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Biological tissues are composed of discrete compartments of biochemical media that often exhibit subtle differences in refractive index. Light propagating through these compartments partially diffracts in a forward direction with a pi/2…

光学 · 物理学 2025-05-12 Gregory N. McKay , Jerome Mertz , Nicholas J. Durr

Evaporation of blood droplets and diluted blood samples is a topic of intensive research, as it is seen as a possible low-cost tool for diagnosis. So far, samples with volume fraction down to a few percents of Red Blood Cells (RBCs) have…

Due to the highly inhomogeneous distributions of refractive indexes, light propagation in complex media such as biological tissue experiences multiple light scattering events. The suppression and control of multiple light scattering events…

We describe a technique to measure the position of a dipolar scatterer based on self-homodyne detection of the scattered light. The method can theoretically reach the Heisenberg limit, at which information gained about the position is…

光学 · 物理学 2021-12-01 G. Cerchiari , L. Dania , D. S. Bykov , R. Blatt , T. Northup

Developing advanced technologies for sensing and imaging biological samples is crucial for medical applications, making quantum-enhanced methods particularly valuable, as they promise significant benefits over classical techniques. An…

量子物理 · 物理学 2025-08-21 Cristofero Oglialoro , Enno Giese

The signal registered by a plane photodetector placed behind an optically inhomogeneous object irradiated by two coherent Gaussian beams intersecting inside the object at small angle to each other is calculated in the single-scattering…

光学 · 物理学 2018-05-23 G. G. Kozlov

We present an optical wavefront shaping approach that allows tracking and localization of signal hidden inside or behind a scattering medium. The method combines traditional feedback based wavefront shaping together with a switch function,…

Glucometers present an important self-monitoring tool for diabetes patients and therefore must exhibit high accu- racy as well as good usability features. Based on an invasive, photometric measurement principle that drastically reduces the…

应用统计 · 统计学 2016-02-11 Nevine Demitri , Abdelhak M. Zoubir

We propose methods that use specular, multibounce lidar returns to detect and map specular surfaces that might be invisible to conventional lidar systems that rely on direct, single-scatter returns. We derive expressions that relate the…

计算机视觉与模式识别 · 计算机科学 2023-02-22 Connor Henley , Siddharth Somasundaram , Joseph Hollmann , Ramesh Raskar

We developed a 12-liter volume neutron detector filled with the liquid scintillator EJ301 that measures neutrons in an underground laboratory where dark matter and neutrino experiments are located. The detector target is a cylindrical…

仪器与探测器 · 物理学 2015-06-15 C. Zhang , D. -M. Mei , P. Davis , B. Woltman , F. Gray

The detection of VUV scintillation light, e.g. in (liquid) argon detectors, commonly includes a reflector with a fluorescent coating, converting UV photons to visible light. The light yield of these detectors depends directly on the…

仪器与探测器 · 物理学 2015-12-16 Laura Baudis , Giovanni Benato , Rugard Dressler , Francesco Piastra , Ilya Usoltsev , Manuel Walter

A novel concept for the detection of tau neutrinos is presented, potentially suitable for use in a long-baseline neutrino oscillation experiment. It relies on the direct identification of the tau leptons produced in charged-current…

高能物理 - 实验 · 物理学 2010-02-03 Roger Forty

Detecting the carrier scattering mechanisms in a materials system is important for transport related science and engineering. The approaches of fast laser process and electrical conductivity matching were used in previous literature, which…

材料科学 · 物理学 2014-10-21 Shuang Tang , Mildred S. Dresselhaus

Diabetic retinopathy is one of the most threatening complications of diabetes that leads to permanent blindness if left untreated. One of the essential challenges is early detection, which is very important for treatment success.…

机器学习 · 计算机科学 2020-03-06 Borys Tymchenko , Philip Marchenko , Dmitry Spodarets

We present the characterization of a novel radiation detector based on an opaque water-based liquid scintillator. Opaque scintillators, also known as LiquidO, are made to be highly scattering, such that the scintillation light is…

仪器与探测器 · 物理学 2024-11-21 LiquidO Collaboration

IR absorption spectroscopy of hemoglobin was performed using an IR optical parametric oscillator laser and a commercial atomic force microscope in a novel experimental arrangement based on the use of a bottom-up excitation alignment. This…

生物物理 · 物理学 2010-10-29 Fiona Yarrow , James H. Rice

Bioluminescence detection requires single-photon sensitivity, extremely low detection limits and wide dynamic range. Such performances were traditionally assured by photomultiplier-tubes based systems. However, development of novel…

仪器与探测器 · 物理学 2020-08-26 S. Lomazzi , M. Caccia , C. Distasi , M. Dionisi , D. Lim , A. Martemiyanov , L. Nardo , F. A. Ruffinatti , R. Santoro

In an experiment with a 65 MeV/nucleon polarized deuteron beam on a liquid-deuterium target at KVI, several multi-body final states in deuteron-deuteron scattering were identified. For these measurements, a unique and advanced detection…

Integrating optical diffraction tomography with imaging flow cytometry enables label-free quantifications of the three-dimensional (3D) morphology and hemoglobin content of red blood cells (RBCs) in their natural form. Self-rotation of RBCs…

医学物理 · 物理学 2023-09-28 Yu-Hsiang Chang , Yang-Hsien Lin , Kung-Bin Sung

Neutron Compton scattering measurements have the potential to provide direct information about atomic momentum distributions and adiabatic energy surfaces in condensed matter. First applied to measuring the condensate fraction in superfluid…

凝聚态物理 · 物理学 2007-05-23 Greg Watson