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We propose a multivariate GARCH model for non-stationary health time series by modifying the variance of the observations of the standard state space model. The proposed model provides an intuitive way of dealing with heteroskedastic data…

统计方法学 · 统计学 2023-03-16 Zayd Omar , David A. Stephens , Alexandra M. Schmidt , David L. Buckeridge

Mathematical models of cognition are often memoryless and ignore potential fluctuations of their parameters. However, human cognition is inherently dynamic. Thus, we propose to augment mechanistic cognitive models with a temporal dimension…

统计方法学 · 统计学 2023-09-21 Lukas Schumacher , Paul-Christian Bürkner , Andreas Voss , Ullrich Köthe , Stefan T. Radev

Surrogate testing techniques have been used widely to investigate the presence of dynamical nonlinearities, an essential ingredient of deterministic chaotic processes. Traditional surrogate testing subscribes to statistical hypothesis…

信号处理 · 电气工程与系统科学 2019-07-18 Radhakrishnan Nagarajan

We propose a Bayesian nonparametric approach for the noise reduction of a given chaotic time series contaminated by dynamical noise, based on Markov Chain Monte Carlo methods (MCMC). The underlying unknown noise process (possibly) exhibits…

统计方法学 · 统计学 2018-07-04 Konstantinos Kaloudis , Spyridon J. Hatjispyros

The asymmetry of coupling between complex systems can be studied by conditional probabilities of recurrence, which can be estimated by joint recurrence plots. This approach is applied for the first time on experimental data: time series of…

混沌动力学 · 物理学 2013-06-05 Norbert Marwan , Yong Zou , Niels Wessel , Maik Riedl , Jürgen Kurths

Nonlinear systems are capable of displaying complex behavior even if this is the result of a small number of interacting time scales. A widely studied case is when complex dynamics emerges out of a nonlinear system being forced by a simple…

定量方法 · 定量生物学 2015-06-01 Leandro M. Alonso

This study performs parameter inference in a partial differential equations system of pulmonary circulation. We use a fluid dynamics network model that takes selected parameter values and mimics the behaviour of the pulmonary haemodynamics…

Many studies of biomedical time series signals aim to measure the association between frequency-domain properties of time series and clinical and behavioral covariates. However, the time-varying dynamics of these associations are largely…

统计方法学 · 统计学 2016-10-05 Scott A. Bruce , Martica H. Hall , Daniel J. Buysse , Robert T. Krafty

Recent studies have shown that Postural Orthostatic Tachycardia Syndrome (POTS) patients have abnormal low frequency $\approx 0.1$ Hz blood pressure and heart rate dynamics. These dynamics are attributed to the baroreflex and can give…

组织与器官 · 定量生物学 2021-09-30 Justen Geddes , Johnny T Ottesen , Jesper Mehlsen , Mette S. Olufsen

Control barrier functions are widely used to synthesize safety-critical controls. However, the presence of Gaussian-type noise in dynamical systems can generate unbounded signals and potentially result in severe consequences. Although…

系统与控制 · 电气工程与系统科学 2023-12-21 Chuanzheng Wang , Yiming Meng , Jun Liu , Stephen Smith

Network inference has been extensively studied in several fields, such as systems biology and social sciences. Learning network topology and internal dynamics is essential to understand mechanisms of complex systems. In particular, sparse…

机器学习 · 统计学 2022-06-13 Yasen Wang , Junyang Jin , Jorge Goncalves

Dynamic invariants are often estimated from experimental time series with the aim of differentiating between different physical states in the underlying system. The most popular schemes for estimating dynamic invariants are capable of…

混沌动力学 · 物理学 2007-05-23 Michael Small

Performing inference over simulators is generally intractable as their runtime means we cannot compute a marginal likelihood. We develop a likelihood-free inference method to infer parameters for a cardiac simulator, which replicates…

机器学习 · 统计学 2017-12-12 Adam McCarthy , Blanca Rodriguez , Ana Minchole

Differential equations based on physical principals are used to represent complex dynamic systems in all fields of science and engineering. Through repeated use in both academics and industry, these equations have been shown to represent…

统计方法学 · 统计学 2022-09-08 Joshua S. North , Christopher K. Wikle , Erin M. Schliep

Echocardiography plays a fundamental role in the extraction of important clinical parameters (e.g. left ventricular volume and ejection fraction) required to determine the presence and severity of heart-related conditions. When deploying…

计算机视觉与模式识别 · 计算机科学 2025-02-19 Thierry Judge , Olivier Bernard , Woo-Jin Cho Kim , Alberto Gomez , Arian Beqiri , Agisilaos Chartsias , Pierre-Marc Jodoin

Objective: to develop quantitative methods for the clinical interpretation of the ballistocardiogram (BCG). Methods: a closed-loop mathematical model of the cardiovascular system is proposed to theoretically simulate the mechanisms…

Understanding how stochastic gene expression is regulated in biological systems using snapshots of single-cell transcripts requires state-of-the-art methods of computational analysis and statistical inference. A Bayesian approach to…

定量方法 · 定量生物学 2018-12-10 Yen Ting Lin , Nicolas E. Buchler

In the realm of big data, discerning patterns in nonlinear systems affected by external control inputs is increasingly challenging. Our approach blends the coarse-graining strengths of centroid-based unsupervised clustering with the clarity…

流体动力学 · 物理学 2023-12-25 Nitish Arya , Aditya G. Nair

Interacting systems are prevalent in nature. It is challenging to accurately predict the dynamics of the system if its constituent components are analyzed independently. We develop a graph-based model that unveils the systemic interactions…

机器学习 · 计算机科学 2024-10-31 Giangiacomo Mercatali , Andre Freitas , Jie Chen

In this work, we propose a novel deep bootstrap framework for nonparametric regression based on conditional diffusion models. Specifically, we construct a conditional diffusion model to learn the distribution of the response variable given…

机器学习 · 统计学 2026-02-12 Jinyuan Chang , Yuling Jiao , Lican Kang , Junjie Shi