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Background: Mendelian randomization (MR) is a useful approach to causal inference from observational studies when randomised controlled trials are not feasible. However, study heterogeneity of two association studies required in MR is often…

统计方法学 · 统计学 2021-12-16 Linyi Zou , Hui Guo , Carlo Berzuini

Parameter inference is a fundamental problem in data-driven modeling. Given observed data that is believed to be a realization of some parameterized model, the aim is to find parameter values that are able to explain the observed data. In…

数据结构与算法 · 计算机科学 2016-04-20 Carlo Albert , Simone Ulzega , Ruedi Stoop

Bayesian hierarchical modeling is a popular approach to capturing unobserved heterogeneity across individual units. However, standard estimation methods such as Markov chain Monte Carlo (MCMC) can be impracticable for modeling outcomes from…

统计方法学 · 统计学 2014-11-04 Michael Braun , Paul Damien

Nonparametric regression for massive numbers of samples (n) and features (p) is an increasingly important problem. In big n settings, a common strategy is to partition the feature space, and then separately apply simple models to each…

机器学习 · 统计学 2014-06-10 Rajarshi Guhaniyogi , David B. Dunson

A nonparametric Bayes approach is proposed for the problem of estimating a sparse sequence based on Gaussian random variables. We adopt the popular two-group prior with one component being a point mass at zero, and the other component being…

统计方法学 · 统计学 2017-05-31 Yunbo Ouyang , Feng Liang

Variable selection and classification are common objectives in the analysis of high-dimensional data. Most such methods make distributional assumptions that may not be compatible with the diverse families of distributions data can take. A…

统计方法学 · 统计学 2019-08-28 Weichang Yu , Lamiae Azizi , John T. Ormerod

Bayesian low-rank matrix factorization techniques have become an essential tool for relational data analysis and matrix completion. A standard approach is to assign zero-mean Gaussian priors on the columns or rows of factor matrices to…

机器学习 · 统计学 2020-11-11 Saibal De , Hadi Salehi , Alex Gorodetsky

Practitioners of Bayesian statistics have long depended on Markov chain Monte Carlo (MCMC) to obtain samples from intractable posterior distributions. Unfortunately, MCMC algorithms are typically serial, and do not scale to the large…

机器学习 · 统计学 2015-06-11 Maxim Rabinovich , Elaine Angelino , Michael I. Jordan

Bayesian inference allows us to define a posterior distribution over the weights of a generic neural network (NN). Exact posteriors are usually intractable, in which case approximations can be employed. One such approximation - variational…

机器学习 · 计算机科学 2026-01-30 Andrew Millard , Joshua Murphy , Peter Green , Simon Maskell

In image reconstruction, an accurate quantification of uncertainty is of great importance for informed decision making. Here, the Bayesian approach to inverse problems can be used: the image is represented through a random function that…

数值分析 · 数学 2025-04-24 Jonas Latz , Aretha L. Teckentrup , Simon Urbainczyk

We present a novel Bayesian inference tool that uses a neural network to parameterise efficient Markov Chain Monte-Carlo (MCMC) proposals. The target distribution is first transformed into a diagonal, unit variance Gaussian by a series of…

宇宙学与河外天体物理 · 物理学 2020-06-03 Adam Moss

This paper introduces a Bayesian framework that combines Markov chain Monte Carlo (MCMC) sampling, dimensionality reduction, and neural density estimation to efficiently handle inverse problems that (i) must be solved multiple times, and…

计算工程、金融与科学 · 计算机科学 2026-02-24 Giacomo Bottacini , Matteo Torzoni , Andrea Manzoni

Markov Chain Monte Carlo (MCMC) is a well-established family of algorithms primarily used in Bayesian statistics to sample from a target distribution when direct sampling is challenging. Existing work on Bayesian decision trees uses MCMC.…

统计计算 · 统计学 2023-01-24 Efthyvoulos Drousiotis , Paul G. Spirakis , Simon Maskell

We consider the problem of optimizing a real-valued continuous function $f$ using a Bayesian approach, where the evaluations of $f$ are chosen sequentially by combining prior information about $f$, which is described by a random process…

最优化与控制 · 数学 2011-11-22 Romain Benassi , Julien Bect , Emmanuel Vazquez

Bayesian learning is built on an assumption that the model space contains a true reflection of the data generating mechanism. This assumption is problematic, particularly in complex data environments. Here we present a Bayesian…

机器学习 · 统计学 2018-11-05 S. P. Lyddon , S. G. Walker , C. C. Holmes

Gaussian processes are a natural way of defining prior distributions over functions of one or more input variables. In a simple nonparametric regression problem, where such a function gives the mean of a Gaussian distribution for an…

数据分析、统计与概率 · 物理学 2008-02-03 Radford M. Neal

A fully Bayesian approach is proposed for ultrahigh-dimensional nonparametric additive models in which the number of additive components may be larger than the sample size, though ideally the true model is believed to include only a small…

统计方法学 · 统计学 2013-09-24 Zuofeng Shang , Ping Li

Discrete data are abundant and often arise as counts or rounded data. These data commonly exhibit complex distributional features such as zero-inflation, over-/under-dispersion, boundedness, and heaping, which render many parametric models…

统计方法学 · 统计学 2023-02-27 Daniel R. Kowal , Bohan Wu

In many application areas, data are collected on a categorical response and high-dimensional categorical predictors, with the goals being to build a parsimonious model for classification while doing inferences on the important predictors.…

统计方法学 · 统计学 2013-01-22 Yun Yang , David B. Dunson

Due to the escalating growth of big data sets in recent years, new Bayesian Markov chain Monte Carlo (MCMC) parallel computing methods have been developed. These methods partition large data sets by observations into subsets. However, for…

统计方法学 · 统计学 2019-01-21 Zheng Wei , Erin M. Conlon