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We investigate active particles that exhibit long-range interactions only restricted by a field of view, which is characterized by an angle $\beta$. We show that constraining attractive interactions to a field of view leads to the emergence…

生物物理 · 物理学 2026-04-03 Edgardo Brigatti , Fernando Peruani

In this work we mimic the efficient propulsion mechanism of natural cilia by magnetically actuating thin films in a cyclic but non-reciprocating manner. By simultaneously solving the elasto-dynamic, magnetostatic and fluid mechanics…

流体动力学 · 物理学 2009-11-13 S. N. Khaderi , M. G. H. M. Baltussen , P. D. Anderson , D. Ioan , J. M. J. den Toonder , P. R. Onck

Particle-in-cell (PIC) simulations of collisionless jets of electrons and positrons in an ambient electron-proton plasma have revealed an acceleration of positrons at the expense of electron kinetic energy. The dominant instability within…

等离子体物理 · 物理学 2020-11-03 M E Dieckmann , S J Spencer , M Falk , G Rowlands

The force generated between actin and myosin acts predominantly along the direction of the actin filament, resulting in relative sliding of the thick and thin filaments in muscle or transport of myosin cargos along actin tracks. Previous…

生物大分子 · 定量生物学 2015-05-13 John F. Beausang , Harry W. Schroeder , Philip C. Nelson , Yale E. Goldman

Composites of flexible and rigid polymers are ubiquitous in biology and industry alike, yet the physical principles determining their mechanical properties are far from understood. Here, we couple force spectroscopy with large-scale…

Using a simple model, we study the fluctuating dynamics of inextensible, semiflexible polar filaments interacting with active and directed force generating centres such as molecular motors. Taking into account the fact that the activity…

软凝聚态物质 · 物理学 2009-11-07 Tanniemola B. Liverpool

We extend a model for the morphology and dynamics of a crawling eukaryotic cell to describe cells on micropatterned substrates. This model couples cell morphology, adhesion, and cytoskeletal flow in response to active stresses induced by…

细胞行为 · 定量生物学 2015-06-17 Brian A. Camley , Yanxiang Zhao , Bo Li , Herbert Levine , Wouter-Jan Rappel

While semi-flexible polymers and fibers are an important class of material due to their rich mechanical properties, it remains unclear how these properties relate to the microscopic conformation of the polymers. Actin filaments constitute…

Filament based intracellular transport involves the collective action of molecular motor proteins. Experimental evidences suggest that microtubule (MT) filament bound motor proteins such as {\it kinesins} weakly interact among themselves…

软凝聚态物质 · 物理学 2015-06-23 Sameep Chandel , Abhishek Chaudhuri , Sudipto Muhuri

Biological and robotic systems often operate in confined environments where material must be gathered without centralized control. Inspired by the effective collection strategies of aquatic worms (Lumbriculus variegatus and Tubifex…

软凝聚态物质 · 物理学 2025-05-09 R. Sinaasappel , K. R. Prathyusha , H. Tuazon , E. Mirzahossein , P. Illien , S. Bhamla , A. Deblais

Active filaments, such as microtubules with attached cargo-carrying motor proteins, are important dynamic structures for fluid transport in and around living cells. The mathematical models of active filaments appearing in the literature…

流体动力学 · 物理学 2025-08-19 Ilteber R. Ozdemir , Bethany Clarke , Yongyun Hwang , Eric E. Keaveny

Polymerization of dendritic actin networks underlies important mechanical processes in cell biology such as the protrusion of lamellipodia, propulsion of growth cones in dendrites of neurons, intracellular transport of organelles and…

生物物理 · 物理学 2021-03-17 Rohan Abeyaratne , Prashant K. Purohit

The mechanism of multivalent counterion-induced bundle formation by filamentous actin (F-actin) is studied using a coarse-grained model and molecular dynamics simulation. Real diameter size, helically ordered charge distribution and twist…

软凝聚态物质 · 物理学 2012-03-01 Sarah Mohammadinejad , Ramin Golestanian , Hossein Fazli

Cellular biology abound with filaments interacting through fluids, from intracellular microtubules, to rotating flagella and beating cilia. While previous work has demonstrated the complexity of capturing nonlocal hydrodynamic interactions…

流体动力学 · 物理学 2016-12-21 Yi Man , Lyndon Koens , Eric Lauga

We analyse a generic motility model, with the motility mechanism arising by contractile stress due to the interaction of myosin and actin. A hydrodynamic active polar gel theory is used to model the cytoplasm of a cell and is combined with…

细胞行为 · 定量生物学 2015-07-06 Wieland Marth , Simon Praetorius , Axel Voigt

The behavior of mobile linkers connecting two semi-flexible charged polymers, such as polyvalent counterions connecting DNA or F-actin chains, is studied theoretically. The chain bending rigidity induces an effective repulsion between…

软凝聚态物质 · 物理学 2009-11-07 I. Borukhov , R. F. Bruinsma , W. M. Gelbart , A. J. Liu

Myxococcus xanthus is a model organism for studying bacterial social behaviors due to its ability to form complex multi-cellular structures. Knowledge of M. xanthus surface gliding motility and the mechanisms that coordinate it are…

Amoeboid cell migration is characterized by frequent changes of the direction of motion and resembles a persistent random walk on long time scales. Although it is well known that cell migration is typically driven by the actin cytoskeleton,…

生物物理 · 物理学 2021-06-09 Nicolas Ecker , Karsten Kruse

Biological locomotion in nature is often achieved by the interaction between a flexible body and its surrounding medium. The interaction of a flexible body with granular media is less understood compared with viscous fluids partially due to…

流体动力学 · 物理学 2017-08-03 Zhiwei Peng , Yang Ding , Kyle Pietrzyk , Gwynn J. Elfring , On Shun Pak

The locomotion of flexible membrane-like organisms on top of curved surfaces appears in different contexts and scales. Still, such dynamics have not yet been quantitatively modeled and no realization of such motion in manmade systems has…

软凝聚态物质 · 物理学 2024-02-27 Omri Y. Cohen , Yael Klein , Eran Sharon