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We design and study splitting integrators for the temporal discretization of the stochastic FitzHugh--Nagumo system. This system is a model for signal propagation in nerve cells where the voltage variable is solution of a one-dimensional…

Numerical Analysis · Mathematics 2022-07-22 Charles-Edouard Bréhier , David Cohen , Giuseppe Giordano

The counter-intuitive phenomenon of coherence resonance describes a non-monotonic behavior of the regularity of noise-induced oscillations in the excitable regime, leading to an optimal response in terms of regularity of the excited…

Adaptation and Self-Organizing Systems · Physics 2021-03-24 Emre Baspinar , Leonhard Schülen , Simona Olmi , Anna Zakharova

Many multicellular communities propagate signals in a directed manner via excitable waves. Cell-to-cell heterogeneity is a ubiquitous feature of multicellular communities, but the effects of heterogeneity on wave propagation are still…

Biological Physics · Physics 2020-04-22 Xiaoling Zhai , Joseph W. Larkin , Gürol M. Süel , Andrew Mugler

Electro-cortical activity in patients with epilepsy may show abnormal rhythmic transients in response to stimulation. Even when using the same stimulation parameters in the same patient, wide variability in the duration of transient…

Neurons and Cognition · Quantitative Biology 2017-05-08 Gerold Baier , Peter N Taylor , Yujiang Wang

We identify a new type of pattern formation in spatially distributed active systems. We simulate one-dimensional two-component systems with predator-prey local interaction and pursuit-evasion taxis between the components. In a sufficiently…

Pattern Formation and Solitons · Physics 2013-05-29 V. N. Biktashev , M. A. Tsyganov

Whole-brain models offer a promising method of predicting seizure spread, which is critical for successful surgery treatment of focal epilepsy. Existing methods are largely based on structural connectome, which ignores the effects of…

Neurons and Cognition · Quantitative Biology 2022-07-13 Chen Wang , Sida Chen , Liang Huang , Lianchun Yu

In this paper, we address the exponential stabilization of the linearized FitzHugh-Nagumo system using an event-triggered boundary control strategy. Employing the backstepping method, we derive a feedback control law that updates based on…

Optimization and Control · Mathematics 2024-10-30 Víctor Hernández-Santamaría , Subrata Majumdar , Luz de Teresa

We study the interplay between diversity and noise in a 3D network of FitzHugh-Nagumo elements, with topology and dimensions chosen to model a pancreatic beta-cell cluster, as an example of an excitable cell network. Our results show that…

Biological Physics · Physics 2022-03-30 Stefano Scialla , Marco Patriarca , Els Heinsalu

In this work, a three-dimensional multicomponent reaction-diffusion model has been developed, combining excitable-system dynamics with diffusion processes and sharing conceptual features with the FitzHugh-Nagumo model. Designed to capture…

Machine Learning · Computer Science 2025-10-29 Anastasia-Maria Leventi-Peetz , Jörg-Volker Peetz , Kai Weber , Nikolaos Zacharis

We establish the existence and nonlinear stability of travelling wave solutions for a class of lattice differential equations (LDEs) that includes the discrete FitzHugh-Nagumo system with alternating scale-separated diffusion coefficients.…

Dynamical Systems · Mathematics 2018-08-03 W. M. Schouten , H. J. Hupkes

This paper is devoted to the numerical approximation of the spatially-extended FitzHugh-Nagumo transport equation with strong local interactions based on a particle method. In this regime, the time step can be subject to stability…

Numerical Analysis · Mathematics 2020-09-30 Joachim Crevat , Francis Filbet

In this paper, the authors study the distributed optimal control of a system of three evolutionary equations involving fractional powers of three selfadjoint, monotone, unbounded linear operators having compact resolvents. The system is a…

Optimization and Control · Mathematics 2019-07-25 Pierluigi Colli , Gianni Gilardi , Jürgen Sprekels

Emergence of noise induced regularity or Coherence Resonance in nonlinear excitable systems is well known. We explain theoretically why the normalized variance ($V_{N}$) of inter spike time intervals, which is a measure of regularity in…

Statistical Mechanics · Physics 2015-05-14 Santidan Biswas , Dibyendu Das , P. Parmananda , Anirban Sain

Previous work showed that the collective activity of large neuronal networks can be tamed to remain near its critical point by a feedback control that maximizes the temporal correlations of the mean-field fluctuations. Since such…

Neurons and Cognition · Quantitative Biology 2023-03-29 Juliane T. Moraes , Eyisto J. Aguilar Trejo , Sabrina Camargo , Silvio C. Ferreira , Dante R. Chialvo

The dynamics of spatiotemporal patterns in oscillatory reaction-diffusion systems subject to periodic forcing with a spatially random forcing amplitude field are investigated. Quenched disorder is studied using the resonantly forced complex…

Pattern Formation and Solitons · Physics 2009-10-31 C. J. Hemming , R. Kapral

Power systems usually go through electromagnetic and electromechanical transient processes after different disturbances. Learning the characteristics and the differences between them are important but not easy for students majoring in power…

Systems and Control · Electrical Eng. & Systems 2022-02-01 Abdulelah Alharbi , Shutang You

In this article, we study optimal control problems of spiking neurons whose dynamics are described by a phase model. We design minimum-power current stimuli (controls) that lead to targeted spiking times of neurons, where the cases with…

Dynamical Systems · Mathematics 2010-11-18 Isuru Dasanayake , Jr-Shin Li

Time modulation of the physical parameters offers interesting new possibilities for wave control. Examples include amplification of waves, harmonic generation and non-reciprocity, without resorting to non-linear mechanisms. Most of the…

Mathematical Physics · Physics 2025-07-25 Michaël Darche , Raphaël Assier , Sébastien Guenneau , Bruno Lombard , Marie Touboul

We study reaction-diffusion waves on curved two-dimensional surfaces, and determine the influence of curvature upon the nucleation and propagation of spatially localized waves in an excitable medium modelled by the generic FitzHugh-Nagumo…

Pattern Formation and Solitons · Physics 2014-08-13 Frederike Kneer , Eckehard Schöll , Markus A. Dahlem

We introduce and study a class of models of free fermions hopping between neighbouring sites with random Brownian amplitudes. These simple models describe stochastic, diffusive, quantum, unitary dynamics. We focus on periodic boundary…

Statistical Mechanics · Physics 2019-04-17 M. Bauer , D. Bernard , T. Jin
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