico Adolfi , David Poeppel , Gemma Roig

Model immunization is an emerging direction that aims to mitigate the potential risk of misuse associated with open-sourced models and advancing adaptation methods. The idea is to make the released models' weights difficult to fine-tune on…

Computer Vision and Pattern Recognition · Computer Science 2024-12-23 Amber Yijia Zheng , Raymond A. Yeh

By linking conceptual theories with observed data, generative models can support reasoning in complex situations. They have come to play a central role both within and beyond statistics, providing the basis for power analysis in molecular…

Methodology · Statistics 2022-08-15 Kris Sankaran , Susan P. Holmes

Immunological systems have been an abundant inspiration to contemporary computer scientists. Problem solving strategies, stemming from known immune system phenomena, have been successfully applied to challenging problems of modern computing…

Cell Behavior · Quantitative Biology 2017-05-24 Alexandre de Castro , Carlos Frederico Fronza , Domingos Alves

One of the current AI issues depicted in popular culture is the fear of conscious super AIs that try to take control over humanity. And as computational power goes upwards and that turns more and more into a reality, understanding…

Neurons and Cognition · Quantitative Biology 2023-05-22 Daniel Lopes

Dendritic cells are the crime scene investigators of the human immune system. Their function is to correlate potentially anomalous invading entities with observed damage to the body. The detection of such invaders by dendritic cells results…

Artificial Intelligence · Computer Science 2010-07-05 Julie Greensmith , Uwe Aickelin

We review research papers which use game theory to model the decision making of individuals during an epidemic, attempting to classify the literature and identify the emerging trends in this field. We show that the literature can be…

Populations and Evolution · Quantitative Biology 2020-02-13 Sheryl L. Chang , Mahendra Piraveenan , Philippa Pattison , Mikhail Prokopenko