Fast-slow asymptotics for a Markov chain model of fast sodium current
Pattern Formation and Solitons
2017-09-26 v3
Abstract
We explore the feasibility of using fast-slow asymptotic to eliminate the computational stiffness of the discrete-state, continuous-time deterministic Markov chain models of ionic channels underlying cardiac excitability. We focus on a Markov chain model of the fast sodium current, and investigate its asymptotic behaviour with respect to small parameters identified in different ways.
Keywords
Cite
@article{arxiv.1703.09418,
title = {Fast-slow asymptotics for a Markov chain model of fast sodium current},
author = {T. Stary and V. N. Biktashev},
journal= {arXiv preprint arXiv:1703.09418},
year = {2017}
}
Comments
16 pages, 6 figures, as accepted to Chaos 2017/09/01