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Multiple hypothesis testing with false discovery rate (FDR) control is a fundamental problem in statistical inference, with broad applications in genomics, drug screening, and outlier detection. In many such settings, researchers may have…

统计方法学 · 统计学 2026-02-19 Yonghoon Lee , Meshi Bashari , Edgar Dobriban , Yaniv Romano

The complexity of deep neural networks (DNNs) makes them powerful but also makes them challenging to interpret, hindering their applicability in error-intolerant domains. Existing methods attempt to reason about the internal mechanism of…

机器学习 · 计算机科学 2023-09-28 Winston Chen , William Stafford Noble , Yang Young Lu

Variable selection has been widely used in data analysis for the past decades, and it becomes increasingly important in the Big Data era as there are usually hundreds of variables available in a dataset. To enhance interpretability of a…

统计方法学 · 统计学 2020-08-17 Yuxiang Xie , Kwun Chuen Gary Chan

E-values have gained attention as potential alternatives to p-values as measures of uncertainty, significance and evidence. In brief, e-values are realized by random variables with expectation at most one under the null; examples include…

统计理论 · 数学 2021-12-16 Ruodu Wang , Aaditya Ramdas

Penalized regression methods are an attractive tool for high-dimensional data analysis, but their widespread adoption has been hampered by the difficulty of applying inferential tools. In particular, the question "How reliable is the…

统计理论 · 数学 2026-05-13 Patrick Breheny

This paper proposes novel inferential procedures for discovering the network Granger causality in high-dimensional vector autoregressive models. In particular, we mainly offer two multiple testing procedures designed to control the false…

统计方法学 · 统计学 2024-11-14 Yoshimasa Uematsu , Takashi Yamagata

This paper investigates sequential change-point detection in reconfigurable sensor networks. In this problem, data from multiple sensors are observed sequentially. Each sensor can have a unique change point, and the data distribution…

统计方法学 · 统计学 2025-04-10 Seungwon Lee , Yunxiao Chen , Xiaoou Li

This paper explores the multiple testing problem for sparse high-dimensional data with binary outcomes. We propose novel empirical Bayes multiple testing procedures based on a spike-and-slab posterior and then evaluate their performance in…

统计理论 · 数学 2025-06-16 Yu-Chien Bo Ning

False discovery rate (FDR) control is a popular approach for maintaining the integrity of statistical analyses, especially in high-dimensional data settings, where multiple comparisons increase the risk of false positives. FDR control has…

信号处理 · 电气工程与系统科学 2026-03-03 Fabian Scheidt , Jasin Machkour , Michael Muma

In this paper, the problem of error control of stepwise multiple testing procedures is considered. For two-sided hypotheses, control of both type 1 and type 3 (or directional) errors is required, and thus mixed directional familywise error…

统计理论 · 数学 2016-02-10 Wenge Guo , Joseph P. Romano

A scientist tests a continuous stream of hypotheses over time in the course of her investigation -- she does not test a predetermined, fixed number of hypotheses. The scientist wishes to make as many discoveries as possible while ensuring…

统计方法学 · 统计学 2023-11-14 Ziyu Xu , Aaditya Ramdas

Differentially private multiple testing procedures can protect the information of individuals used in hypothesis tests while guaranteeing a small fraction of false discoveries. In this paper, we propose a differentially private adaptive FDR…

机器学习 · 统计学 2023-06-01 Xintao Xia , Zhanrui Cai

Large-scale multiple two-sample {\em Student}'s $t$ testing problems often arise from the statistical analysis of scientific data. To detect components with different values between two mean vectors, a well-known procedure is to apply the…

统计方法学 · 统计学 2014-10-17 Weidong Liu

Fast multiple change-point segmentation methods, which additionally provide faithful statistical statements on the number, locations and sizes of the segments, have recently received great attention. In this paper, we propose a multiscale…

统计理论 · 数学 2016-04-15 Housen Li , Axel Munk , Hannes Sieling

Large-scale multiple testing with correlated and heavy-tailed data arises in a wide range of research areas from genomics, medical imaging to finance. Conventional methods for estimating the false discovery proportion (FDP) often ignore the…

统计方法学 · 统计学 2018-09-19 Jianqing Fan , Yuan Ke , Qiang Sun , Wen-Xin Zhou

Simultaneously performing variable selection and inference in high-dimensional models is an open challenge in statistics and machine learning. The increasing availability of vast amounts of variables requires the adoption of specific…

统计方法学 · 统计学 2025-10-02 Marco Molinari , Magne Thoresen

This article considers the problem of multiple hypothesis testing using $t$-tests. The observed data are assumed to be independently generated conditional on an underlying and unknown two-state hidden model. We propose an asymptotically…

统计理论 · 数学 2011-02-22 Hongyuan Cao , Michael R. Kosorok

We provide new non-asymptotic false discovery proportion (FDP) confidence envelopes in several multiple testing settings relevant for modern high dimensional-data methods. We revisit the multiple testing scenarios considered in the recent…

统计理论 · 数学 2024-09-18 Iqraa Meah , Gilles Blanchard , Etienne Roquain

Most link prediction methods return estimates of the connection probability of missing edges in a graph. Such output can be used to rank the missing edges from most to least likely to be a true edge, but does not directly provide a…

统计方法学 · 统计学 2024-03-26 Ariane Marandon

Empirical research in the social and medical sciences frequently involves testing multiple hypotheses simultaneously, increasing the risk of false positives due to chance. Classical multiple testing procedures, such as the Bonferroni…

计量经济学 · 经济学 2025-07-29 Sebastian Calonico , Sebastian Galiani
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