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Negative emotional responses to the daily life stresses have cumulative effects which, in turn, impose wide-ranging negative constraints on emotional well being and neurocognitive performance (Kalueff:2007cp, Charles:2013eq, Nadler:2010hk).…
The popularization of the internet created a revitalized digital media. With monetization driven by clicks, journalists have reprioritized their content for the highly competitive atmosphere of online news. The resulting negativity bias is…
Increasingly frequent publications in the literature report voice quality differences between depressed patients and controls. Here, we examine the possibility of using voice analysis as an early warning signal for the development of…
I present a theory of schizophrenia (SZ) that mechanistically explains its etiology, symptoms, pathophysiology, and treatment. SZ involves the chronic release of membrane polyunsaturated fatty acids (PUFAs) and their utilization for the…
Current diagnostic practice in psychiatry is not relying on objective biophysical evidence. Recent pandemic emphasized the need to address the rising number of mood disorders (in particular, depression) cases in a more efficient way. We are…
Alzheimer's disease is a human brain disease that affects a significant fraction of the population by causing problems with short-term memory, thinking, spatial orientation and behavior, memory loss and other intellectual abilities. Up to…
Uncontrolled, excessive production of pro-inflammatory mediators from immune cells and traumatized tissues can cause systemic inflammatory issues like sepsis, one of the ten leading causes of death in the United States and one of the three…
Adverse Childhood Experiences (ACEs) are defined as a collection of highly stressful, and potentially traumatic, events or circumstances that occur throughout childhood and/or adolescence. They have been shown to be associated with…
Substance abuse is the unrestrained and detrimental use of psychoactive chemical substances, unauthorized drugs, and alcohol. Continuous use of these substances can ultimately lead a human to disastrous consequences. As patients display a…
Depression is the leading cause of disability worldwide. Initial efforts to detect depression signals from social media posts have shown promising results. Given the high internal validity, results from such analyses are potentially…
Automation significantly alters human behavior, particularly risk-taking. Previous researches have paid limited attention to the underlying characteristics of automation and their mechanisms of influence on risk-taking. This study…
Elastic effects in a model of disordered nematic elastomers are numerically investigated in two dimensions. Networks crosslinked in the isotropic phase exhibit unusual soft mechanical response against stretching. It arises from gradual…
We discuss the possibility of multiple underlying etiologies of the condition currently labeled as schizophrenia. We support this hypothesis with a theoretical model of the prefrontal-limbic system. We show how the dynamical behavior of…
Sentiment analysis predicts the presence of positive or negative emotions in a text document. In this paper, we consider higher dimensional extensions of the sentiment concept, which represent a richer set of human emotions. Our approach…
Mental health is a global epidemic, affecting close to half a billion people worldwide. Chronic shortage of resources hamper detection and recovery of affected people. Effective sensing technologies can help fight the epidemic through early…
Deep reinforcement learning (DRL) algorithms have the potential to provide new insights into psychiatric disorders. Here we create a DRL model of schizophrenia: a complex psychotic disorder characterized by anhedonia, avoidance, temporal…
There is a surging concern regarding the adverse effects of light pollution on human well-being. This manuscript aims to emphasise the deleterious effects of uncontrolled night-light exposure on the health and mood of individuals residing…
Music, an integral part of our lives, which is not only a source of entertainment but plays an important role in mental well-being by impacting moods, emotions and other affective states. Music preferences and listening strategies have been…
Chronic pain is a widespread and debilitating condition that affects millions of individuals worldwide. Recent research has unveiled a connection between chronic pain and epigenetic processes, shedding light on the complex interplay between…
When developing new interventions to minimize the harmful effects of an exposure, investigators usually target the mechanisms that mediate the causal effect of the exposure on the outcome. Predicting the causal effect of these new…