English
Related papers

Related papers: Visualizing individual microtubules using bright-f…

200 papers

Optical detection of individual nanometer-sized analytes, virus particles, and protein molecules holds great promise for understanding and control of biological samples and healthcare applications. As fluorescent labels impose restrictions…

Optics · Physics 2020-10-19 Martin Dieter Baaske , Peter Sebastian Neu , Michel Orrit

We report that M\"uller cells contain bundles of long specialized intermediate filaments about 10 nm in diameter; most likely, these filaments are the channels providing light transmission to photoreceptor cells in mammalian and avian…

Optics · Physics 2015-03-30 Vladimir Makarov , Lidia Zueva , Igor Khmelinskii , Mikhail Inyushin

This paper introduces a new method to perform signal processing using cells or atoms to synthesize variation in digital data stored in optical format. Interfacing small-scale biological or chemical systems with information stored on CD, DVD…

Chaotic Dynamics · Physics 2007-05-23 Cameron L. Jones

Fluorescence microscopy has revolutionized biomedical research over the past three decades. Its high molecular specificity and unrivaled single molecule level sensitivity have enabled breakthroughs in a variety of research fields. For in…

Optics · Physics 2012-03-21 Meng Cui , Ke Si , Reto Fiolka

Photonic molecules, named by analogy with chemical molecules, are clusters of closely located electromagnetically interacting microcavities or "photonic atoms". As two or several microcavities are brought close together, their optical modes…

Optics · Physics 2015-05-13 Svetlana V. Boriskina , Trevor M. Benson , Phillip Sewell

The optical elements comprised of sub-diffractive light scatterers, or metasurfaces, hold a promise to reduce the footprint and unfold new functionalities of optical devices. A particular interest is focused on metasurfaces for manipulation…

We propose a two-dimensional model for the organization of stabilized microtubules driven by molecular motors in an unconfined geometry. In this model two kinds of dynamics are competing. The first one is purely diffusive, with an…

Statistical Mechanics · Physics 2019-08-17 B. Bassetti , M. Cosentino Lagomarsino , P. Jona

Imaging single proteins has been a long-standing ambition for advancing various fields in natural science, as for instance structural biology, biophysics and molecular nanotechnology. In particular, revealing the distinct conformations of…

Super-resolution microscopy has catalyzed valuable insights into the sub-cellular, mechanistic details of many different biological processes across a wide range of cell types. Fluorescence polarization spectroscopy tools have also enabled…

Biological Physics · Physics 2023-01-25 Jack W Shepherd , Alex L Payne-Dwyer , Ji-Eun Lee , Aisha Syeda , Mark C Leake

Microbubbles - used as contrast agents in ultrasound imaging - are important tools in biomedical research, having been used together with ultrasound to develop significant diagnostic and therapeutic techniques. It has been suggested that…

Medical Physics · Physics 2022-11-23 Prashant Pandey

The circular polarization of light scattered by biological tissues provides valuable information and has been considered as a powerful tool for the diagnosis of tumor tissue. We propose a non-staining, non-invasive and in-vivo cancer…

We report on the 3-dimensional imaging of biological cells including living neurons by a recently developed fibered interferometric Scanning Optical Microscope. The topography and surface structure of mouse fibroblasts and hippocampal…

We employ heterodyne interferometry to investigate the effect of a single organic molecule on the phase of a propagating laser beam. We report on the first phase-contrast images of individual molecules and demonstrate a single-molecule…

Quantum Physics · Physics 2015-05-27 M. Pototschnig , Y. Chassagneux , J. Hwang , G. Zumofen , A. Renn , V. Sandoghdar

We present a method for determining the 3D intensity distribution of directed laser radiation with micrometer resolution in restricted volumes. Our method is based on in-coupling and guiding properties of optical fibers, with the current…

Optics · Physics 2013-02-14 Yevhen Miroshnychenko , Otto Nielsen , Aske Thorsen , Michael Drewsen

The use of individual multimode optical fibers in endoscopy applications has the potential to provide highly miniaturized and noninvasive probes for microscopy and optical micromanipulation. A few different strategies have been proposed…

Substrate engineering for steering cell growth is a wide and well-established area of research in the field of modern biotechnology. Here we introduce a micromachining technique to pattern an inert, transparent polymer matrix blended with a…

Label free tracking of small bio-particles such as proteins or viruses is of great utility in the study of biological processes, however such experiments are frequently hindered by weak signal strengths and a susceptibility to scattering…

Optics · Physics 2021-08-03 Joel Berk , Carl Paterson , Matthew R. Foreman

Optofluidic devices have revolutionized the manipulation and transportation of fluid at smaller length scales ranging from micrometers to millimeters. We describe a dedicated optical setup for studying laser-induced cavitation inside a…

Subwavelength imaging by microsphere lenses is a promising label-free super-resolution imaging technique. There is a growing interest to use live cells to replace the widely used non-biological microsphere lenses. In this work, we…

Optics · Physics 2021-07-06 Chunlei Jiang , Hangyu Yue , Bing Yan , Taiji Dong , Xiangyu Cui , Zengbo Wang

Significance: For the first time to our knowledge, a millifluidic device has been designed to observe the effects of blue-light irradiation in Pseudomonas aeruginosa PA01 bacterial biofilm. Approach: A bacterial biofilm is formed under…

Biological Physics · Physics 2023-11-30 Nidia Maldonado Carmona , Murielle Balthazar , Joanne L Fothergill , Nelly Henry