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The generation of action potential brings into play specific mechanosensory stimuli manifest in the variation of membrane capacitance, resulting from the selective membrane permeability to ions exchanges and testifying to the central role…

神经元与认知 · 定量生物学 2021-02-23 Alain M. Dikande

Coherent superposition of electronic states, created by ionizing a molecule, can initiate ultrafast dynamics of the electron density. Correlation between nuclear and electron motions, however, typically dissipates the electronic coherence…

量子物理 · 物理学 2025-08-15 Alan Scheidegger , Nikolay V. Golubev , Jiri J. L. Vanicek

Tumor metastasis, traditionally considered as random spreading of individual cancer cells, has been shown to also involve coordinated collective invasion in the tissue space. Here we demonstrate experimentally and computationally that…

生物物理 · 物理学 2019-04-05 Jihan Kim , Yu Zheng , Amani A. Alobaidi , Hanqing Nan , Jianxiang Tian , Yang Jiao , Bo Sun

The response of cells during spreading and motility is dictated by several multi-physics events, which are triggered by extracellular cues and occur at different time-scales. For this sake, it is not completely appropriate to provide a cell…

软凝聚态物质 · 物理学 2020-11-26 M. Serpelloni , M. Arricca , C. Bonanno , A. Salvadori

Collagen fibers, an important component of the extracellular matrix (ECM), can both inhibit and promote cellular migration. {\it In-vitro} studies have revealed that the fibers' orientations are crucial to cellular invasion, while {\it…

细胞行为 · 定量生物学 2019-07-01 Youness Azimzade , Abbas Ali Saberi , Muhammad Sahimi

Cellular adaptation to environmental changes relies on the dynamic remodeling of subcellular structures. Among these, sarcomere structures are fundamental to the organization and function of the cytoskeletal architecture. In muscle-type…

细胞行为 · 定量生物学 2024-12-17 Yuika Ueda , Shinji Deguchi

A number of factors, such as, cell-cell interactions and self-propulsion of cells driven by cytoskeletal forces determine tissue morphologies and dynamics. To explore the interplay between these factors in controlling the dynamics at the…

软凝聚态物质 · 物理学 2025-05-12 Rajsekhar Das , Xin Li , Sumit Sinha , D. Thirumalai

Activity and renewability are distinctive features of living matter, and constitute a new class of materials that we term renewable active matter. A striking example is the cell cytoskeleton, where myosin filaments bind to the actin…

软凝聚态物质 · 物理学 2025-05-27 M. Abhishek , Ankit Dhanuka , Deb Sankar Banerjee , Madan Rao

Chemotaxis and haptotaxis have been a main theme in the macroscopic study of bacterial and cellular motility. In this work we investigate the influence these processes have on the shape and motility of fast migrating cells. We note that…

细胞行为 · 定量生物学 2016-12-08 Aaron Brunk , Niklas Kolbe , Nikolaos Sfakianakis

We present a general dynamical theory of a membrane coupled to an actin cortex containing polymerizing filaments with active stresses and currents, and demonstrate that active membrane dynamics [Phys. Rev. Lett \textbf{84}, 3494 (2000)] and…

生物物理 · 物理学 2015-06-18 Ananyo Maitra , Pragya Srivastava , Madan Rao , Sriram Ramaswamy

We study theoretically and numerically the coupling and rotational hydrodynamic interactions between spherical particles near a planar elastic membrane that exhibits resistance towards shear and bending. Using a combination of the multipole…

Using continuum elasticity theory, we describe the elastic behavior of helical coils with an asymmetric double-helix structure and identify conditions, under which they become very rigid. Theoretical insight gained for macro-structures…

软凝聚态物质 · 物理学 2017-06-13 David Tomanek , Arthur G. Every

Elastic confinements are an important component of many biological systems and dictate the transport properties of suspended particles under flow. In this chapter, we review the Brownian motion of a particle moving in the vicinity of a…

软凝聚态物质 · 物理学 2022-10-28 Abdallah Daddi-Moussa-Ider , Stephan Gekle

It is well known that lipid membranes respond to a threshold transmembrane electric field through a reversible mechanism called electroporation, where hydrophilic water pores form across the membrane, an effect widely used in biological…

软凝聚态物质 · 物理学 2023-04-17 Di Jin , Yu Zhang , Jacob Klein

Simulation of extracellular fields is one of the substantial methods used in the area of computational neuroscience. Its most common usage is validation of experimental methods as EEG and extracellular spike recordings or modeling of…

神经元与认知 · 定量生物学 2013-01-22 Pavol Bauer , Sanja Mikulovic , Stefan Engblom , Katarina E. Leão , Frank Rattay , Richardson N. Leão

When two periodic potentials compete in materials, one may adopt the other, which straightforwardly generates topological defects. Of particular interest are domain walls in charge-, dipole-, and spin-ordered systems, which govern…

强关联电子 · 物理学 2019-10-09 Jae Whan Park , Gil Young Cho , Jinwon Lee , Han Woong Yeom

The object of the present work is to study the quantum Hall effect through its symmetries and topological aspects. We consider the model of an electron moving in a two-dimensional lattice in the presence of applied in-plain electric field…

介观与纳米尺度物理 · 物理学 2009-11-10 A. Kunold , M. Torres

The primary building block of the body is collagen, which is found in the extracellular matrix and in many stress-bearing tissues such as tendon and cartilage. It provides elasticity and support to cells and tissues while influencing…

生物大分子 · 定量生物学 2019-07-29 Michael W. H. Kirkness , Kathrin Lehmann , Nancy R. Forde

Variations of transport efficiency in structured environments between distinct individuals in actively self-propelled systems is both hard to study and poorly understood. Here, we study the transport of a non-tumbling {\ecoli} strain, an…

软凝聚态物质 · 物理学 2023-08-28 Pooja Chopra , David Quint , Ajay Gopinathan , Bin Liu

The spontaneous generation of electrical activity underpins a number of essential physiological processes, and is observed even in tissues where specialized pacemaker cells have not been identified. The emergence of periodic oscillations in…

适应与自组织系统 · 物理学 2022-02-01 Ria Ghosh , Shakti N. Menon