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Humans have $23$ pairs of homologous chromosomes. The homologous pairs are almost identical pairs of chromosomes. For the most part, differences in homologous chromosome occur at certain documented positions called single nucleotide…

Information Theory · Computer Science 2015-02-09 Govinda M. Kamath , Eren Şaşoğlu , David Tse

While much effort has focused on detecting positive and negative directional selection in the human genome, relatively little work has been devoted to balancing selection. This lack of attention is likely due to the paucity of sophisticated…

Populations and Evolution · Quantitative Biology 2013-07-17 Michael DeGiorgio , Kirk E. Lohmueller , Rasmus Nielsen

We give a detailed discussion of the matching of the BPS states of heterotic, type I and type I' theories in d=9 for general backgrounds. This allows us to explicitly identify these (composite) brane states in the type I' theory that lead…

High Energy Physics - Theory · Physics 2009-10-30 D. Matalliotakis , H. P. Nilles , S. Theisen

Repetitions within a given genealogical tree provides some information about the degree of consanguineity of a population. They can be analyzed with techniques usually employed in statistical physics when dealing with fixed point…

Statistical Mechanics · Physics 2009-10-31 Paolo De Los Rios , Oscar Pla

We consider a spatial model of the emergence of cooperation with synchronous births and deaths. Agents bear a tag and interact with their neighbors by playing the prisoner's dilemma game with strategies depending on their own and opponent's…

Populations and Evolution · Quantitative Biology 2020-05-04 Julien Flaig , Nicolas Houy

It has been suggested that the fundamental haploid-diploid cycle of eukaryotic sex exploits a rudimentary form of the Baldwin effect. This paper uses the well-known NKCS model to explore the effects of coevolution upon the behaviour of…

Populations and Evolution · Quantitative Biology 2019-03-19 Larry Bull

In the genomic era, the identification of gene signatures associated with disease is of significant interest. Such signatures are often used to predict clinical outcomes in new patients and aid clinical decision-making. However, recent…

Methodology · Statistics 2019-03-27 Naim U. Rashid , Quefeng Li , Jen Jen Yeh , Joseph G. Ibrahim

Sex determination in the order Hymenoptera is based on arrhenotoky, hymenopteran males are usually haploid and females diploid. Males of the Ichneumonidae Diadromus pulchellus, solitary endoparasitoid of A. assectella pupae are normally…

Populations and Evolution · Quantitative Biology 2016-08-16 Robert Kalmès , Danielle Rojas-Rousse

We study the evolution of allele frequencies in a large population where random mating is violated in a particular way that is related to recent works on speciation. Specifically, we consider non-random encounters in haploid organisms…

Populations and Evolution · Quantitative Biology 2013-09-05 David M. Schneider , Ayana B. Martins , Eduardo do Carmo , Marcus A. M. de Aguiar

We introduce a population dynamics model, where individual genomes are represented by bit-strings. Selection is described by death probabilities which depend on these genomes, and new individuals continuously replace the ones that die,…

Statistical Mechanics · Physics 2009-11-10 P. M. C. de Oliveira , J. S. Sa' Martins , D. Stauffer , S. Moss de Oliveira

In this paper the Penna model is reconsidered. With computer simulations we check how the control parameters of the model influence the size of the stable population.

Populations and Evolution · Quantitative Biology 2007-05-23 K. Malarz , M. Sitarz , P. Gronek , A. Dydejczyk

We model a social-encounter network where linked nodes match for reproduction in a manner depending probabilistically on each node`s attractiveness. The developed model reveals that increasing either the network`s mean degree or the…

Physics and Society · Physics 2017-06-22 S. Dipple , T. Jia , T. Caraco , G. Korniss , B. K. Szymanski

Sex chromosomes have evolved repeatedly across the Tree of Life, yet their evolutionary fates differ strikingly. In sharp contrast to mammals and birds with degenerated, stable Y/W chromosomes, in most amphibians, teleosts, non avian…

Populations and Evolution · Quantitative Biology 2026-03-24 Wen-Juan Ma , Ricard Fontserè , Tristan Cornelis , Paris Veltsos , Qi Zhou

Boolean networks may be viewed as idealizations of biological genetic networks, where each node is represented by an on-off switch which is a function of the binary output from some other nodes. We evolve connectivity in a single Boolean…

Biological Physics · Physics 2016-09-08 Stefan Bornholdt , Kim Sneppen

A bit-string model for the evolution of a population of haploid organisms, subject to competition, reproduction with mutation and selection is studied, using mean field theory and Monte Carlo simulations. We show that, depending on…

Statistical Mechanics · Physics 2009-11-07 Kathia M. Fehsenfeld , Ronald Dickman , Americo T. Bernardes

With the recent advances in DNA sequencing, it is now possible to have complete genomes of individuals sequenced and assembled. This rich and focused genotype information can be used to do different population-wide studies, now first time…

Data Structures and Algorithms · Computer Science 2011-09-08 Jouni Sirén , Niko Välimäki , Veli Mäkinen

We investigate through numerical simulations the effect of selection on two summary statistics for nucleotide variation in a sample of two genes from a population of N asexually reproducing haploid individuals. One is the mean time since…

Statistical Mechanics · Physics 2009-10-31 P. R. A. Campos , M. T. Sonoda , J. F. Fontanari

Genetic recombination can produce heterogeneous phylogenetic histories within a set of homologous genes. Delineating recombination events is important in the study of molecular evolution, as inference of such events provides a clearer…

Populations and Evolution · Quantitative Biology 2007-09-13 Cheong Xin Chan , Robert G. Beiko , Mark A. Ragan

We study a family of selection-mutation models of a sexual population structured by a phenotypical trait. The main feature of these models is the asymmetric trait heredity or fecundity between the parents : we assume that each individual…

Analysis of PDEs · Mathematics 2022-04-11 Benoît Perthame , Martin Strugarek , Cécile Taing

This article introduces a novel binary representation of the canonical genetic code based on both the structural similarities of the nucleotides, as well as the physicochemical properties of the encoded amino acids. Each of the four mRNA…

Biological Physics · Physics 2017-03-27 Louis R. Nemzer
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