相关论文: A fast algorithm for backbones

Inverse protein folding -- the task of predicting a protein sequence from its backbone atom coordinates -- has surfaced as an important problem in the "top down", de novo design of proteins. Contemporary approaches have cast this problem as…

We mimic random nanowire networks by the homogeneous, isotropic, and random deposition of conductive zero-width sticks onto an insulating substrate. The number density (the number of objects per unit area of the surface) of these sticks is…

We propose a new method for shape recognition and retrieval based on dynamic programming. Our approach uses the dynamic programming algorithm to compute the optimal score and to find the optimal alignment between two strings. First, each…

Object Skeletonization is the process of extracting skeletal, line-like representations of shapes. It provides a very useful tool for geometric shape understanding and minimal shape representation. It also has a wide variety of…

General object detectors use powerful backbones that uniformly extract features from images for enabling detection of a vast amount of object types. However, utilization of such backbones in object detection applications developed for…

Continuum robots have emerged as a promising technology in the medical field due to their potential of accessing deep sited locations of the human body with low surgical trauma. When deriving physics-based models for these robots,…

Identifying local structural motifs and packing patterns of molecular solids is a challenging task for both simulation and experiment. We demonstrate two novel approaches to characterize local environments in different polymorphs of…

In order to investigate the dependence on lattice size of several observables in percolation, the Hoshen-Kopelman algorithm was modified so that growing lattices could be simulated. By this way, when simulating a lattice of size L, lattices…

Developments of nonlocal operators for modeling processes that traditionally have been described by local differential operators have been increasingly active during the last few years. One example is peridynamics for brittle materials and…

Similarity search is one of the most fundamental computations that are regularly performed on ever-increasing protein datasets. Scalability is of paramount importance for uncovering novel phenomena that occur at very large scales. We…

We study the statistics of the backbone cluster between two sites separated by distance $r$ in two-dimensional percolation networks subjected to spatial long-range correlations. We find that the distribution of backbone mass follows the…

Predicting the structure of multi-protein complexes is a grand challenge in biochemistry, with major implications for basic science and drug discovery. Computational structure prediction methods generally leverage pre-defined structural…

Reconstructing the 3D location and size of microparticles from diffraction images - holograms - is a computationally expensive inverse problem that has traditionally been solved using physics-based reconstruction methods. More recently,…

In an effort to explore high-throughput processing of microscopic image data, a method based on deep convolutional neural network is proposed. The state-of-the-art computer vision algorithm, Faster R-CNN, was trained for the detection of…

We describe new approaches for distances between pairs of 2-dimensional surfaces (embedded in 3-dimensional space) that use local structures and global information contained in inter-structure geometric relationships. We present algorithms…

The central problem of concern to Serrano, Boguna and Vespignani ("Extracting the multiscale backbone of complex weighted networks", Proc Natl Acad Sci 106:6483-6488 [2009]) can be effectively and elegantly addressed using a…

Fractal dimension is widely adopted in spatial databases and data mining, among others as a measure of dataset skewness. State-of-the-art algorithms for estimating the fractal dimension exhibit linear runtime complexity whether based on…

The backbone of a Boolean formula is the set of literals that must be true in every assignment that satisfies the formula. This concept is fundamental to key operations on variability models, including propagating user configuration…

Computational protein design has a wide variety of applications. Despite its remarkable success, designing a protein for a given structure and function is still a challenging task. On the other hand, the number of solved protein structures…

Model-based learned iterative reconstruction methods have recently been shown to outperform classical reconstruction algorithms. Applicability of these methods to large scale inverse problems is however limited by the available memory for…