Related papers: Statistical effects of dose deposition in track-st…
When irradiation is performed with gold nanoparticles (AuNPs), a different shape of cells in suspension or adherent to walls may result in different probability of cell survival. In a recent study, differences of up to a factor of 2 were…
Although there is an extensive statistical literature showing the disadvantages of discretizing continuous variables, categorization is a common practice in clinical research which results in substantial loss of information. A large…
We present a highly efficient molecular dynamics scheme for calculating the concentration depth profile of dopants in ion irradiated materials. The scheme incorporates several methods for reducing the computational overhead, plus a rare…
For efficient application of protons and light ions in radiotherapy, detailed knowledge and realistic models of the corresponding radiobiological mechanism are necessary. Basic characteristics of this mechanism have been represented within…
We find in experiments a linear dependence of ionization irradiation-induced degradations on pre-irradiation values of the input bias current in bipolar devices with simple input stages. The dependence is found to generally exist in all…
We study the optical properties of glass exposed to ionizing radiation, as it occurs in the space environment. 24 glass types have been considered, both space qualified and not space qualified. 72 samples (3 for each glass type) have been…
Radiative transfer coupled with highly realistic simulations of the solar atmosphere is routinely used to infer the physical properties underlying solar observations. Due to its computational efficiency, the method of short-characteristics…
Ion beams have been widely applied in a few biological research fields such as radioactive breeding, health protection, and tumor therapy. Up to now many interesting and impressive achievements in biology and agriculture have been made.…
Prediction models developed before the introduction of a new treatment may be used to estimate treatment effects of newly introduced treatments. One approach, known as model-based clinical evaluation in radiotherapy, does this by comparing…
The interaction of ultrashort, high intensity laser pulses with thin foil targets leads to ion acceleration on the target rear surface. To make this ion source useful for applications, it is important to optimize the transfer of energy from…
The radiation effects induced by Co60 serve as a reference system for the consideration of LET and RBE in normal and tumor tissue dose-effect relations are usually handled by the linear-quadratic model (LQ). This approximation excellently…
Applying the two-stage clonal expansion model to epidemiology of lung cancer among uranium miners, it has been revealed that radon acts as a promoting agent facilitating the clonal expansion of already mutated cells. Clonal expansion rate…
This study aims to analyse the effects of reducing Received Dose Intensity (RDI) in chemotherapy treatment for osteosarcoma patients on their survival by using a novel approach. In this scenario, toxic side effects are risk factors for…
At the Heidelberg Ion-Beam Therapy Center, the track structure of carbon ions of therapeutic energy after penetrating layers of simulated tissue was investigated for the first time. Measurements were conducted with carbon ion beams of…
We use long-term electron and proton in-situ measurements made by the CXD particle instruments, developed by Los Alamos National Laboratory and carried on board GPS satellites, to determine total ionizing dose (TID) values and daily/yearly…
The paper presents many facets of medical imaging investigations radiological risks. The total volume of prescribed medical investigations proves a serious lack in monitoring and tracking of the cumulative radiation doses in many health…
Accurately linking microscopic energy deposition from ionizing radiation to emergent biological outcomes remains a central challenge in radiobiological modelling, particularly when stochastic damage induction, cell-cycle dynamics, and…
Extensions have been made recently to the coronal approximation for the purpose of modelling line emission from carbon and oxygen in the lower solar atmosphere. The same modelling is used here for other elements routinely observed in the…
There are various sources of ionizing radiation exposure, where medical exposure for radiation therapy or diagnosis is the most common human-made source. Understanding how gene expression is modulated after ionizing radiation exposure and…
The accurate treatment of electronic effects in multi-million atom simulations of radiation-induced collision cascades is crucial for reliable predictions of primary radiation damage. In this work, we explore the performance of a recently…