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At the core of high throughput DNA sequencing platforms lies a bio-physical surface process that results in a random geometry of clusters of homogenous short DNA fragments typically hundreds of base pairs long - bridge amplification. The…

基因组学 · 定量生物学 2015-08-13 Eliza O'Reilly , Francois Baccelli , Gustavo de Veciana , Haris Vikalo

Lifelong SLAM considers long-term operation of a robot where already mapped locations are revisited many times in changing environments. As a result, traditional graph-based SLAM approaches eventually become extremely slow due to the…

机器人学 · 计算机科学 2021-10-05 Gerhard Kurz , Matthias Holoch , Peter Biber

Frequent pattern mining is widely used to find ``important'' or ``interesting'' patterns in data. While it is not easy to mathematically define such patterns, maximal frequent patterns are promising candidates, as frequency is a natural…

数据结构与算法 · 计算机科学 2025-04-08 Giovanni Buzzega , Alessio Conte , Yasuaki Kobayashi , Kazuhiro Kurita , Giulia Punzi

We present an algorithm for approximating semidefinite programs with running time that is sublinear in the number of entries in the semidefinite instance. We also present lower bounds that show our algorithm to have a nearly optimal running…

最优化与控制 · 数学 2012-08-28 Dan Garber , Elad Hazan

Sublinear time algorithms represent a new paradigm in computing, where an algorithm must give some sort of an answer after inspecting only a small portion of the input. The most typical situation where sublinear time algorithms are…

群论 · 数学 2011-05-18 Vladimir Shpilrain

We provide a deterministic algorithm that outputs an $O(n^{3/4} \log n)$-approximation for the Longest Common Subsequence (LCS) of two input sequences of length $n$ in near-linear time. This is the first deterministic approximation…

数据结构与算法 · 计算机科学 2025-07-31 Itai Boneh , Shay Golan , Matan Kraus

We give an algorithm that generates a uniformly random contingency table with specified marginals, i.e. a matrix with non-negative integer values and specified row and column sums. Such algorithms are useful in statistics and combinatorics.…

组合数学 · 数学 2021-06-17 Andrii Arman , Pu Gao , Nicholas Wormald

Detecting variation in the evolutionary process along chromosomes is increasingly important as whole-genome data becomes more widely available. For example, factors such as incomplete lineage sorting, horizontal gene transfer, and…

种群与进化 · 定量生物学 2017-01-03 Elizabeth S. Allman , Laura S. Kubatko , John A. Rhodes

We study the classical scheduling problem on parallel machines %with precedence constraints where the precedence graph has the bounded depth $h$. Our goal is to minimize the maximum completion time. We focus on developing approximation…

数据结构与算法 · 计算机科学 2023-02-02 Bin Fu , Yumei Huo , Hairong Zhao

Change-point problems have appeared in a great many applications for example cancer genetics, econometrics and climate change. Modern multiscale type segmentation methods are considered to be a statistically efficient approach for multiple…

统计计算 · 统计学 2018-05-04 Chengcheng Huang , Housen Li , Lizhi Cheng , Wei Peng

Executing various sequences of system functions in a system under test represents one of the primary techniques in software testing. The natural way to create effective, consistent and efficient test sequences is to model the system under…

软件工程 · 计算机科学 2019-12-05 Miroslav Bures , Bestoun S. Ahmed

The sparsest cut problem consists of identifying a small set of edges that breaks the graph into balanced sets of vertices. The normalized cut problem balances the total degree, instead of the size, of the resulting sets. Applications of…

社会与信息网络 · 计算机科学 2017-02-17 Arlei Silva , Ambuj Singh , Ananthram Swami

We describe a RAM algorithm computing all runs (maximal repetitions) of a given string of length $n$ over a general ordered alphabet in $O(n\log^{\frac{2}3} n)$ time and linear space. Our algorithm outperforms all known solutions working in…

数据结构与算法 · 计算机科学 2015-11-24 Dmitry Kosolobov

Leverage score sampling is crucial to the design of randomized algorithms for large-scale matrix problems, while the computation of leverage scores is a bottleneck of many applications. In this paper, we propose a quantum algorithm to…

量子物理 · 物理学 2023-09-19 Changpeng Shao

We consider the \textsf{Unit Interval Selection} problem in the one-pass random order streaming model. Here, an algorithm is presented a sequence of $n$ unit-length intervals on the line that arrive in uniform random order, and the…

数据结构与算法 · 计算机科学 2026-03-11 Cezar-Mihail Alexandru , Adithya Diddapur , Magnús M. Halldórsson , Christian Konrad , Kheeran K. Naidu

When trying to solve a computational problem, we are often faced with a choice between algorithms that are guaranteed to return the right answer but differ in their runtime distributions (e.g., SAT solvers, sorting algorithms). This paper…

人工智能 · 计算机科学 2023-06-06 Devon R. Graham , Kevin Leyton-Brown , Tim Roughgarden

This paper describes a method to efficiently retrieve protein database sequences similar to a query sequence, while allowing for significant numbers of mutations. We call this method SEQR for SEQuence Retrieval. This approach increases the…

基因组学 · 定量生物学 2018-11-05 David I. Hurwitz , Lianyi Han , Lewis Y. Geer

A valuable step in the modeling of multiscale dynamical systems in fields such as computational chemistry, biology, materials science and more, is the representative sampling of the phase space over long timescales of interest; this task is…

机器学习 · 计算机科学 2023-12-29 Ellis R. Crabtree , Juan M. Bello-Rivas , Ioannis G. Kevrekidis

The apportionment problem deals with the fair distribution of a discrete set of $k$ indivisible resources (such as legislative seats) to $n$ entities (such as parties or geographic subdivisions). Highest averages methods are a frequently…

数据结构与算法 · 计算机科学 2014-09-10 Zhanpeng Cheng , David Eppstein

The use of Hirschberg algorithm reduces the spatial cost of recovering the Longest Common Subsequence to linear space. The same technique can be applied to similar problems like Sequence Alignment. However, the price to pay is a duplication…

数据结构与算法 · 计算机科学 2022-04-28 David Llorens , Juan Miguel Vilar