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The recent advances in sequencing technologies enables the assembly of individual genomes to the reference quality. How to integrate multiple genomes from the same species and to make the integrated representation accessible to biologists…

基因组学 · 定量生物学 2020-03-16 Heng Li , Xiaowen Feng , Chong Chu

Graph Convolutional Networks (GCNs) are powerful for processing graph-structured data and have achieved state-of-the-art performance in several tasks such as node classification, link prediction, and graph classification. However, it is…

机器学习 · 计算机科学 2021-10-19 Langzhang Liang , Cuiyun Gao , Shiyi Chen , Shishi Duan , Yu pan , Junjin Zheng , Lei Wang , Zenglin Xu

Kernel Regularized Least Squares (KRLS) is a popular method for flexibly estimating models that may have complex relationships between variables. However, its usefulness to many researchers is limited for two reasons. First, existing…

机器学习 · 统计学 2023-09-12 Qing Chang , Max Goplerud

Graph pattern matching is a routine process for a wide variety of applications such as social network analysis. It is typically defined in terms of subgraph isomorphism which is NP-Complete. To lower its complexity, many extensions of graph…

数据库 · 计算机科学 2018-04-13 Houari Mahfoud

We propose a novel method to cluster gene networks. Based on a dissimilarity built using correlation structures, we consider networks that connect all the genes based on the strength of their dissimilarity. The large number of genes require…

统计理论 · 数学 2016-07-07 A-C Brunet , J-M Azais , J-M Loubes , J Amar , R Burcelin

Mapper, a topological algorithm, is frequently used as an exploratory tool to build a graphical representation of data. This representation can help to gain a better understanding of the intrinsic shape of high-dimensional genomic data and…

基因组学 · 定量生物学 2023-07-19 Erik J. Amézquita , Farzana Nasrin , Kathleen M. Storey , Masato Yoshizawa

Spectral clustering is a powerful technique for clustering high-dimensional data, utilizing graph-based representations to detect complex, non-linear structures and non-convex clusters. The construction of a similarity graph is essential…

机器学习 · 计算机科学 2025-01-27 Kamal Berahmand , Farid Saberi-Movahed , Razieh Sheikhpour , Yuefeng Li , Mahdi Jalili

We propose a neural multi-document summarization (MDS) system that incorporates sentence relation graphs. We employ a Graph Convolutional Network (GCN) on the relation graphs, with sentence embeddings obtained from Recurrent Neural Networks…

计算与语言 · 计算机科学 2017-08-24 Michihiro Yasunaga , Rui Zhang , Kshitijh Meelu , Ayush Pareek , Krishnan Srinivasan , Dragomir Radev

Genome-wide association studies (GWA studies or GWAS) investigate the relationships between genetic variants such as single-nucleotide polymorphisms (SNPs) and individual traits. Recently, incorporating biological priors together with…

机器学习 · 统计学 2017-09-13 Tao Yang , Paul Thompson , Sihai Zhao , Jieping Ye

Spectral Clustering is one of the most traditional methods to solve segmentation problems. Based on Normalized Cuts, it aims at partitioning an image using an objective function defined by a graph. Despite their mathematical attractiveness,…

计算机视觉与模式识别 · 计算机科学 2024-06-10 Rahul Palnitkar , Jeova Farias Sales Rocha Neto

Genetic programming is a powerful heuristic search technique that is used for a number of real world applications to solve among others regression, classification, and time-series forecasting problems. A lot of progress towards a theoretic…

神经与进化计算 · 计算机科学 2013-09-24 Gabriel Kronberger , Stephan Winkler , Michael Affenzeller , Andreas Beham , Stefan Wagner

Graph Neural Networks (GNNs) leverage the graph structure to transmit information between nodes, typically through the message-passing mechanism. While these models have found a wide variety of applications, they are known to suffer from…

机器学习 · 计算机科学 2025-10-23 Hugh Blayney , Álvaro Arroyo , Xiaowen Dong , Michael M. Bronstein

The search for symbolic regression models with genetic programming (GP) has a tendency of revisiting expressions in their original or equivalent forms. Repeatedly evaluating equivalent expressions is inefficient, as it does not immediately…

机器学习 · 计算机科学 2025-04-09 Fabricio Olivetti de Franca , Gabriel Kronberger

Infrared and visible image fusion aims to extract complementary features to synthesize a single fused image. Many methods employ convolutional neural networks (CNNs) to extract local features due to its translation invariance and locality.…

计算机视觉与模式识别 · 计算机科学 2023-11-02 Jing Li , Lu Bai , Bin Yang , Chang Li , Lingfei Ma , Edwin R. Hancock

Sampling is a widely used graph reduction technique to accelerate graph computations and simplify graph visualizations. By comprehensively analyzing the literature on graph sampling, we assume that existing algorithms cannot effectively…

社会与信息网络 · 计算机科学 2020-09-17 Ying Zhao , Haojin Jiang , Qi'an Chen , Yaqi Qin , Huixuan Xie , Yitao Wu Shixia Liu , Zhiguang Zhou , Jiazhi Xia , Fangfang Zhou

Gene duplication is a fundamental evolutionary mechanism that contributes to biological complexity and diversity (Fortna et al., 2004). Traditionally, research has focused on the duplication of gene sequences (Zhang, 1914). However,…

分子网络 · 定量生物学 2024-05-07 Ashley Scruse , Jonathan Arnold , Robert Robinson

The effort to understand network systems in increasing detail has resulted in a diversity of methods designed to extract their large-scale structure from data. Unfortunately, many of these methods yield diverging descriptions of the same…

数据分析、统计与概率 · 物理学 2015-03-27 Tiago P. Peixoto

Microarrays have become extremely useful for analysing genetic phenomena, but establishing a relation between microarray analysis results (typically a list of genes) and their biological significance is often difficult. Currently, the…

定量方法 · 定量生物学 2007-05-23 Franck Rapaport , Andrei Zinovyev , Marie Dutreix , Emmanuel Barillot , Jean-Philippe Vert

Vectorial Genetic Programming (Vec-GP) extends GP by allowing vectors as input features along regular, scalar features, using them by applying arithmetic operations component-wise or aggregating vectors into scalars by some aggregation…

神经与进化计算 · 计算机科学 2023-03-07 Philipp Fleck , Stephan Winkler , Michael Kommenda , Michael Affenzeller

Over the last decade, a large variety of clustering algorithms have been developed to detect coregulatory relationships among genes from microarray gene expression data. Model based clustering approaches have emerged as statistically well…

定量方法 · 定量生物学 2008-01-15 Anagha Joshi , Yves Van de Peer , Tom Michoel