Event-Triggered Control of Neuron Growth with Actuation at Soma
Abstract
We introduce a dynamic event-triggering mechanism for regulating the axonal growth of a neuron. We apply boundary actuation at the soma (the part of a neuron that contains the nucleus) and regulate the dynamics of tubulin concentration and axon length. The control law is formulated by applying a Zero-Order Hold (ZOH) to a continuous-time controller which guides the axon to reach the desired length. The proposed dynamic event-triggering mechanism determines the specific time instants at which control inputs are sampled from the continuous-time control law. We establish the existence of a minimum dwell-time between two triggering times that ensures avoidance of Zeno behavior. Through employing the Lyapunov analysis with PDE backstepping, we prove the local stability of the closed-loop system in -norm, initially for the target system, and subsequently for the original system. The effectiveness of the proposed method is showcased through numerical simulations.
Keywords
Cite
@article{arxiv.2310.00131,
title = {Event-Triggered Control of Neuron Growth with Actuation at Soma},
author = {Cenk Demir and Shumon Koga and Miroslav Krstic},
journal= {arXiv preprint arXiv:2310.00131},
year = {2024}
}
Comments
Accepted to American Control Conference 2024