English
Related papers

Related papers: Analytically Solvable Asymptotic Model of Atrial E…

200 papers

Excitable membranes are an important type of nonlinear dynamical system and their study can be used to provide a connection between physical and biological circuits. We discuss two models of excitable membranes important in cardiac and…

Biological Physics · Physics 2012-12-18 Jarrett L. Lancaster , Esther M. Leise , Edward H. Hellen

We extend a non-Tikhonov asymptotic embedding, proposed earlier, for calculation of conduction velocity restitution curves in ionic models of cardiac excitability. Conduction velocity restitution is the simplest nontrivial spatially…

Tissues and Organs · Quantitative Biology 2010-02-12 R. D. Simitev , V. N. Biktashev

A recent method called Asymptotic Taylor expansion (ATEM) is applied to determine the analytical expression for eigenfunctions and numerical results for eigenvalues of the Schrodinger equation for the bistable potentials. Optimal…

Quantum Physics · Physics 2013-09-06 Okan Ozer , Halide Koklu , Serap Resitoglu

We consider a free interface problem which stems from a solid-gas model in combustion with pattern formation. We derive a third-order, fully nonlinear, self-consistent equation for the flame front. Asymptotic methods reveal that the…

Analysis of PDEs · Mathematics 2012-11-06 Claude-Michel Brauner , Lina Hu , Luca Lorenzi

In this study, we investigate the dynamics of moving fronts in three-dimensional spaces, which form as a result of in-situ combustion during oil production. This phenomenon is also observed in other contexts, such as various autowave models…

Analysis of PDEs · Mathematics 2025-02-05 Aleksei Liubavin , Mingkang Ni , Ye Zhang , Dmitrii Chaikovskii

An accurate closed-form solution is obtained to the SIR Epidemic Model through the use of Asymptotic Approximants (Barlow et. al, 2017, Q. Jl Mech. Appl. Math, 70 (1), 21-48). The solution is created by analytically continuing the divergent…

Populations and Evolution · Quantitative Biology 2021-01-05 Nathaniel S. Barlow , Steven J. Weinstein

For a particular case of three-body scattering in two dimensions, and matching analytical expressions at a transition point, we obtain accurate solutions for the hyperspherical adiabatic basis and potential. We find analytical expressions…

Quantum Physics · Physics 2020-08-05 Monique Lassaut , Alejandro Amaya-Tapia , Anthony D. Klemm , Sigurd Yves Larsen

We present a new approach for physics-based computational modeling of diseased human lungs. Our main object is the development of a model that takes the novel step of incorporating the dynamics of airway recruitment/de-recruitment into an…

Computational Engineering, Finance, and Science · Computer Science 2023-05-10 Carolin M. Geitner , Tobias Becher , Inéz Frerichs , Norbert Weiler , Jason H. T. Bates , Wolfgang A. Wall

Atrial fibrillation is a heart rhythm disorder that affects tens of millions people worldwide. The most effective treatment is catheter ablation. This involves irreversible heating of abnormal cardiac tissue facilitated by electroanatomical…

Medical Physics · Physics 2022-11-01 Jiyue He , Arkady Pertsov , Sanjay Dixit , Katie Walsh , Eric Toolan , Rahul Mangharam

Our evolving understanding of the heterocellular cardiac environment demands innovative tools for its study. While murine models are lauded for their versatility and accessibility, they are constrained by scale; tools designed for larger…

Biological Physics · Physics 2023-12-12 Gavin Tumlinson , Enaam Chleilat , Josef Madl , Peter Kohl , Viviane Timmermann

In [8], asymptotic expansion of the martingale with mixed normal limit was provided. The expansion formula is expressed by the adjoint of a random symbol with coefficients described by the Malliavin calculus, differently from the standard…

Probability · Mathematics 2012-12-27 Nakahiro Yoshida

This review focuses on the computerized modeling of the electrophysiology of the human atria, emphasizing the simulation of common arrhythmias such as atrial flutter (AFlut) and atrial fibrillation (AFib). Which components of the model are…

Computational Physics · Physics 2025-05-30 Olaf Dössel , Axel Loewe

Mathematical models of cardiac electrical excitation are increasingly complex, with multiscale models seeking to represent and bridge physiological behaviours across temporal and spatial scales. The increasing complexity of these models…

Tissues and Organs · Quantitative Biology 2016-12-13 Yen Ting Lin , Eugene TY Chang , Julie Eatock , Tobias Galla , Richard H Clayton

The mechanism of atrial fibrillation (AF) is poorly understood, resulting in disappointing success rates of ablative treatment. Different mechanisms defined largely by different atrial activation patterns have been proposed and, arguably,…

Tissues and Organs · Quantitative Biology 2020-01-27 Max Falkenberg , Andrew J. Ford , Anthony C. Li , Alberto Ciacci , Nicholas S. Peters , Kim Christensen

For a singularly perturbed system of reaction--diffusion equations, assuming that the 0th order solutions in regular and singular regions are all stable, we construct matched asymptotic expansions for formal solutions to any desired order…

patt-sol · Physics 2008-02-03 Xiao-Biao Lin

The field of analytic combinatorics, which studies the asymptotic behaviour of sequences through analytic properties of their generating functions, has led to the development of deep and powerful tools with applications across mathematics…

Combinatorics · Mathematics 2017-09-18 Stephen Melczer

We explore the feasibility of using fast-slow asymptotic to eliminate the computational stiffness of the discrete-state, continuous-time deterministic Markov chain models of ionic channels underlying cardiac excitability. We focus on a…

Pattern Formation and Solitons · Physics 2017-09-26 T. Stary , V. N. Biktashev

We consider estimation procedures which are recursive in the sense that each successive estimator is obtained from the previous one by a simple adjustment. The model considered in the paper is very general as we do not impose any…

Statistics Theory · Mathematics 2007-05-23 Teo Sharia

A new variational basis with well-behaved local approximation properties and multiple output is proposed for Coulomb systems. The trial function has proper behaviour at all Coulomb centres. Nonlinear asymptotic parameters are introduced…

Atomic Physics · Physics 2007-05-23 Vladimir S. Vanyashin

Recent research is revealing how cognitive processes are supported by a complex interplay between the brain and the rest of the body, which can be investigated by the analysis of physiological features such as breathing rhythms, heart rate,…

Quantitative Methods · Quantitative Biology 2023-03-10 Fernando E. Rosas , Diego Candia-Rivera , Andrea I Luppi , Yike Guo , Pedro A. M. Mediano