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Observing the hybridisation kinetics of DNA probes immobilised on plasmonic nanoparticles is key in plamon enhanced fluorescence detection from weak emitting species, and refractive index based single-molecule detection on optoplasmonic…

We describe a simple model for the melting and optical properties of a DNA/gold nanoparticle aggregate. The optical properties at fixed wavelength change dramatically at the melting transition, which is found to be higher and narrower in…

Condensed Matter · Physics 2009-11-10 Sung Yong Park , D. Stroud

DNA regulation and repair processes require direct interactions between proteins and DNA at specific sites. Local fluctuations of the sugar-phosphate backbones and bases of DNA (a form of DNA "breathing") play a central role in such…

We explore the connections between the infrared and X-ray properties of AGNs. Using the well constrained infrared SEDs of a sample of local (i.e., z < 0.1) sample of X-ray AGNs, we develop new diagnostics that exploit 24um and 70um flux…

Cosmology and Nongalactic Astrophysics · Physics 2015-05-18 J. R. Mullaney , D. M. Alexander

We systematically study the fluorescence of low density Frenkel excitons in a crystal slab containing $N_T$ V-type three-level atoms. Based on symmetric quasi-spin realization of SU(3) in large $N$ limit, the two-mode exciton operators are…

Condensed Matter · Physics 2009-11-07 G. R. Jin , P. Zhang , Yu-xi Liu , C. P. Sun

This report investigates design enhancements of Fiber Optic Surface Plasmon Resonance (FO-SPR) biosensors with Gold and Silver metallic films. The effect of adding a Graphene coating on the sensitivity and detection accuracy of FO-SPR…

Applied Physics · Physics 2019-07-17 Mariam M. Moussilli , Abdul Rahman El Falou , Raed M. Shubair

We study the interaction of berberine and sanguinarine (plant alkaloids) with DNA in aqueous solutions, by using optical spectroscopy methods (absorption and fluorescence). The dependencies of alkaloid spectral characteristics on the…

Biological Physics · Physics 2012-01-16 V. G. Gumenyuk , N. V. Bashmakova , S. Yu. Kutovyy , V. M. Yashchuk , L. A. Zaika

By assuming that not only counter-ions but DNA molecules as well are thermally distributed according to a Boltzmann law, we propose a modified Poisson-Boltzmann equation at the classical level as starting point to compute the effects of…

Quantitative Methods · Quantitative Biology 2015-05-13 Alfredo Iorio , Samik Sen , Siddhartha Sen

Quenching effects in strong penguin matrix elements are investigated. A lattice determination of $\alpha_q^{NS}$, the constant that appears in the quenched ChPT relevant for the lattice analysis of $K\to\pi\pi$ matrix elements, shows that…

High Energy Physics - Lattice · Physics 2009-11-10 Jack Laiho

The Kirchhoff elastic theory of thin filaments with spontaneous curvature is employed in the understanding of the onset of the kink transitions observed in short DNA rings. Dynamical analysis shows that when its actual curvature is less…

Biological Physics · Physics 2009-10-31 Zhou Haijun , Ou-Yang Zhong-can

Real time laser induced fluorescence spectroscopy usage for microanalysis of DNA double helix defects is shown. The method is based on Forster resonance energy transfer (FRET) in intercalator-donor pair (acridine orange as a donor and…

Cesium lead halide nanocrystals and quantum dots are prominent materials for different types of applications because of their remarkable photophysical properties. However, they are also known to exhibit the same effects observed for…

By means of ab-initio calculations we investigate the optical properties of pure a-SiN$_x$ samples, with $x \in [0.4, 1.8]$, and samples embedding silicon nanoclusters (NCs) of diameter $0.5 \leq d \leq 1.0$ nm. In the pure samples the…

Mesoscale and Nanoscale Physics · Physics 2012-05-03 R. Guerra , M. Ippolito , S. Meloni , S. Ossicini

Multicolor excitation is at the core of many fluorescence spectroscopy techniques such as PIE-FRET, ALEX-FRET, or FCCS. However, the influence of the multiple laser excitations on the dye photophysics is often overlooked. Here, we show that…

Chemical Physics · Physics 2018-08-15 Mikhail Baibakov , Jérôme Wenger

We have developed an efficient numerical method to investigate light scattering from plasmonic nanospheres on a substrate covered by a shell, based on the half-space Greens function approach. We use this method to study optical scattering…

Mesoscale and Nanoscale Physics · Physics 2017-10-17 Huai-Yi Xie , Minfeng Chen , Yia-Chung Chang , Rakesh Singh Moirangthem

We report a comparison of two photonic techniques for single-molecule sensing: fluorescence nanoscopy and optoplasmonic sensing. As the test system, oligonucleotides with and without fluorescent labels are transiently hybridized to…

A theory is presented for the binding of small molecules such as surfactants to semiflexible polymers. The persistence length is assumed to be large compared to the monomer size but much smaller than the total chain length. Such polymers…

Soft Condensed Matter · Physics 2009-09-25 Haim Diamant , David Andelman

For an understanding of DNA elasticity at high mechanical loads (F > 30 pN), its helical nature needs to be taken into account, in the form of coupling between the twist and stretch degrees of freedom. The prevailing model for DNA…

Biological Physics · Physics 2016-06-29 Onno D. Broekmans , Graeme A. King , Greg J. Stephens , Gijs J. L. Wuite

Often only small amounts of sample are available for spectroscopic analytical determinations. This work investigates the enhancement of signal in columns packed with silica particles. We propose that silica particles cause the light to…

Optics · Physics 2024-11-20 Nathan A. Giauque , Callum E. Flowerday , Steven R. Goates

We study a complex formation between the DNA and cationic amphiphilic molecules. As the amphiphile is added to the solution containing DNA, a cooperative binding of surfactants to the DNA molecules is found. This binding transition occurs…

Condensed Matter · Physics 2009-10-31 P. S. Kuhn , Y. Levin , M. C. Barbosa
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