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The protein folding problem must ultimately be solved on all length scales from the atomic up through a hierarchy of complicated structures. By analyzing the stability of the folding process using physics and mathematics, this paper shows…

生物物理 · 物理学 2015-05-28 Walter Simmons , Joel L. Weiner

The protein folding problem has attracted an increasing attention from physicists. The problem has a flavor of statistical mechanics, but possesses the most common feature of most biological problems -- the profound effects of evolution. I…

统计力学 · 物理学 2009-10-31 Chao Tang

Protein-protein binding enables orderly and lawful biological self-organization, and is therefore considered a miracle of nature. Protein-protein binding is steered by electrostatic forces, hydrogen bonding, van der Waals force, and…

生物大分子 · 定量生物学 2022-02-23 Lin Yang , Shuai Guo , Chengyu Hou , Chencheng Liao , Jiacheng Li , Liping Shi , Xiaoliang Ma , Shenda Jiang , Bing Zheng , Yi Fang , Lin Ye , Xiaodong He

Spilling tea or coffee leads to a tell-tale circular stain after the droplet dries, known as the "coffee ring effect". The evaporation of suspension droplets is a complex physical process, and predicting and controlling the particle deposit…

Superhydrophobicity relies on the stability of drops's interfaces pinned on sharp edges to sustain non-wetting (Cassie-Baxter) equilibrium states. Gibbs already pointed out that equilibrium is possible as long as the pinning angle at the…

流体动力学 · 物理学 2019-08-26 José Graña Otero , Ignacio E. Parra Fabián

Controlling the motion of non-Newtonian drops on surfaces is crucial for applications ranging from inkjet printing to biomedical devices and food processing. While the macroscopic behavior of viscoelastic drops sliding on tilted hydrophobic…

Crystallography may be the gold standard of protein structure determination, but obtaining the necessary high-quality crystals is also in some ways akin to prospecting for the precious metal. The tools and models developed in soft matter…

软凝聚态物质 · 物理学 2016-02-10 Diana Fusco , Patrick Charbonneau

Particles confined in droplets are called compound particles. They are encountered in various biological and soft matter systems. Hydrodynamics can play a decisive role in determining the configuration and stability of these multiphase…

软凝聚态物质 · 物理学 2019-08-23 Sravana Chaithanya , Sumesh P Thampi

We investigate contact angle hysteresis on chemically patterned and superhydrophobic surfaces, as the drop volume is quasi-statically increased and decreased. We consider both two, and three, dimensions using analytical and numerical…

软凝聚态物质 · 物理学 2008-03-12 H. Kusumaatmaja , J. M. Yeomans

We study fully three-dimensional droplets that slide down an incline by employing a thin-film equation that accounts for capillarity, wettability, and a lateral driving force in small-gradient (or long-wave) approximation. In particular, we…

流体动力学 · 物理学 2016-12-15 Sebastian Engelnkemper , Markus Wilczek , Svetlana V. Gurevich , Uwe Thiele

Making use of a simplified model for protein folding, it can be shown that conformations which are particularly stable when their energy is minimized with respect to amino acid sequence (in the sense that they display a large energy gap to…

软凝聚态物质 · 物理学 2007-05-23 R. A. Broglia , G. Tiana , H. E. Roman

We present a fluid dynamics video showing the adhesion of a drop to a superhydrophobic surface. We use environmental scanning electron microscopy to observe depinning events at the microscale. As the drop moves along the surface, the…

流体动力学 · 物理学 2013-10-16 Adam T. Paxson , Kripa K. Varanasi

The evaporation of a droplet induces variety of ordered patterns near the contact line between the droplet and a substrate. This pattern formation involves both the behavior of colloidal suspensions and interactions between a droplet and a…

软凝聚态物质 · 物理学 2024-08-05 Yusaku Abe , Yu Matsuda

The evaporation of drops of colloidal suspensions plays an important role in numerous contexts, such as the production of powdered dairies, the synthesis of functional supraparticles, and virus and bacteria survival in aerosols or drops on…

软凝聚态物质 · 物理学 2023-09-25 Milani M , Phou T , Ligoure C , Cipelletti L , Ramos L

We discuss crystal formation in supersaturated suspensions of monodisperse hard spheres with a concentration of hard spheres randomly pinned in space and time. The pinning procedure introduces an external length scale and an external time…

统计力学 · 物理学 2013-10-01 Sven Dorosz , Tanja Schilling

Light localization and intensity enhancement in a woodpile layer-by-layer photonic crystal, whose interlayer distance along the propagation direction is gradually varied, has been theoretically predicted and experimentally demonstrated. The…

光学 · 物理学 2017-07-17 Zeki Hayran , Hamza Kurt , Kestutis Staliunas

Protein crystal production is a major bottleneck for the structural characterisation of proteins. To advance beyond large-scale screening, rational strategies for protein crystallization are crucial. Understanding how chemical anisotropy…

生物大分子 · 定量生物学 2022-05-03 Amir R. Khan , Susan James , Michelle K. Quinn , Irem Altan , Patrick Charbonneau , Jennifer J. McManus

We experimentally investigate the splashing mechanism of a millimeter-sized ethanol drop impinging on a structured solid surface, comprised of micro-pillars, through side-view and top-view high speed imaging. By increasing the impact…

流体动力学 · 物理学 2010-10-20 Peichun Tsai , Roeland van der Veen , Matthias van de Raa , Detlef Lohse

We present a molecular dynamics study of the motion of cylindrical polymer droplets on striped surfaces. We first consider the equilibrium properties of droplets on different surfaces, we show that for small stripes the Cassie-Baxter…

软凝聚态物质 · 物理学 2019-08-28 Ozlem Ozturk , James Servantie

Pendant drops suspended on the underside of a wet substrate are known to accumulate fluid from the surrounding thin liquid film, a process that often results in dripping. The growth of such drops is hastened by their ability to translate…

流体动力学 · 物理学 2021-08-02 Etienne Jambon-Puillet , Pier Giuseppe Ledda , François Gallaire , P. -T. Brun