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Stroke is a leading cause of disability and death worldwide, with ischemic strokes accounting for nearly 80% of cases. Fewer than 5% of patients receive the sole validated pharmacotherapy, intravenous thrombolysis, highlighting the urgent…

Neurons and Cognition · Quantitative Biology 2025-11-25 Sophie Béraud-Dufour , Ilona Legroux , Thierry Coppola , Patricia Lebrun , Nicolas Blondeau

Anxiety is the unease about a possible future negative outcome. In recent years, there has been growing interest in understanding how anxiety relates to our health, well-being, body, mind, and behaviour. This includes work on lexical…

Computation and Language · Computer Science 2026-02-24 Saif M. Mohammad

Causal effects are commonly defined as comparisons of the potential outcomes under treatment and control, but this definition is threatened by the possibility that the treatment or control condition is not well-defined, existing instead in…

Methodology · Statistics 2019-04-26 Raiden B. Hasegawa , Sameer K. Deshpande , Dylan S. Small , Paul R. Rosenbaum

Adenosine receptors are G-protein-coupled receptors involved in a wide range of physiological and pathological phenomena in most mammalian systems. All four receptors are widely expressed in the central nervous system, where they modulate…

Quantitative Methods · Quantitative Biology 2020-02-10 Vincent Huin , Claire-Marie Dhaenens , Mégane Homa , Kévin Carvalho , Luc Buée , Bernard Sablonnière

Humans dispose of two intertwined information processing pathways, cognitive information processing via neural firing patterns and diffusive volume control via neuromodulation. The cognitive information processing in the brain is…

Neurons and Cognition · Quantitative Biology 2011-12-07 Claudius Gros

Parkinson's disease (PD) is a neurodegenerative disorder characterized by increased response times leading to a variety of biomechanical symptoms such as tremors, stooping and gait instability. Although the deterioration in biomechanical…

Quantitative Methods · Quantitative Biology 2017-07-27 Vrutangkumar Shah , Sachin Goyal , Harish Palanthandalam-Madapusi

Although Vitamin D is believed to be involved in a large number of immune responses our understanding of these processes at cellular level remained at infancy. We develop and solve a coarse grained kinetic network model to quantify the…

Molecular Networks · Quantitative Biology 2013-04-29 Susmita Roy , Krishna Shrinivas , Biman Bagchi

There were over 70,000 drug overdose deaths in the USA in 2017. Almost half of those involved the use of Opioids such as Heroin. This research supports efforts to combat the Opioid Epidemic by further understanding factors that lead to…

Neural and Evolutionary Computing · Computer Science 2021-03-24 Sean-Kelly Palicki , R. Muhammad Atif Azad

Studies on intergenerational relationships between parents and children in Asian American families highlight their impact on mental health and well-being. This study investigates the role of ambivalent emotions in online narratives shared…

Computers and Society · Computer Science 2026-02-05 Sangpil Youm , Nari Yoo , Sou Hyun Jang

The primary tasks of a cognitive system is to survive and to maximize a life-long utility function, like the number of offsprings. A direct computational maximization of life-long utility is however not possible in complex environments,…

Neurons and Cognition · Quantitative Biology 2010-05-25 Claudius Gros

Because obesity is a risk factor for many serious illnesses such as diabetes, better understandings of obesity and eating disorders have been attracting attention in neurobiology, psychiatry, and neuroeconomics. This paper presents future…

Neurons and Cognition · Quantitative Biology 2011-11-29 Taiki Takahashi

Hypertension is one of the most common age-related chronic diseases and by predisposing individuals for heart failure, stroke and kidney disease, it is a major source of morbidity and mortality. Its etiology remains enigmatic despite…

Tissues and Organs · Quantitative Biology 2015-06-15 Klas H. Pettersen , Scott M. Bugenhagen , Javaid Nauman , Daniel A. Beard , Stig W. Omholt

Incubation with noradrenaline (norepinephrine) of isolated membranes of rat's brain corpus striatum and cortex, showed that ionic-magnesium (Mg2+) is required for the neurotransmitter activatory response of Adenylate Cyclase [ATP…

Other Quantitative Biology · Quantitative Biology 2010-12-16 Alfred Bennun

Bipolar Disorder is a chronic psychiatric illness characterized by pathological mood swings associated with severe disruptions in emotion regulation. Clinical monitoring of mood is key to the care of these dynamic and incapacitating mood…

Human-Computer Interaction · Computer Science 2018-06-29 Soheil Khorram , Mimansa Jaiswal , John Gideon , Melvin McInnis , Emily Mower Provost

This paper investigates the possibility of creating a machine learning tool that automatically determines the state of mind and emotion of an individual through a questionnaire, without the aid of a human expert. The state of mind and…

Machine Learning · Computer Science 2021-08-10 Rodrigo S. Jamisola

Emotion is an inherently subjective psychophysiological human-state and to produce an agreed-upon representation (gold standard) for continuous emotion requires a time-consuming and costly training procedure of multiple human annotators.…

Computer Vision and Pattern Recognition · Computer Science 2021-07-30 Alice Baird , Lukas Stappen , Lukas Christ , Lea Schumann , Eva-Maria Meßner , Björn W. Schuller

The use of multiple drugs accounts for almost 30% of all hospital admission and is the 5th leading cause of death in America. Since over 30% of all adverse drug events (ADEs) are thought to be caused by drug-drug interactions (DDI), better…

Quantitative Methods · Quantitative Biology 2020-09-02 Ricky Wang

In what capacity are affective augmentations helpful to humans, and what risks (if any) do they pose? In this position paper, we outline three works on affective augmentation systems, where our studies suggest these systems have the ability…

Human-Computer Interaction · Computer Science 2023-04-03 Abdallah El Ali

Emotions have been shown to play a role in argument convincingness, yet this aspect is underexplored in the natural language processing (NLP) community. Unlike prior studies that use static analyses, focus on a single text domain or…

Computation and Language · Computer Science 2025-07-22 Yanran Chen , Steffen Eger

In the last decades, the interest to understand the connection between brain and body has grown notably. For example, in psychoneuroimmunology many studies associate stress, arising from many different sources and situations, to changes in…

Quantitative Methods · Quantitative Biology 2022-07-27 Maria Elena Gonzalez Herrero , Christian Kuehn