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This paper explores the use of a soft ground-truth mask ("soft mask'') to train a Fully Convolutional Neural Network (FCNN) for segmentation of Multiple Sclerosis (MS) lesions. Detection and segmentation of MS lesions is a complex task…

计算机视觉与模式识别 · 计算机科学 2019-01-29 Eytan Kats , Jacob Goldberger , Hayit Greenspan

Objective: A method to predict the relationships between decompressed volume of orbital soft tissues, backward displacement of globe after osteotomy, and force exerted by the surgeon, was proposed to improve surgery planning in exophthalmia…

Detecting and classifying cells in histopathology H\&E stained whole-slide images is a core task in computational pathology, as it provides valuable insight into the tumor microenvironment. In this work we investigate the impact of ground…

图像与视频处理 · 电气工程与系统科学 2023-12-20 Lydia A. Schoenpflug , Viktor H. Koelzer

Hard-magnetic soft materials (HMSMs) are particulate composites that consist of a soft matrix embedded with particles of high remnant magnetic induction. Since the application of an external magnetic flux induces a body couple in HMSMs, the…

数值分析 · 数学 2023-01-05 Farzam Dadgar-Rad , Mokarram Hossain

Segmentations are crucial in medical imaging to obtain morphological, volumetric, and radiomics biomarkers. Manual segmentation is accurate but not feasible in the radiologist's clinical workflow, while automatic segmentation generally…

Recent studies have shown that Machine Learning (ML) models can exhibit bias in real-world scenarios, posing significant challenges in ethically sensitive domains such as healthcare. Such bias can negatively affect model fairness, model…

机器学习 · 计算机科学 2025-09-05 Junyu Yan , Feng Chen , Yuyang Xue , Yuning Du , Konstantinos Vilouras , Sotirios A. Tsaftaris , Steven McDonagh

This paper presents simulations of the impact of tongue surgery on tongue movements and on speech articulation. For this, a 3D biomechanical Finite Element (FE) model of the tongue is used. Muscles are represented within the FE structure by…

医学物理 · 物理学 2007-10-16 Stéphanie Buchaillard , Muriel Brix , Pascal Perrier , Yohan Payan

Complex computer codes, for instance simulating physical phenomena, are often too time expensive to be directly used to perform uncertainty, sensitivity, optimization and robustness analyses. A widely accepted method to circumvent this…

数值分析 · 数学 2011-04-22 Bertrand Iooss , Loïc Boussouf , Vincent Feuillard , Amandine Marrel

Clinical diffusion imaging requires short acquisition times and good image quality to permit its use in various medical applications. In turn, these demands require the development of a robust and efficient post-processing framework in…

医学物理 · 物理学 2015-02-18 Ivan I. Maximov , Farida Grinberg , Irene Neuner , N. Jon Shah

This document gives guidelines to set up, run, and postprocess correct simulations with the finite element method. It is not an introduction to the method itself, but rather a list of things to check and possible mistakes to watch out for…

数值分析 · 计算机科学 2018-11-15 Martin Bäker

Mammography is currently the primary imaging modality for breast cancer screening and plays an important role in cancer diagnostics. A standard mammographic image acquisition always includes the compression of the breast prior x-ray…

Computational biomechanics of the brain for neurosurgery is an emerging area of research recently gaining in importance and practical applications. This review paper presents the contributions of the Intelligent Systems for Medicine…

计算工程、金融与科学 · 计算机科学 2019-04-03 K. Miller , G. R. Joldes , G. Bourantas , S. K. Warfield , D. E. Hyde , R. Kikinis , A. Wittek

Errors in biomechanics simulations arise from modeling and discretization. Modeling errors are due to the choice of the mathematical model whilst discretization errors measure the impact of the choice of the numerical method on the accuracy…

While micro-CT systems are instrumental in preclinical research, clinical micro-CT imaging has long been desired with cochlear implantation as a primary example. The structural details of the cochlear implant and the temporal bone require a…

High-fidelity semantic segmentation of magnetic resonance volumes is critical for estimating tissue morphometry and relaxation parameters in both clinical and research applications. While manual segmentation is accepted as the…

图像与视频处理 · 电气工程与系统科学 2019-02-07 Arjun D. Desai , Garry E. Gold , Brian A. Hargreaves , Akshay S. Chaudhari

A computer simulation has to be fast to be helpful, if it is employed to study the behavior of a multicomponent dynamic system. This paper discusses modeling concepts and algorithmic techniques useful for creating such fast simulations.…

数据结构与算法 · 计算机科学 2007-05-23 Boris D. Lubachevsky

Statistical shape analysis of slabular objects like groups of hippocampi is highly useful for medical researchers as it can be useful for diagnoses and understanding diseases. This work proposes a novel object representation based on…

统计方法学 · 统计学 2024-09-09 Mohsen Taheri , Stephen M. Pizer , Jörn Schulz

Living soft tissues appear to promote the development and maintenance of a preferred mechanical state within a defined tolerance around a so-called set-point. This phenomenon is often referred to as mechanical homeostasis. In contradiction…

计算工程、金融与科学 · 计算机科学 2021-09-23 Jonas F. Eichinger , Maximilian J. Grill , Iman Davoodi Kermani , Roland C. Aydin , Wolfgang A. Wall , Jay D. Humphrey , Christian J. Cyron

Surface-based cortical analysis is valuable for a variety of neuroimaging tasks, such as spatial normalization, parcellation, and gray matter (GM) thickness estimation. However, most tools for estimating cortical surfaces work exclusively…

Tuning the regularization hyperparameter $\alpha$ in inverse problems has been a longstanding problem. This is particularly true in the case of fetal brain magnetic resonance imaging, where an isotropic high-resolution volume is…

图像与视频处理 · 电气工程与系统科学 2023-04-06 Priscille de Dumast , Thomas Sanchez , Hélène Lajous , Meritxell Bach Cuadra