Related papers: Visualizing individual microtubules using bright-f…
A small depression is created in a straight optical fiber taper to form a local probe suitable for studying closely spaced, planar microphotonic devices. The tension of the "dimpled" taper controls the probe-sample interaction length and…
The fast-growing field of soft matter research requires increasingly sophisticated tools for experimental studies. One of the oldest and most widely used tools to study soft matter systems is optical microscopy. Recent advances in optical…
We present a method and model for the direct and continuous separation of red and white blood cells in plasma. The method is implemented at the microscale using a microfluidic system that consists of an array of integrated soft-magnetic…
We model analytically the dynamics of a cytoskeletal filament in a motility assay. The filament is described as rigid rod free to slide in two dimensions. The motor proteins consist of polymeric tails tethered to the plane and modeled as…
We present a direct experimental investigation of the optical field distribution around a suspended tapered optical nanofiber by means of a fluorescent scanning probe. Using a 100 nm diameter fluorescent bead as a probe of the field…
We analyze experimental observations of microtubules undergoing small fluctuations about a "balance point" when mixed in solution of two different kinesin motor proteins, KLP61F and Ncd. It has been proposed that the microtubule movement is…
Microtubules (MTs) represent basic components of a cytoskeleton. The present work studies nonlinear dynamics of MTs assuming tangential oscillations of the dimers. We introduce a two component model and show that the dynamics of MTs can be…
Brillouin Light Scattering is a powerful technique to measure the microwave excitations present in a magnetic system. In microfocused mode, the light is focused on the sample using a microscope objective. This accelerates substantially the…
This article presents an algorithm for the evaluation of organelles' movements inside of an unmodified live cell. We used a time-lapse image series obtained using wide-field bright-field photon transmission microscopy as an algorithm input.…
In-body communication is an upcoming field with significant implications for medical diagnostics and therapeutic interventions. Microbubbles have gained attention due to their distinct physical properties, making them promising candidates…
Single-molecule microscopy has become an indispensable tool for biochemical analysis. The capability of characterizing distinct properties of individual molecules without averaging has provided us with a different perspective for the…
We propose to use high numerical aperture single mode optical fibers like photonic crystal fiber for lensless in-line holographic microscopy. Highly divergent beam helps to overcome the spatial sampling limitation of the image sensor. In…
Microtubules are cytoskeletal filaments that play essential roles in many cellular processes and are key therapeutic targets in several diseases. Accurate segmentation of microtubule networks is critical for studying their organization and…
Different imaging modalities are used to extract the diverse information carried in an optical field. Two prominent modalities include bright field and phase contrast microscopy that can visualize the amplitude and phase features of a…
Noise plays a crucial role in the regulation of cellular and organismal function and behavior. Exploring noise's impact is key to understanding fundamental biological processes, such as gene expression, signal transduction, and the…
In this work, we use the standard deviation of image pixel intensity to analyse the speed, direction and surface-interaction of microparticles in fluid. First, we present an analytical model for estimating the total variance in the image…
We describe a novel application of atomic force microscopy (AFM) to directly visualize cytoskeletal fibers in human foreskin epithelial cells. The nonionic detergent Triton X-100 in a low concentration was used to remove the membrane,…
We use molecules to couple light into and out of microscale plasmonic waveguides. Energy transfer, mediated by surface plasmons, from donor molecules to acceptor molecules over ten micrometer distances is demonstrated. Also surface plasmon…
A novel beam profiler based on microstructured scintillation resin is presented. The detector consists of a bundle of waveguides, with an active area of 30 x 30 mm$^2$ and a pitch of 400 $\mu$m, obtained by molding a scintillating resin…
A novel device that can be used as a tunable support-free phase plate for transmission electron microscopy of weakly scattering specimens is described. The device relies on the generation of a controlled phase shift by the magnetic field of…