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Eukaryotic DNA replication follows a specific temporal program, with some genomic regions consistently replicating earlier than others, yet what determines this program is largely unknown. Highly transcribed regions have been observed to…

基因组学 · 定量生物学 2013-08-12 Hunter B. Fraser

The inverse relationship between the length of a word and the frequency of its use, first identified by G.K. Zipf in 1935, is a classic empirical law that holds across a wide range of human languages. We demonstrate that length is one…

计算与语言 · 计算机科学 2017-06-02 Stephan C. Meylan , Thomas L. Griffiths

It is staggering that words of the English language, which are on average represented by 5--6 bytes of ASCII, require as much as 24 kilobytes when served to large language models. We show that there is room for more information in every…

机器学习 · 计算机科学 2024-11-01 Peter Belcak , Roger Wattenhofer

Word frequency is assumed to correlate with word familiarity, but the strength of this correlation has not been thoroughly investigated. In this paper, we report on our analysis of the correlation between a word familiarity rating list…

计算与语言 · 计算机科学 2018-06-12 Kumiko Tanaka-Ishii , Hiroshi Terada

We show that confidence intervals in a variance component model, with asymptotically correct uniform coverage probability, can be obtained by inverting certain test-statistics based on the score for the restricted likelihood. The results…

统计方法学 · 统计学 2024-11-05 Yiqiao Zhang , Karl Oskar Ekvall , Aaron J. Molstad

Designing short DNA words is a problem of constructing a set (i.e., code) of n DNA strings (i.e., words) with the minimum length such that the Hamming distance between each pair of words is at least k and the n words satisfy a set of…

数据结构与算法 · 计算机科学 2012-02-01 Ming-Yang Kao , Henry C. M. Leung , He Sun , Yong Zhang

The genome-wide recombination rate ($RR$) of a species is often described by one parameter, the ratio between total genetic map length ($G$) and physical map length ($P$), measured in centiMorgans per Megabase (cM/Mb). The value of this…

基因组学 · 定量生物学 2011-03-16 Wentian Li , Jan Freudenberg

Standard decoding strategies for text generation, including top-k, nucleus sampling, and contrastive search, select tokens based on likelihood, restricting selection to high-probability regions. Human language production operates…

计算与语言 · 计算机科学 2026-03-20 Esteban Garces Arias , Nurzhan Sapargali , Christian Heumann , Matthias Aßenmacher

We investigate how neural language models acquire individual words during training, extracting learning curves and ages of acquisition for over 600 words on the MacArthur-Bates Communicative Development Inventory (Fenson et al., 2007).…

计算与语言 · 计算机科学 2021-10-07 Tyler A. Chang , Benjamin K. Bergen

Using human evaluation of 100,000 words spread across 24 corpora in 10 languages diverse in origin and culture, we present evidence of a deep imprint of human sociality in language, observing that (1) the words of natural human language…

We refine a uniform algebraic approach for deriving upper bounds on reset thresholds of synchronizing automata. We express the condition that an automaton is synchronizing in terms of linear algebra, and obtain upper bounds for the reset…

形式语言与自动机理论 · 计算机科学 2015-12-21 Mikhail Berlinkov , Marek Szykuła

The emergence of discourse-like tokens such as "wait" and "therefore" in large language models (LLMs) has offered a unique window into their reasoning processes. However, systematic analyses of how such signals vary across training…

计算与语言 · 计算机科学 2026-01-27 Jaehui Hwang , Dongyoon Han , Sangdoo Yun , Byeongho Heo

We analyze the occurrence frequencies of over 15 million words recorded in millions of books published during the past two centuries in seven different languages. For all languages and chronological subsets of the data we confirm that two…

物理与社会 · 物理学 2012-12-12 Alexander M. Petersen , Joel N. Tenenbaum , Shlomo Havlin , H. Eugene Stanley , Matjaz Perc

Fix two words over the binary alphabet $\{0,1\}$, and generate iid Bernoulli$(p)$ bits until one of the words occurs in sequence. This setup, commonly known as Penney's ante, was popularized by Conway, who found (in unpublished work) a…

组合数学 · 数学 2024-10-01 Mathew Drexel , Xuanshan Peng , Jacob Richey

Recursive processing in sentence comprehension is considered a hallmark of human linguistic abilities. However, its underlying neural mechanisms remain largely unknown. We studied whether a modern artificial neural network trained with…

计算与语言 · 计算机科学 2021-05-04 Yair Lakretz , Dieuwke Hupkes , Alessandra Vergallito , Marco Marelli , Marco Baroni , Stanislas Dehaene

We study here the so called subsequence pattern matching also known as hidden pattern matching in which one searches for a given pattern $w$ of length $m$ as a subsequence in a random text of length $n$. The quantity of interest is the…

概率论 · 数学 2020-03-24 Svante Janson , Wojciech Szpankowski

We study the complexity of the problem of searching for a set of patterns that separate two given sets of strings. This problem has applications in a wide variety of areas, most notably in data mining, computational biology, and in…

计算复杂性 · 计算机科学 2016-12-20 Giuseppe Lancia , Luke Mathieson , Pablo Moscato

To maintain coherence in language, the brain must satisfy key competing temporal demands: the gradual accumulation of meaning across extended context (drift) and the rapid reconfiguration of representations at event boundaries (shift). How…

Language models, especially transformer-based ones, have achieved colossal success in NLP. To be precise, studies like BERT for NLU and works like GPT-3 for NLG are very important. If we consider DNA sequences as a text written with an…

基因组学 · 定量生物学 2026-01-21 Musa Nuri Ihtiyar , Arzucan Ozgur

Motivated by DNA data storage, we study the expected number of coded symbols drawn from a linear code until a desired information symbol can be decoded - the random access expectation. We focus on generator matrices with a type of symmetry,…

信息论 · 计算机科学 2026-05-19 Christoph Hofmeister , Rawad Bitar , Eitan Yaakobi