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A Practical Fixed-Parameter Algorithm for Constructing Tree-Child Networks from Multiple Binary Trees

Discrete Mathematics 2019-07-22 v1 Combinatorics Populations and Evolution

Abstract

We present the first fixed-parameter algorithm for constructing a tree-child phylogenetic network that displays an arbitrary number of binary input trees and has the minimum number of reticulations among all such networks. The algorithm uses the recently introduced framework of cherry picking sequences and runs in O((8k)kpoly(n,t))O((8k)^k \mathrm{poly}(n, t)) time, where nn is the number of leaves of every tree, tt is the number of trees, and kk is the reticulation number of the constructed network. Moreover, we provide an efficient parallel implementation of the algorithm and show that it can deal with up to 100100 input trees on a standard desktop computer, thereby providing a major improvement over previous phylogenetic network construction methods.

Keywords

Cite

@article{arxiv.1907.08474,
  title  = {A Practical Fixed-Parameter Algorithm for Constructing Tree-Child Networks from Multiple Binary Trees},
  author = {Leo van Iersel and Remie Janssen and Mark Jones and Yukihiro Murakami and Norbert Zeh},
  journal= {arXiv preprint arXiv:1907.08474},
  year   = {2019}
}

Comments

Code available at https://github.com/nzeh/tree_child_code