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Microscopic biological systems operate far from equilibrium, are subject to strong fluctuations, and are composed of many coupled components with interactions varying in nature and strength. Researchers are actively investigating the…

统计力学 · 物理学 2023-12-25 Emma Lathouwers , David A. Sivak

We consider the dynamics of a rigid filament in a motor protein assay under external loading. The motor proteins are modeled as active harmonic linkers with tail ends immobilized on a substrate. Their heads attach to the filament…

生物物理 · 物理学 2021-12-23 Amir Shee , Subhadip Ghosh , Debasish Chaudhuri

A simple model for the reaction-driven propulsion of a small device is proposed as a model for (part of) a molecular machine in aqueous media. Motion of the device is driven by an asymmetric distribution of reaction products. The propulsive…

软凝聚态物质 · 物理学 2009-11-13 Ramin Golestanian , Tanniemola B. Liverpool , Armand Ajdari

The transport by molecular motors along cytoskeletal filaments is studied theoretically in the presence of static defects. The movements of single motors are described as biased random walks along the filament as well as binding to and…

生物物理 · 物理学 2009-05-08 Yan Chai , Reinhard Lipowsky , Stefan Klumpp

A toy model is proposed which incorporates the reversible mode coupling mechanism responsible for ergodic-nonergodic transition with trivial Hamiltonian in the mode coupling theory (MCT) of structural glass transition. The model can be…

统计力学 · 物理学 2009-10-31 Kyozi Kawasaki , Bongsoo Kim

In recent literature there has been a lot of interest in the phenomena of noise induced transport in the absence of an average bias occurring in spatially periodic systems far from equilibrium. One of the main motivations in this area is to…

生物物理 · 物理学 2007-05-23 Raishma Krishnan , A. M. Jayannavar

The mobility of an overdamped particle, in a periodic potential tilted by a constant external field and moving in a medium with periodic friction coefficient is examined. When the potential and the friction coefficient have the same…

统计力学 · 物理学 2009-10-31 Debasis Dan , Mangal C. Mahato , A. M. Jayannavar

Intracellular cargos which are transported by molecular motors move stochastically along cytoskeleton filaments. In particular for bidirectionally transported cargos it is an open question whether the characteristics of their motion can…

生物物理 · 物理学 2017-09-20 Sarah Klein , Cecile Appert-Rolland , Ludger Santen

I describe a toy model of quantum measurement in which wave function collapse is described as a stochastic entropically-driven event guided by interactions between a measured two-state particle and an Ising-like measurement device. The…

综合物理 · 物理学 2023-12-14 Aaron Santos

Synthetic nanoscale complexes capable of mechanical movement are often studied theoretically using discrete-state models that involve instantaneous transitions between metastable states. A number of general results have been derived within…

统计力学 · 物理学 2012-12-21 Dibyendu Mandal , Christopher Jarzynski

Many cell functions are accomplished thanks to intracellular transport mechanisms of macromolecules along filaments. Molecular motors such as dynein or kinesin are proteins playing a primary role in these processes. The behavior of such…

混沌动力学 · 物理学 2010-12-21 Donatello Materassi , Subhrajit Roychowdhury , Murti V. Salapaka

We review the properties of biological motor proteins which move along linear filaments that are polar and periodic. The physics of the operation of such motors can be described by simple stochastic models which are coupled to a chemical…

生物物理 · 物理学 2009-10-31 Frank Julicher

Biological molecular motors are high-performance nanomachines that convert chemical energy into mechanical motion via chemomechanical coupling. Their reaction cycles typically comprise a series of intermediate chemical states between the…

生物物理 · 物理学 2025-05-26 Akihiro Fukuda , Yohei Nakayama , Shoichi Toyabe

In recent years, several artificial molecular motors driven and controlled by electric currents have been proposed. Similar to Brownian machines, these systems work by turning random inelastic tunneling events into a directional rotation of…

介观与纳米尺度物理 · 物理学 2022-10-31 Federico D. Ribetto , Sebastián E. Deghi , Hernán L. Calvo , Raúl A. Bustos-Marún

We investigate a microscopic motor based on an externally controlled two-level system. One cycle of the motor operation consists of two strokes. Within each stroke, the two-level system is in contact with a given thermal bath and its energy…

统计力学 · 物理学 2015-05-14 Petr Chvosta , Mario Einax , Viktor Holubec , Artem Ryabov , Philipp Maass

We model thermostatic devices using a stochastic hybrid description, and introduce an external actuation mechanism that creates random switch events in the discrete dynamics. We then conjecture the form of the Fokker-Planck equation and…

系统与控制 · 计算机科学 2015-01-27 Luminita Cristiana Totu , Rafael Wisniewski , John Leth

We show that the correlated stochastic fluctuation of the friction coefficient can give rise to long-range directional motion of a particle undergoing Brownian random walk in a constant periodic energy potential landscape. The occurrence of…

软凝聚态物质 · 物理学 2009-11-07 Lorenzo Marrucci , Domenico Paparo , Markus Kreuzer

A disordered version of the one dimensional asymmetric exclusion model where the particle hopping rates are quenched random variables is studied. The steady state is solved exactly by use of a matrix product. It is shown how the phenomenon…

凝聚态物理 · 物理学 2009-10-28 M. R. Evans

Particle transport through an open, discrete 1-D channel against a mechanical or chemical bias is analyzed within a master equation approach. The channel, externally driven by time dependent site energies, allows multiple occupation due to…

统计力学 · 物理学 2015-05-18 Mario Einax , Gemma Solomon , Wolfgang Dieterich , Abraham Nitzan

Manipulating and coupling molecule gears is the first step towards realizing molecular-scale mechanical machines. Here, we theoretically investigate the behavior of such gears using molecular dynamics simulations. Within a nearly rigid-body…

软凝聚态物质 · 物理学 2020-03-12 H. -H. Lin , A. Croy , R. Gutierrez , C. Joachim , G. Cuniberti