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Single receptor-ligand bonds have finite lifetimes, so that biological systems can dynamically react to changes in their environment. In cell adhesion, adhesion bonds usually act cooperatively in adhesion clusters. Outside the cellular…

软凝聚态物质 · 物理学 2007-05-23 T. Erdmann , U. S. Schwarz

We solve the stochastic equations for a cluster of parallel bonds with shared constant loading, rebinding and the completely dissociated state as an absorbing boundary. In the small force regime, cluster lifetime grows only logarithmically…

软凝聚态物质 · 物理学 2007-05-23 T. Erdmann , U. S. Schwarz

Biological adhesion often involves several pairs of specific receptor-ligand molecules. Using rate equations, we study theoretically the rupture of such multiple parallel bonds under dynamic loading assisted by thermal activation. For a…

生物物理 · 物理学 2009-11-06 Udo Seifert

Adhesion interactions mediated by multiple bond types are relevant for many biological and soft matter systems, including the adhesion of biological cells and functionalized colloidal particles to various substrates. To elucidate advantages…

生物物理 · 物理学 2020-10-21 Anil K. Dasanna , Gerhard Gompper , Dmitry A. Fedosov

In biological materials, strong binding despite an applied load force is often based on clusters of dynamic bonds that share the load. Different macroscopic behaviors have been described depending on whether the load is shared locally or…

生物物理 · 物理学 2025-09-11 Yannick Lüdemann , Stefan Klumpp , Komal Bhattacharyya

We present a general stochastic dynamic model of a cluster of biological complexes with fluctuating dissociation and association rates. The master equation has analytical solutions in two limiting cases: the vanishing force with reflecting…

软凝聚态物质 · 物理学 2007-05-23 Fei Liu , Zhong-can Ou-Yang

The strength of a simple soft bond under constant loading rate is studied theoretically. We find a scaling regime where rebinding is negligible and the rupture force of the bond scales as $const. + (\ln (kv))^{2/3}$, where $kv$ is the…

软凝聚态物质 · 物理学 2007-05-23 Hsuan-Yi Chen , Yi-Ping Chu

We study the existence of distinct failure regimes in a model for fracture in fibrous materials. We simulate a bundle of parallel fibers under uniaxial static load and observe two different failure regimes: a catastrophic and a slowly…

统计力学 · 物理学 2015-06-24 I. L. Menezes-Sobrinho , J. G. Moreira , A. T. Bernardes

We simulate the collision of atomic clusters with a weakly attractive surface using molecular dynamics in a regime between soft-landing and fragmentation, where the cluster undergoes large deformation but remains intact. As a function of…

材料科学 · 物理学 2007-05-23 A. Awasthi , S. C. Hendy , P. Zoontjens , S. A. Brown

We consider the rupture dynamics of a homopolymer chain pulled at one end at a constant loading rate r. Compared to single bond breaking, the existence of the chain introduces two new aspects into rupture dynamics: the non-Markovian aspect…

软凝聚态物质 · 物理学 2009-10-29 S. Fugmann , I. M. Sokolov

The geometry of fracture patterns in a dilute elastic network is explored using molecular dynamics simulation. The network in two dimensions is subjected to a uniform strain which drives the fracture to develop by the growth and coalescence…

凝聚态物理 · 物理学 2015-06-25 P. Ray , G. Date

We present results of simulations for a dilute gas of inelastically colliding particles. Collisions are modelled as a stochastic process, which on average decreases the translational energy (cooling), but allows for fluctuations in the…

统计力学 · 物理学 2009-10-30 Timo Aspelmeier , Götz Giese , Annette Zippelius

The random-cluster model, a correlated bond percolation model, unifies a range of important models of statistical mechanics in one description, including independent bond percolation, the Potts model and uniform spanning trees. By…

统计力学 · 物理学 2016-01-28 Eren Metin Elçi , Martin Weigel , Nikolaos G. Fytas

We investigate a class of stochastic aggregation processes involving two types of clusters: active and passive. The mass distribution is obtained analytically for several aggregation rates. When the aggregation rate is constant, we find…

统计力学 · 物理学 2007-05-23 P. L. Krapivsky , E. Ben-Naim

The structure and mechanical properties of a simple two-dimensional model of a cohesive powder are investigated by molecular dynamics simulations. Micromechanical ingredients involve elasticity, friction, a short range attraction and,…

无序系统与神经网络 · 物理学 2007-05-24 Francisco Gilabert , Jean-Noel Roux , Antonio Castellanos

We study the creep rupture of bundles of viscoelastic fibers occurring under uniaxial constant tensile loading. A novel fiber bundle model is introduced which combines the viscoelastic constitutive behaviour and the strain controlled…

统计力学 · 物理学 2019-05-15 Raul Cruz Hidalgo , Ferenc Kun , Hans. J. Herrmann

The compressive yield stress of particle gels shows a highly nonlinear dependence on the packing fraction. We have studied continuous compression processes, and discussed the packing fraction dependence with the particle scale…

软凝聚态物质 · 物理学 2013-11-22 Ryohei Seto , Robert Botet , Martine Meireles , Günter K. Auernhammer , Bernard Cabane

It is shown that a compound elastic structure, which displays a dynamic instability, may be designed as the union (or 'fusion') of two structures which are stable when separately analyzed. The compound elastic structure has two degrees of…

经典物理 · 物理学 2023-01-16 Marco Rossi , Andrea Piccolroaz , Davide Bigoni

The quasistatic behavior of a simple 2D model of a cohesive powder under isotropic loads is investigated by Discrete Element simulations. The loose packing states, as studied in a previous paper, undergo important structural changes under…

材料科学 · 物理学 2008-10-27 Francisco Gilabert , Jean-Noël Roux , Antonio Castellanos

We consider a microscopic model for the failure of soft adhesives in tension based on ideas of bond rupture under dynamic loading. Focusing on adhesive failure under loading at constant velocity, we demonstrate that bi-modal curves of…

软凝聚态物质 · 物理学 2007-05-23 Dominic Vella , L. Mahadevan
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