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Excitatory synaptic connections in the adult neocortex consist of multiple synaptic contacts, almost exclusively formed on dendritic spines. Changes of dendritic spine shape and volume, a correlate of synaptic strength, can be tracked in…

神经元与认知 · 定量生物学 2018-03-13 Moritz Deger , Alexander Seeholzer , Wulfram Gerstner

Self-avoidance is a common mechanism to improve the efficiency of a random walker for covering a spatial domain. However, how this efficiency decreases when self-avoidance is impaired or limited by other processes has remained largely…

统计力学 · 物理学 2019-12-11 Daniel Campos , Javier Cristín , Vicenç Méndez

Neurons and networks in the cerebral cortex must operate reliably despite multiple sources of noise. To evaluate the impact of both input and output noise, we determine the robustness of single-neuron stimulus selective responses, as well…

神经元与认知 · 定量生物学 2018-01-24 Ran Rubin , L. F. Abbott , Haim Sompolinsky

Cortical neurons emit seemingly erratic trains of action potentials or "spikes," and neural network dynamics emerge from the coordinated spiking activity within neural circuits. These rich dynamics manifest themselves in a variety of…

神经元与认知 · 定量生物学 2022-04-01 Braden A. W. Brinkman , Han Yan , Arianna Maffei , Il Memming Park , Alfredo Fontanini , Jin Wang , Giancarlo La Camera

Experimental and numerical results suggest that the brain can be viewed as a system acting close to a critical point, as confirmed by scale-free distributions of relevant quantities in a variety of different systems and models. Less…

神经元与认知 · 定量生物学 2020-11-25 Dario Raimo , Alessandro Sarracino , Lucilla de Arcangelis

The behavior of the network and its stability are governed by both dynamics of individual nodes as well as their topological interconnections. Attention mechanism as an integral part of neural network models was initially designed for…

机器学习 · 计算机科学 2022-12-20 Nooshin Bahador , Milad Lankarany

In real-world networks the interactions between network elements are inherently time-delayed. These time-delays can not only slow the network but can have a destabilizing effect on the network's dynamics leading to poor performance. The…

最优化与控制 · 数学 2024-09-23 David Reber , Benjamin Webb

In this paper, a diffusion-based molecular communication channel between two nano-machines is considered. The effect of the amount of memory on performance is characterized, and a simple memory-limited decoder is proposed and its…

Using a realistic model of activity dependent dynamical synapses and a standard integrate and fire neuron model we study, both analytically and numerically, the conditions in which a postsynaptic neuron efficiently detects temporal…

神经元与认知 · 定量生物学 2007-05-23 Jorge F. Mejias , Joaquin J. Torres

Parkinson's disease (PD) is a neurodegenerative disorder characterized by increased response times leading to a variety of biomechanical symptoms such as tremors, stooping and gait instability. Although the deterioration in biomechanical…

定量方法 · 定量生物学 2017-07-27 Vrutangkumar Shah , Sachin Goyal , Harish Palanthandalam-Madapusi

The storage of continuous variables in working memory is hypothesized to be sustained in the brain by the dynamics of recurrent neural networks (RNNs) whose steady states form continuous manifolds. In some cases, it is thought that the…

神经元与认知 · 定量生物学 2023-10-31 Haggai Agmon , Yoram Burak

Various neurophysiological and cognitive functions are based on transferring information between spiking neurons via a complex system of synaptic connections. In particular, the capacity of presynaptic inputs to influence the postsynaptic…

神经元与认知 · 定量生物学 2018-10-30 Y. Dabaghian

In neural circuits, synaptic strengths influence neuronal activity by shaping network dynamics, and neuronal activity influences synaptic strengths through activity-dependent plasticity. Motivated by this fact, we study a recurrent-network…

神经元与认知 · 定量生物学 2024-01-12 David G. Clark , L. F. Abbott

Spiking Neural Networks (SNNs) are widely regarded as an energy-efficient paradigm for modeling and processing temporal and event-driven information. Incorporating delays in SNNs has been proven to be an effective mechanism for improving…

机器学习 · 计算机科学 2026-05-08 Dewei Bai , Hongxiang Peng , Yunyun Zeng , Ziyu Zhang , Hong Qu

We use a biophysical model of a local neuronal circuit to study the implications of synaptic plasticity for the detection of weak sensory stimuli. Networks with fast plastic coupling show behavior consistent with stochastic resonance.…

神经元与认知 · 定量生物学 2009-11-13 Vladislav Volman , Herbert Levine

In the cerebral cortex, neurons are subject to a continuous bombardment of synaptic inputs originating from the network's background activity. This leads to ongoing, mostly subthreshold membrane dynamics that depends on the statistics of…

生物物理 · 物理学 2009-11-07 Ulrich Hillenbrand

Competitive neural networks are often used to model the dynamics of perceptual bistability. Switching between percepts can occur through fluctuations and/or a slow adaptive process. Here, we analyze switching statistics in competitive…

神经元与认知 · 定量生物学 2012-12-05 Zachary P Kilpatrick

In modern neuroscience, memory has been postulated to stored in neural circuits as sequential spike train and Reverberation is one of the specific example.Former research has made much progress on phenomenon description. However, the…

神经元与认知 · 定量生物学 2022-11-29 Yi Ren , Yanyang Xiao , Guo-Qiang Bi , Pek-Ming Lau

Realizations of low firing rates in neural networks usually require globally balanced distributions among excitatory and inhibitory links, while feasibility of temporal coding is limited by neuronal millisecond precision. We show that…

神经元与认知 · 定量生物学 2015-06-16 Roni Vardi , Amir Goldental , Hagar Marmari , Haya Brama , Edward Stern , Shira Sardi , Pinhas Sabo , Ido Kanter

In Diffusive Molecular Communication (DMC), information is transmitted by diffusing molecules. Synaptic signaling is a natural implementation of this paradigm. It is responsible for relaying information from one neuron to another, but also…

亚细胞过程 · 定量生物学 2021-10-01 Sebastian Lotter , Arman Ahmadzadeh , Robert Schober