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Multimodal molecular representation learning, which jointly models molecular graphs and their textual descriptions, enhances predictive accuracy and interpretability by enabling more robust and reliable predictions of drug toxicity,…

机器学习 · 计算机科学 2025-10-21 Yingxu Wang , Kunyu Zhang , Jiaxin Huang , Nan Yin , Siwei Liu , Eran Segal

Single-Domain Generalized Object Detection~(S-DGOD) aims to train an object detector on a single source domain while generalizing well to diverse unseen target domains, making it suitable for multimedia applications that involve various…

计算机视觉与模式识别 · 计算机科学 2025-04-29 Xiaoran Xu , Jiangang Yang , Wenyue Chong , Wenhui Shi , Shichu Sun , Jing Xing , Jian Liu

Introspection of deep supervised predictive models trained on functional and structural brain imaging may uncover novel markers of Alzheimer's disease (AD). However, supervised training is prone to learning from spurious features (shortcut…

Text-to-shape retrieval is an increasingly relevant problem with the growth of 3D shape data. Recent work on contrastive losses for learning joint embeddings over multimodal data has been successful at tasks such as retrieval and…

计算机视觉与模式识别 · 计算机科学 2023-12-29 Yue Ruan , Han-Hung Lee , Yiming Zhang , Ke Zhang , Angel X. Chang

Drug--target affinity prediction is pivotal for accelerating drug discovery, yet existing methods suffer from significant performance degradation in realistic cold-start scenarios (unseen drugs/targets/pairs), primarily driven by…

机器学习 · 计算机科学 2026-03-17 Zihan Dun , Liuyi Xu , An-Yang Lu , Shuang Li , Yining Qian

This paper addresses the challenges in representation learning of 3D shape features by investigating state-of-the-art backbones paired with both contrastive supervised and self-supervised learning objectives. Computer vision methods…

Feature matching is a cornerstone task in computer vision, essential for applications such as image retrieval, stereo matching, 3D reconstruction, and SLAM. This survey comprehensively reviews modality-based feature matching, exploring…

计算机视觉与模式识别 · 计算机科学 2025-07-31 Weide Liu , Wei Zhou , Jun Liu , Ping Hu , Jun Cheng , Jungong Han , Weisi Lin

Histopathology remains the gold standard for cancer diagnosis and prognosis. With the advent of transcriptome profiling, multi-modal learning combining transcriptomics with histology offers more comprehensive information. However, existing…

图像与视频处理 · 电气工程与系统科学 2026-03-03 Yupei Zhang , Xiaofei Wang , Anran Liu , Lequan Yu , Chao Li

Interaction between pharmacological agents can trigger unexpected adverse events. Capturing richer and more comprehensive information about drug-drug interactions (DDI) is one of the key tasks in public health and drug development.…

机器学习 · 计算机科学 2020-10-19 Yuanfei Dai , Chenhao Guo , Wenzhong Guo , Carsten Eickhoff

Multi-object tracking (MOT) and trajectory prediction are two critical components in modern 3D perception systems that require accurate modeling of multi-agent interaction. We hypothesize that it is beneficial to unify both tasks under one…

计算机视觉与模式识别 · 计算机科学 2021-04-06 Xinshuo Weng , Ye Yuan , Kris Kitani

Drug combination therapy has become a increasingly promising method in the treatment of cancer. However, the number of possible drug combinations is so huge that it is hard to screen synergistic drug combinations through wet-lab…

机器学习 · 计算机科学 2021-07-07 J. Wang , X. Liu , S. Shen , L. Deng , H. Liu*

Multimodal deep learning holds promise for improving clinical prediction by integrating diverse patient data, including text, imaging, time-series, and structured demographics. Contrastive learning facilitates this integration by producing…

机器学习 · 计算机科学 2025-07-08 Michal Golovanevsky , Pranav Mahableshwarkar , Carsten Eickhoff , Ritambhara Singh

Knowledge distillation (KD) has been widely studied in unsupervised image Anomaly Detection (AD), but its application to unsupervised multimodal AD remains underexplored. Existing KD-based methods for multimodal AD that use fused multimodal…

计算机视觉与模式识别 · 计算机科学 2025-07-28 Xinyue Liu , Jianyuan Wang , Biao Leng , Shuo Zhang

Detecting trajectory anomalies is a vital task in modern Intelligent Transportation Systems (ITS), enabling the identification of unsafe, inefficient, or irregular travel behaviours. While deep learning has emerged as the dominant approach,…

机器学习 · 计算机科学 2025-11-24 Rui Xue , Dan He , Fengmei Jin , Chen Zhang , Xiaofang Zhou

Existing works based on molecular knowledge neglect the 3D geometric structure of molecules and fail to learn the high-dimensional information of medications, leading to structural confusion. Additionally, it does not extract key…

机器学习 · 计算机科学 2024-11-13 Shi Mu , Chen Li , Xiang Li , Shunpan Liang

In autonomous driving, LiDAR point-clouds and RGB images are two major data modalities with complementary cues for 3D object detection. However, it is quite difficult to sufficiently use them, due to large inter-modal discrepancies. To…

计算机视觉与模式识别 · 计算机科学 2022-04-05 Yanan Zhang , Jiaxin Chen , Di Huang

Accurate and robust drug response prediction is of utmost importance in precision medicine. Although many models have been developed to utilize the representations of drugs and cancer cell lines for predicting cancer drug responses (CDR),…

定量方法 · 定量生物学 2023-11-22 Xiaoqiong Xia , Chaoyu Zhu , Yuqi Shan , Fan Zhong , Lei Liu

Virtual screening, which identifies potential drugs from vast compound databases to bind with a particular protein pocket, is a critical step in AI-assisted drug discovery. Traditional docking methods are highly time-consuming, and can only…

机器学习 · 计算机科学 2023-10-11 Bowen Gao , Bo Qiang , Haichuan Tan , Minsi Ren , Yinjun Jia , Minsi Lu , Jingjing Liu , Weiying Ma , Yanyan Lan

In recent years, the use of edge information provided by knowledge graphs together with the advantages of higher-order connectivity in graph neural networks for recommendation systems has become an important research direction. However,…

信息检索 · 计算机科学 2026-05-12 Zhifei Hu , Feng Xia

Magnetic resonance diffusion tensor imaging (DTI) is a critical tool for neural disease diagnosis. However, long scan time greatly hinders the widespread clinical use of DTI. To accelerate image acquisition, a feature-enhanced joint…

图像与视频处理 · 电气工程与系统科学 2024-05-28 Lang Zhang , Jinling He , Dong Liang , Hairong Zheng , Yanjie Zhu
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