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We study the energy deposition by light and heavy nuclei in tissue-like media as used for cancer therapy. The depth-dose distributions for protons, $^{3}$He, $^{12}$C, $^{20}$Ne, and $^{58}$Ni nuclei are calculated within a Monte Carlo…

医学物理 · 物理学 2010-11-03 Igor Pshenichnov , Igor Mishustin , Walter Greiner

We study the propagation of nucleons and nuclei in tissue-like media within a Monte Carlo Model for Heavy-ion Therapy (MCHIT) based on the GEANT4 toolkit (version 8.2). The model takes into account fragmentation of projectile nuclei and…

医学物理 · 物理学 2010-11-03 Igor Pshenichnov , Igor Mishustin , Walter Greiner

We model the responses of Tissue-Equivalent Proportional Counters (TEPC) to radiation fields of therapeutic C-12 beams in a water phantom and to quasi-monoenergetic neutrons in a PMMA phantom. Simulations are performed with the Monte Carlo…

医学物理 · 物理学 2013-07-09 Lucas Burigo , Igor Pshenichnov , Igor Mishustin , Marcus Bleicher

In carbon-therapy, the interaction of the incoming beam with human tissues may lead to the production of a large amount of nuclear fragments and secondary light particles. An accurate estimation of the biological dose deposited into the…

核实验 · 物理学 2014-06-02 J. Dudouet , D. Cussol , D. Durand , M. Labalme

Depth distributions of positron-emitting nuclei in PMMA phantoms are calculated within a Monte Carlo model for Heavy-Ion Therapy (MCHIT) based on the GEANT4 toolkit (version 8.0). The calculated total production rates of $^{11}$C, $^{10}$C…

医学物理 · 物理学 2007-05-23 Igor Pshenichnov , Igor Mishustin , Walter Greiner

We study the spatial distributions of $\beta^+$-activity produced by therapeutic beams of $^3$He and $^{12}$C ions in various tissue-like materials. The calculations were performed within a Monte Carlo model for Heavy-Ion Therapy (MCHIT)…

医学物理 · 物理学 2010-11-03 Igor Pshenichnov , Alexei Larionov , Igor Mishustin , Walter Greiner

We used the GEANT4 Monte Carlo MC Toolkit to simulate carbon ion beams incident on water, tissue, and bone, taking into account nuclear fragmentation reactions. Upon increasing the energy of the primary beam, the position of the Bragg-Peak…

医学物理 · 物理学 2021-02-26 M. Kh. Hamad

It is well known from numerous experiments that nuclear multifragmentation is a dominating mechanism for production of intermediate-mass fragments in nucleus-nucleus collisions at energies above 100 A MeV. In this paper we investigate the…

医学物理 · 物理学 2012-04-18 Igor Pshenichnov , Alexander Botvina , Igor Mishustin , Walter Greiner

Nowadays there is a growing interest in Particle Therapy treatments exploiting light ion beams against tumors due to their enhanced Relative Biological Effectiveness and high space selectivity. In particular promising results are obtained…

A Geant4-based Monte Carlo model for Heavy-Ion Therapy (MCHIT) is used to study radiation fields of H-1, He-4, Li-7 and C-12 beams with similar ranges (~160-180 mm) in water. Microdosimetry spectra are simulated for wall-less and walled…

医学物理 · 物理学 2014-02-10 Lucas Burigo , Igor Pshenichnov , Igor Mishustin , Marcus Bleicher

During therapeutic treatments using ions such as carbon, nuclear interactions between the incident ions and nuclei present in organic tissues may occur, leading to the attenuation of the incident beam intensity and to the production of…

核实验 · 物理学 2014-07-02 J. Dudouet , M. Labalme , D. Cussol , C. Finck , R. Rescigno , M. Rousseau , S. Salvador , M. Vanstalle

For understanding the biological effects of neutrons, predictions of the secondary charged particle distributions by neutron irradiation are needed in biophysical models. We have performed detailed Monte-Carlo simulations using the PHITS…

生物物理 · 物理学 2022-01-17 Sungmin Pak , Francis A. Cucinotta

The goal of this research project is to give quantitative information useful for the design of a g-ray detector to investigate neutron capture (n, g) reactions on radioactive nuclei at the Manuel Lujan Jr. Neutron Scattering Center (MLNSC)…

In the present paper momentum distributions of nuclei produced in the heavy ion beam fragmentation at the relatively low energies (below 100 $A\cdot$MeV) are studied. For this study, a new theoretical approach is developed on the basis of…

核理论 · 物理学 2024-10-23 A. N. Ismailova , Yu. L. Parfenova , P. G. Sharov , D. M. Janseitov

In this study, we employ the Monte Carlo simulations by using the GEANT4 code to demonstrate the capability of muon tomography based on the dual-parameter analysis in the examination of the nuclear waste barrels. Our current hodoscope setup…

仪器与探测器 · 物理学 2022-12-06 Ahmet Ilker Topuz , Madis Kiisk , Andrea Giammanco

Various Li compounds are commonly used at neutron facilities as neutron absorbers. These compounds provide one of the highest ratios of neutron attenuation to $\gamma$-ray production. Unfortunately, the usage of these compounds can also…

仪器与探测器 · 物理学 2016-11-03 Valentina Santoro , Douglas D. Di Julio , Phillip M. Bentley

The neutron emission in projectile fragmentation at relativistic energies was studied with the Large-Area-Neutron-Detector LAND coupled to the ALADIN forward spectrometer at the GSI Schwerionen-Synchrotron (SIS). Stable 124Sn and…

Slowly extracted relativistic beams of light nuclei and a beam transportation line net system constitute a good base for secondary nuclear beams forming at the LHE accelerator facility. A recent years activity in the field at the Laboratory…

核实验 · 物理学 2012-10-05 P. A. Rukoyatkin , L. N. Komolov , R. I. Kukushkina , V. N. Ramzhin , P. I. Zarubin

The Miniaturized Detector for Application in Space (MIDAS) is a compact device with dimensions 5 x 5 x 1 cm3 which combines position sensitive Si detectors and a fast neutrons spectrometer. MIDAS is developed with purpose to act as a linear…

仪器与探测器 · 物理学 2022-02-22 K. Karafasoulis , C. Papadimitropoulos , C. Potiriadis , C. P. Lambropoulos

Experimental and theoretical investigation of the fragmentation reaction in Fermi-energy domain is currently of particular importance for not only the nuclear physics but also some interdisciplinary fields. In the present work, neutron-rich…

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