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Accurate identification of haplotypes in sequenced human genomes can provide invaluable information about population demography and fine-scale correlations along the genome, thus empowering both population genomic and medical association…

Genomics · Quantitative Biology 2012-11-12 Fouad Zakharia , Carlos Bustamante

We propose a conformity-driven reproductive ability in which an individual $i$ is more (less) likely to imitate a neighbor $j$'s strategy if $j$'s strategy is majority (minority) in $i$'s neighborhood. The results on the evolutionary…

Physics and Society · Physics 2018-02-14 Han-Xin Yang , Lijun Tian

We investigate the scaling properties of the Penna model, which has become a popular tool for the study of population dynamics and evolutionary problems in recent years. We find that the model generates a normalised age distribution for…

Populations and Evolution · Quantitative Biology 2009-11-11 E. Brigatti , J. S. Sa' Martins , I. Roditi

Graph Neural Networks (GNNs) are widely used on a variety of graph-based machine learning tasks. For node-level tasks, GNNs have strong power to model the homophily property of graphs (i.e., connected nodes are more similar) while their…

Machine Learning · Computer Science 2022-04-26 Lun Du , Xiaozhou Shi , Qiang Fu , Xiaojun Ma , Hengyu Liu , Shi Han , Dongmei Zhang

Locating recombination hotspots in genomic data is an important but difficult task. Current methods frequently rely on estimating complicated models at high computational cost. In this paper we develop an extremely fast, scalable method for…

Applications · Statistics 2015-12-08 Jordan Rodu , Shane T. Jensen

We present a spectral study of the evolution matrix of the totally asymmetric exclusion process on a ring at half filling. The natural symmetries (translation, charge conjugation combined with reflection) predict only two fold degeneracies.…

Statistical Mechanics · Physics 2009-11-10 O. Golinelli , K. Mallick

We define a general class of models representing natural selection between two alleles. The population size and spatial structure are arbitrary, but fixed. Genetics can be haploid, diploid, or otherwise; reproduction can be asexual or…

Populations and Evolution · Quantitative Biology 2021-02-05 Benjamin Allen , Alex McAvoy

The reshaping and decorrelation of similar activity patterns by neuronal networks can enhance their discriminability, storage, and retrieval. How can such networks learn to decorrelate new complex patterns, as they arise in the olfactory…

Neurons and Cognition · Quantitative Biology 2015-06-04 Siu-Fai Chow , Stuart D. Wick , Hermann Riecke

The use of balanced crossover operators in Genetic Algorithms (GA) ensures that the binary strings generated as offsprings have the same Hamming weight of the parents, a constraint which is sought in certain discrete optimization problems.…

Neural and Evolutionary Computing · Computer Science 2020-04-24 Luca Manzoni , Luca Mariot , Eva Tuba

In this paper we study how different ways of combining character and word-level representations affect the quality of both final word and sentence representations. We provide strong empirical evidence that modeling characters improves the…

Computation and Language · Computer Science 2019-04-12 Jorge A. Balazs , Yutaka Matsuo

Phylogenetic networks are an extension of phylogenetic trees which are used to represent evolutionary histories in which reticulation events (such as recombination and hybridization) have occurred. A central question for such networks is…

Populations and Evolution · Quantitative Biology 2018-03-28 Andrew Francis , Vincent Moulton

We introduce and study an evolutionary complementarity game where in each round a player of population 1 is paired with a member of population 2. The game is symmetric, and each player tries to obtain an advantageous deal, but when one of…

Adaptation and Self-Organizing Systems · Physics 2015-06-26 Juergen Jost , Wei Li

As the amount and complexity of genetic information increases it is necessary that we explore some efficient ways of handling these data. This study takes the "divide and conquer" approach for analyzing high dimensional genomic data. Our…

Applications · Statistics 2013-08-15 Deniz Akdemir

We introduce homing vector automata, which are finite automata augmented by a vector that is multiplied at each step by a matrix determined by the current transition, and have to return the vector to its original setting in order to accept…

Formal Languages and Automata Theory · Computer Science 2017-08-01 Özlem Salehi , A. C. Cem Say , Flavio D'Alessandro

A simple model to encapsulate the essential growth properties of \emph{the web of human sexual contacts} is presented. In the model only heterosexual connection is considered and represented by a random growing bipartite graph where both…

Statistical Mechanics · Physics 2009-11-07 Guler Ergun

Motivated by research on gender identity norms and the distribution of the woman's share in a couple's total labor income, we consider functional additive regression models for probability density functions as responses with scalar…

Methodology · Statistics 2024-06-18 Eva-Maria Maier , Almond Stöcker , Bernd Fitzenberger , Sonja Greven

A probabilistic reconstruction of genealogies in a polyploid population (from 2x to 4x) is investigated, by considering genetic data analyzed as the probability of allele presence in a given genotype. Based on the likelihood of all possible…

Populations and Evolution · Quantitative Biology 2018-11-29 Frédéric Proïa , Fabien Panloup , Chiraz Trabelsi , Jérémy Clotault

This paper studies the haplotype assembly problem from an information theoretic perspective. A haplotype is a sequence of nucleotide bases on a chromosome, often conveniently represented by a binary string, that differ from the bases in the…

Information Theory · Computer Science 2014-05-13 Hongbo Si , Haris Vikalo , Sriram Vishwanath

Collaborative learning, which enables collaborative and decentralized training of deep neural networks at multiple institutions in a privacy-preserving manner, is rapidly emerging as a valuable technique in healthcare applications. However,…

Computer Vision and Pattern Recognition · Computer Science 2022-04-15 Liangqiong Qu , Niranjan Balachandar , Miao Zhang , Daniel Rubin

B-cell repertoires are characterized by a diverse set of receptors of distinct specificities generated through two processes of somatic diversification: V(D)J recombination and somatic hypermutations. B cell clonal families stem from the…

Populations and Evolution · Quantitative Biology 2024-03-19 Natanael Spisak , Gabriel Athènes , Thomas Dupic , Thierry Mora , Aleksandra M. Walczak