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In two-dimensional reaction-diffusion systems, local curvature perturbations in the shape of traveling waves are typically damped out and disappear in the course of time. If, however, the inhibitor diffuses much faster than the activator,…

Pattern Formation and Solitons · Physics 2015-01-16 Sonja Molnos , Jakob Löber , Jan Frederik Totz , Harald Engel

An electronic circuit device, inspired on the FitzHugh-Nagumo model of neuronal excitability, was constructed and shown to operate with characteristics compatible with those of biological sensory neurons. The nonlinear dynamical model of…

We investigate a possibility of realization of structurally stable chaotic dynamics in neural systems. The considered model of interacting neurons consists of a pair of coupled FitzHugh-Nagumo systems, with the parameters being periodically…

Chaotic Dynamics · Physics 2017-03-07 Alexey Yu. Jalnine

We investigate diffusion-driven instabilities in a FitzHugh-Nagumo reaction-diffusion system with superdiffusive transport, modeled by fractional Laplacian operators with different diffusion orders for the activator and the inhibitor. A…

Pattern Formation and Solitons · Physics 2026-03-04 Rossella Rizzo , Gaetana Gambino , Vincenzo Sciacca , Marco Sammartino

The dynamics of activation waves in excitable media can give rise to spiral turbulence, the resulting spatiotemporal chaos being associated with empirical biological phenomena such as life-threatening disturbances in the natural rhythm of…

Chaotic Dynamics · Physics 2008-04-07 S. Sridhar , Sitabhra Sinha

The FitzHugh-Nagumo (FHN) model serves as a fundamental neuronal model which is extensively studied across various dynamical scenarios, we explore the dynamics of a scalar FHN oscillator under the influence of white noise. Unlike previous…

Disordered Systems and Neural Networks · Physics 2025-03-03 S. Hariharan , R. Suresh , V. K. Chandrasekar

Linearization around unstable travelling waves in excitable systems can be used to approximate strength-extent curves in the problem of initiation of excitation waves for a family of spatially confined perturbations to the rest state. This…

Pattern Formation and Solitons · Physics 2020-04-08 Christopher D. Marcotte , Vadim N. Biktashev

Motivated by recent experiments on intracellular calcium dynamics, we study the general issue of fluctuation-induced nucleation of waves in excitable media. We utilize a stochastic Fitzhugh-Nagumo model for this study, a spatially-extended…

Condensed Matter · Physics 2009-11-10 Herve Henry , Herbert Levine

We study the interplay between traveling action potentials and spatial inhomogeneities in the FitzHugh-Nagumo model to investigate possible mechanisms for the occurrence of fibrillatory states in the atria of the heart. Different dynamical…

Biological Physics · Physics 2010-04-07 Claudia Lenk , Mario Einax , Philipp Maass

Neurons are the central biological objects in understanding how the brain works. The famous Hodgkin-Huxley model, which describes how action potentials of a neuron are initiated and propagated, consists of four coupled nonlinear…

Neurons and Cognition · Quantitative Biology 2010-02-01 William Hanan , Dhagash Mehta , Guillaume Moroz , Sepanda Pouryahya

According to the conventional approach to model neural ensembles the extracellular environment has fixed ionic concentrations. However, in many cases the extracellular concentration of potassium ions can not be regarded as constant. That…

Disordered Systems and Neural Networks · Physics 2015-05-13 D. E. Postnov , F. Müller , R. B. Schuppner , L. Schimansky-Geier

Patterns and waves are basic and important phenomena that govern the dynamics of physical and biological systems. A common theme in investigating such systems is to identify the intrinsic factors responsible for such self-organization. The…

Analysis of PDEs · Mathematics 2018-06-25 Chao-Nien Chen , Y. S. Choi , Nicola Fusco

The stochastic FitzHugh-Nagumo model with time delayed-feedback is often studied in excitable regime to demonstrate the time-delayed control of coherence resonance. Here, we show that the impact of time-delayed feedback in the…

Adaptation and Self-Organizing Systems · Physics 2023-05-24 Vladimir V. Semenov , Andrei V. Bukh , Nadezhda Semenova

Excitable media are ubiquitous in nature, and in such systems the local excitation tends to self-organize in traveling waves, or in rotating spiral-shaped patterns in two or three spatial dimensions. Examples include waves during a pandemic…

Dynamical Systems · Mathematics 2023-12-25 Marie Cloet , Louise Arno , Desmond Kabus , Joeri Van der Veken , Alexander V. Panfilov , Hans Dierckx

We establish nonlinear stability of fronts that describe the creation of a periodic pattern through the invasion of an unstable state. Our results concern pushed fronts, that is, fronts whose propagation is driven by a localized mode at the…

Analysis of PDEs · Mathematics 2026-03-27 Montie Avery , Paul Carter , Björn de Rijk

The FitzHugh-Nagumo equation, which was derived as a simplification of the Hodgkin-Huxley model for nerve impulse propagation, has been extensively studied as a paradigmatic activator-inhibitor system. We consider the version of this system…

Dynamical Systems · Mathematics 2018-03-15 Paul Cornwell , Christopher K. R. T. Jones

The paper addresses the problem of parameter estimation (or identification) in dynamical networks composed of an arbitrary number of FitzHugh-Nagumo neuron models with diffusive couplings between each other. It is assumed that only the…

Systems and Control · Electrical Eng. & Systems 2025-02-25 Aleksandra Rybalko , Alexander Fradkov

In this article, we discuss the dynamics of the 3-dimensional FitzHugh-Rinzel (FHR) model and a class of non-homogeneous FitzHugh-Nagumo (Nh-FHN) Reaction-Diffusion systems. The Nh-FHN models can be used to generate relevant wave…

Pattern Formation and Solitons · Physics 2022-05-10 B. Ambrosio , M. A. Aziz-Alaoui , Argha Mondal , Arnab Mondal , Sanjeev K. Sharma , Ranjit K. Upadhyay

Waves in excitable media can be treated by a simple geometric theory. The propagation velocity is assumed known and evolution of wave fronts is determined by elementary physical principles (Fermat's principle, Huygens' principle). Based on…

Pattern Formation and Solitons · Physics 2007-05-23 Kristof Kaly-Kullai

The effect of a high-frequency signal on the FitzHugh-Nagumo excitable model is analyzed. We show that the firing rate is diminished as the ratio of the high-frequency amplitude to its frequency is increased. Moreover, it is demonstrated…

Statistical Mechanics · Physics 2016-08-16 David Cubero , José Pablo Baltanás , Jesús Casado-Pascual