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Privacy-preserving genomic data sharing is prominent to increase the pace of genomic research, and hence to pave the way towards personalized genomic medicine. In this paper, we introduce ($\epsilon , T$)-dependent local differential…

密码学与安全 · 计算机科学 2021-02-16 Emre Yilmaz , Tianxi Ji , Erman Ayday , Pan Li

We introduce the coverage correlation coefficient, a novel nonparametric measure of statistical association designed to quantifies the extent to which two random variables have a joint distribution concentrated on a singular subset with…

统计方法学 · 统计学 2025-08-18 Xuzhi Yang , Mona Azadkia , Tengyao Wang

This paper examines two methods for finding whether long-range correlations exist in DNA: a fractal measure and a mutual information technique. We evaluate the performance and implications of these methods in detail. In particular we…

种群与进化 · 定量生物学 2007-05-23 Matthew J. Berryman , Andrew Allison , Derek Abbott

When faced with a new dataset, most practitioners begin by performing exploratory data analysis to discover interesting patterns and characteristics within data. Techniques such as association rule mining are commonly applied to uncover…

机器学习 · 计算机科学 2021-02-03 Andrew Lensen

Symbolic regression (SR) aims to find symbolic expressions that describe datasets. Due to its inherent interpretability, is a powerful paradigm for scientific discovery. Recent advances have expanded SR to describe related phenomena using a…

机器学习 · 计算机科学 2026-03-31 Viktor Martinek , Roland Herzog

Score matching is an estimation procedure that has been developed for statistical models whose probability density function is known up to proportionality but whose normalizing constant is intractable, so that maximum likelihood is…

统计方法学 · 统计学 2024-04-23 Jiazhen Xu , Janice L. Scealy , Andrew T. A. Wood , Tao Zou

Canonical correlation analysis is a technique to extract common features from a pair of multivariate data. In complex situations, however, it does not extract useful features because of its linearity. On the other hand, kernel method used…

机器学习 · 计算机科学 2007-05-23 Shotaro Akaho

We investigate the problem of jointly testing two hypotheses and estimating a random parameter based on data that is observed sequentially by sensors in a distributed network. In particular, we assume the data to be drawn from a Gaussian…

信号处理 · 电气工程与系统科学 2020-03-04 Dominik Reinhard , Michael Fauß , Abdelhak M. Zoubir

Statistical divergence is widely applied in multimedia processing, basically due to regularity and interpretable features displayed in data. However, in a broader range of data realm, these advantages may no longer be feasible, and…

数据库 · 计算机科学 2020-11-20 Ruoyu Wang , Xiaobo Hu , Daniel Sun , Guoqiang Li , Raymond Wong , Shiping Chen , Jianquan Liu

Transcriptomic analysis are characterized by being not directly quantitative and only providing relative measurements of expression levels up to an unknown individual scaling factor. This difficulty is enhanced for differential expression…

统计方法学 · 统计学 2021-03-24 Dorota Desaulle , Céline Hoffmann , Bernard Hainque , Yves Rozenholc

Detecting dependence between variables is a crucial issue in statistical science. In this paper, we propose a novel metric called label projection correlation to measure the dependence between numerical and categorical variables. The…

统计方法学 · 统计学 2025-06-24 Yixiao Liu , Pengjian Shang

We propose generalized additive partial linear models for complex data which allow one to capture nonlinear patterns of some covariates, in the presence of linear components. The proposed method improves estimation efficiency and increases…

统计理论 · 数学 2014-05-26 Li Wang , Lan Xue , Annie Qu , Hua Liang

In this paper, the problem of matching pairs of correlated random graphs with multi-valued edge attributes is considered. Graph matching problems of this nature arise in several settings of practical interest including social network…

信息论 · 计算机科学 2018-02-06 F. Shirani , S. Garg , E. Erkip

Traditional statistical methods for confidentiality protection of statistical databases do not scale well to deal with GWAS (genome-wide association studies) databases especially in terms of guarantees regarding protection from linkage to…

统计方法学 · 统计学 2012-05-04 Caroline Uhler , Aleksandra B. Slavkovic , Stephen E. Fienberg

Feature screening is useful and popular to detect informative predictors for ultrahigh-dimensional data before developing proceeding statistical analysis or constructing statistical models. While a large body of feature screening procedures…

统计方法学 · 统计学 2020-08-12 Li-Pang Chen

The detection of similarities between long DNA and protein sequences is studied using concepts of statistical physics. It is shown that mutual similarities can be detected by sequence alignment methods only if their amount exceeds a…

凝聚态物理 · 物理学 2009-10-28 Terence Hwa , Michael Lassig

Using evolutionary computation algorithms to solve multiple tasks with knowledge sharing is a promising approach. Image feature learning can be considered as a multitask problem because different tasks may have a similar feature space.…

计算机视觉与模式识别 · 计算机科学 2021-07-16 Ying Bi , Bing Xue , Mengjie Zhang

Motivation: Array Comparative Genomic Hybridization (aCGH) is used to scan the entire genome for variations in DNA copy number. A central task in the analysis of aCGH data is the segmentation into groups of probes sharing the same DNA copy…

定量方法 · 定量生物学 2008-04-29 Erez Ben-Yaacov , Yonina Eldar

Detecting differences in gene expression is an important part of single-cell RNA sequencing experiments, and many statistical methods have been developed for this aim. Most differential expression analyses focus on comparing expression…

In this paper we propose a Bayesian answer to testing problems when the hypotheses are not well separated. The idea of the method is to study the posterior distribution of a discrepancy measure between the parameter and the model we want to…

统计理论 · 数学 2017-06-28 Jean-Bernard Salomond