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An electronic circuit device, inspired on the FitzHugh-Nagumo model of neuronal excitability, was constructed and shown to operate with characteristics compatible with those of biological sensory neurons. The nonlinear dynamical model of…

Neurons fire irregularly on multiple timescales when stimulated with a periodic pulse train. This raises two questions: Does this irregularity imply significant intrinsic stochasticity? Can existing neuron models be readily extended to…

细胞行为 · 定量生物学 2013-01-14 Daniel Soudry , Ron Meir

Periodic pulse train stimulation is generically used to study the function of the nervous system and to counteract disease-related neuronal activity, e.g., collective periodic neuronal oscillations. The efficient control of neuronal…

适应与自组织系统 · 物理学 2020-08-05 Kestutis Pyragas , Augustinas P. Fedaravičius , Tatjana Pyragienė

Despite intensive research, the mechanisms underlying how neurons encode external inputs remain poorly understood. Recent work has focused on the response of a single neuron to a weak, subthreshold periodic signal. By simulating the…

神经元与认知 · 定量生物学 2017-11-23 Maria Masoliver , Cristina Masoller

In this work we study the detection of weak stimuli by spiking neurons in the presence of certain level of noisy background neural activity. Our study has focused in the realistic assumption that the synapses in the network present…

神经元与认知 · 定量生物学 2009-06-04 Jorge F. Mejias , Joaquin J. Torres

We study the response of a Hodgkin-Huxley neuron stimulated by a periodic sequence of conductance pulses arriving through the synapse in the high frequency regime. In addition to the usual excitation threshold there is a smooth crossover…

生物物理 · 物理学 2010-04-08 L. S. Borkowski

A good understanding of how neurons use electrical pulses (i.e, spikes) to encode the signal information remains elusive. Analyzing spike sequences generated by individual neurons and by two coupled neurons (using the stochastic…

神经元与认知 · 定量生物学 2019-10-23 Maria Masoliver , Cristina Masoller

We characterize numerically the regime of anticipated synchronization in the coupled FitzHugh-Nagumo model for neurons. We consider two neurons, coupled unidirectionally (in a master-slave configuration), subject to the same random external…

凝聚态物理 · 物理学 2009-11-07 Raul Toral , C. Masoller , Claudio R. Mirasso , M. Ciszak , O. Calvo

We investigate the synchronization dynamics of two coupled noise-driven FitzHugh-Nagumo systems, representing two neural populations. For certain choices of the noise intensities and coupling strength, we find cooperative stochastic…

适应与自组织系统 · 物理学 2025-07-29 Philipp Hövel , Sarang A. Shah , Markus A. Dahlem , Eckehard Schöll

Dynamics of class II neurons, firing frequencies of which are strongly regulated by the inherent neuronal property, have been extensively studied since the formulation of the Hodgkin--Huxley model in 1952. However, how class II neurons…

无序系统与神经网络 · 物理学 2024-11-25 Naoki Masuda , Kazuyuki Aihara

A single neuron is known to generate almost identical spike trains when the same fluctuating input is repeatedly applied. Here, we study the reliability of spike firing in a pulse-coupled network of oscillator neurons receiving fluctuating…

适应与自组织系统 · 物理学 2015-05-13 Jun-nosuke Teramae , Tomoki Fukai

We discuss the synchronization of coupled neurons which are modelled as FitzHugh-Nagumo systems. As smallest entity in a larger network, we focus on two diffusively coupled subsystems, which can be interpreted as two mutually interacting…

混沌动力学 · 物理学 2008-09-05 Philipp Hoevel , Markus A. Dahlem , Eckehard Schoell

We consider the long-time behavior of a population of mean-field oscillators modeling the activity of interacting excitable neurons in large population. Each neuron is represented by its voltage and recovery variables, which are solution to…

概率论 · 数学 2019-06-24 Eric Luçon , Christophe Poquet

The response of a neural cell to an external stimulus can follow one of the two patterns: Nonresonant neurons monotonously relax to the resting state after excitation while resonant ones show subthreshold oscillations. We investigate how do…

神经元与认知 · 定量生物学 2009-11-10 T. Verechtchaguina , L. Schimansky-Geier , I. M. Sokolov

In this paper, we study an excitable, biophysical system that supports wave propagation of nerve impulses. We consider a slow-fast, FitzHugh-Rinzel neuron model where only the membrane voltage interacts diffusively, giving rise to the…

混沌动力学 · 物理学 2021-11-03 A. Mondal , A. Mondal , S. Kumar Sharma , R. Kumar Upadhyay , C. G. Antonopoulos

In this report trial-to-trial variations in the synchronized responses of neural networks are offered as evidence for excitation-inhibition ratio being a dynamic variable over time scales of minutes. Synchronized network responses to…

神经元与认知 · 定量生物学 2015-01-05 Netta Haroush , Shimon Marom

We study patterns of partial synchronization in a network of FitzHugh-Nagumo oscillators with empirical structural connectivity measured in human subjects. We report the spontaneous occurrence of synchronization phenomena that closely…

适应与自组织系统 · 物理学 2021-02-03 M. Gerster , R. Berner , J. Sawicki , A. Zakharova , A. Škoch , J. Hlinka , K. Lehnertz , E. Schöll

We address a question on the effect of common stochastic inputs on the correlation of the spikes trains of two neurons when they are possibly nonidentical and are coupled through direct connections. We show that the change in the…

神经元与认知 · 定量生物学 2013-04-24 E. Bolhasani , Y. Azizi , A. Valizadeh

Many systems are modulated by unknown slow processes. This hinders analysis in highly non-linear systems, such as excitable systems. We show that for such systems, if the input matches the sparse `spiky' nature of the output, the spiking…

神经元与认知 · 定量生物学 2014-05-01 Daniel Soudry , Ron Meir

We study the statistical physics of a surprising phenomenon arising in large networks of excitable elements in response to noise: while at low noise, solutions remain in the vicinity of the resting state and large-noise solutions show…

适应与自组织系统 · 物理学 2020-04-01 Jonathan D. Touboul , Charlotte Piette , Laurent Venance , G. Bard Ermentrout
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