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In a weakly excitable medium, characterized by a large threshold stimulus, the free end of an isolated broken plane wave (wave tip) can either rotate (steadily or unsteadily) around a large excitable core, thereby producing a spiral…

Soft Condensed Matter · Physics 2009-10-31 Vincent Hakim , Alain Karma

We analyze the effect of weak-noise-induced transitions on the dynamics of the FitzHugh-Nagumo neuron model in a bistable state consisting of a stable fixed point and a stable unforced limit cycle. Bifurcation and slow-fast analysis give…

Dynamical Systems · Mathematics 2017-06-02 Marius E. Yamakou , Jürgen Jost

Transient dynamics is pervasive in the human brain and poses challenging problems both in mathematical tractability and clinical observability. We investigate statistical properties of transient cortical wave patterns with characteristic…

Pattern Formation and Solitons · Physics 2012-11-06 Markus A Dahlem , Thomas M Isele

We study the problem of initiation of excitation waves in the FitzHugh-Nagumo model. Our approach follows earlier works and is based on the idea of approximating the boundary between basins of attraction of propagating waves and of the…

Pattern Formation and Solitons · Physics 2017-09-26 B. Bezekci , V. N. Biktashev

Transmission through disordered samples can be controlled by illuminating a sample with waveforms corresponding to the eigenchannels of the transmission matrix. But can the TM be exploited to selectively excite quasi-normal modes and so…

Classical Physics · Physics 2018-11-21 Matthieu Davy , Azriel Z. Genack

Over one third of the estimated 3 million people with epilepsy in the US are medication resistant. Responsive neurostimulation from chronically implanted electrodes provides a promising treatment option and alternative to resective surgery.…

We report experimental observations of a controlled transition from a zonal-flow (ZF) dominated regime to a coexistence regime of ZFs and streamers, and finally to a streamer-dominated state in a linear magnetized plasma column. The…

Recently, a nonlinear stability theory has been developed for wave trains in reaction-diffusion systems relying on pure $L^\infty$-estimates. In the absence of localization of perturbations, it exploits diffusive decay caused by smoothing…

Analysis of PDEs · Mathematics 2024-10-24 Joannis Alexopoulos , Björn de Rijk

We analyse small parameters in selected models of biological excitability, including Hodgkin-Huxley (1952) model of nerve axon, Noble (1962) model of heart Purkinje fibres, and Courtemanche et al. (1998) model of human atrial cells. Some of…

Pattern Formation and Solitons · Physics 2009-11-11 I. V. Biktasheva , R. D. Simitev , R. Suckley , V. N. Biktashev

A fundamental challenge in physics is controlling the propagation of waves in disordered media despite strong scattering from inhomogeneities. Spatial light modulators enable one to synthesize (shape) the incident wavefront, optimizing the…

Optics · Physics 2017-02-15 Chia Wei Hsu , Seng Fatt Liew , Arthur Goetschy , Hui Cao , A. Douglas Stone

In sensory neurons the presence of noise can facilitate the detection of weak information-carrying signals, which are encoded and transmitted via correlated sequences of spikes. Here we investigate relative temporal order in spike sequences…

Neurons and Cognition · Quantitative Biology 2016-10-12 Jose A. Reinoso , M. C. Torrent , Cristina Masoller

We present a method to control the position as a function of time of one-dimensional traveling wave solutions to reaction-diffusion systems according to a pre-specified protocol of motion. Given this protocol, the control function is found…

Pattern Formation and Solitons · Physics 2014-05-22 Jakob Löber , Harald Engel

The influence of extreme external forcing on traveling-wave dynamics in an ensemble of weakly nonlocally coupled excitable FitzHugh--Nagumo systems is studied. Three types of external exposure are considered: periodic Gaussian pulses,…

Adaptation and Self-Organizing Systems · Physics 2026-05-12 N. I. Semenova , V. V. Semenov , A. V. Bukh

The FitzHugh-Nagumo model describing propagation of nerve impulses in axon is given by fast-slow reaction-diffusion equations, with dependence on a parameter $\epsilon$ representing the ratio of time scales. It is well known that for all…

Dynamical Systems · Mathematics 2016-09-12 Aleksander Czechowski , Piotr Zgliczyński

We investigate several control strategies for the transport of an excitation along a spin chain. We demonstrate that fast, high fidelity transport can be achieved using protocols designed with differentiable programming. Building on this,…

Quantum Physics · Physics 2022-11-30 Luuk Coopmans , Steve Campbell , Gabriele De Chiara , Anthony Kiely

The paper studies the excitability properties of a generalized FitzHugh-Nagumo model. The model differs from the purely competitive FitzHugh-Nagumo model in that it accounts for the effect of cooperative gating variables such as activation…

Dynamical Systems · Mathematics 2012-04-26 Alessio Franci , Guillaume Drion , Rodolphe Sepulchre

We investigate the impact of spatial-temporal discretisation schemes on the dynamics of a class of reaction-diffusion equations that includes the FitzHugh-Nagumo system. For the temporal discretisation we consider the family of six backward…

Dynamical Systems · Mathematics 2020-10-23 Willem M. Schouten-Straatman , Hermen Jan Hupkes

In this paper, we study the dynamic formation of transients when plane waves impinge on a dispersive slab that abruptly changes its electrical properties in time. The time-varying slab alternates between air and metal-like states, whose…

The slow dynamics of nearly stationary patterns in a FitzHugh-Nagumo model are studied using a phase dynamics approach. A Cross-Newell phase equation describing slow and weak modulations of periodic stationary solutions is derived. The…

Pattern Formation and Solitons · Physics 2009-10-31 Aric Hagberg , Ehud Meron , Thierry Passot

The Hodgkin-Huxley (HH) model is the currently accepted formalism of neuronal excitability. However, the HH model does not capture a number of biophysical behaviors associated with action potentials or propagating nerve impulses. Physical…

Neurons and Cognition · Quantitative Biology 2015-06-17 Jerel Mueller , William J. Tyler