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Advances in medical imaging and deep learning have propelled progress in whole slide image (WSI) analysis, with multiple instance learning (MIL) showing promise for efficient and accurate diagnostics. However, conventional MIL models often…

计算机视觉与模式识别 · 计算机科学 2025-05-19 Xianrui Li , Yufei Cui , Jun Li , Antoni B. Chan

Multi-Instance Learning (MIL) is pivotal for analyzing complex, weakly labeled datasets, such as whole-slide images (WSIs) in computational pathology, where bags comprise unordered collections of instances with sparse diagnostic relevance.…

计算机视觉与模式识别 · 计算机科学 2025-09-16 Yuedi Zhang , Zhixiang Xia , Guosheng Yin , Bin Liu

Classical multiple instance learning (MIL) methods are often based on the identical and independent distributed assumption between instances, hence neglecting the potentially rich contextual information beyond individual entities. On the…

计算机视觉与模式识别 · 计算机科学 2022-06-20 Daniel Reisenbüchler , Sophia J. Wagner , Melanie Boxberg , Tingying Peng

Timely and accurate diagnosis of appendicitis is critical in clinical settings to prevent serious complications. While CT imaging remains the standard diagnostic tool, the growing number of cases can overwhelm radiologists, potentially…

计算机视觉与模式识别 · 计算机科学 2025-07-01 Chia-Wen Huang , Haw Hwai , Chien-Chang Lee , Pei-Yuan Wu

Convolutional neural networks (CNN) have achieved state of the art performance on both classification and segmentation tasks. Applying CNNs to microscopy images is challenging due to the lack of datasets labeled at the single cell level. We…

计算机视觉与模式识别 · 计算机科学 2017-05-25 Oren Z. Kraus , Lei Jimmy Ba , Brendan Frey

Objective: Medical image datasets with pixel-level labels tend to have a limited number of organ or tissue label classes annotated, even when the images have wide anatomical coverage. With supervised learning, multiple classifiers are…

Whole Slide Images (WSIs) are high-resolution digital scans widely used in medical diagnostics. WSI classification is typically approached using Multiple Instance Learning (MIL), where the slide is partitioned into tiles treated as…

计算机视觉与模式识别 · 计算机科学 2025-11-25 Sharon Peled , Yosef E. Maruvka , Moti Freiman

Hispathological image segmentation algorithms play a critical role in computer aided diagnosis technology. The development of weakly supervised segmentation algorithm alleviates the problem of medical image annotation that it is…

计算机视觉与模式识别 · 计算机科学 2022-05-19 Ziniu Qian , Kailu Li , Maode Lai , Eric I-Chao Chang , Bingzheng Wei , Yubo Fan , Yan Xu

We propose an end-to-end-trainable attention module for convolutional neural network (CNN) architectures built for image classification. The module takes as input the 2D feature vector maps which form the intermediate representations of the…

计算机视觉与模式识别 · 计算机科学 2018-05-01 Saumya Jetley , Nicholas A. Lord , Namhoon Lee , Philip H. S. Torr

Multiple Instance Learning (MIL) effectively analyzes whole slide images but faces overfitting due to attention over-concentration. While existing solutions rely on complex architectural modifications or additional processing steps, we…

计算机视觉与模式识别 · 计算机科学 2025-07-01 Yunlong Zhang , Honglin Li , Yunxuan Sun , Zhongyi Shui , Jingxiong Li , Chenglu Zhu , Lin Yang

Multiple Instance Learning is the predominant method for Whole Slide Image classification in digital pathology, enabling the use of slide-level labels to supervise model training. Although MIL eliminates the tedious fine-grained annotation…

计算机视觉与模式识别 · 计算机科学 2025-05-28 Chen Shu , Boyu Fu , Yiman Li , Ting Yin , Wenchuan Zhang , Jie Chen , Yuhao Yi , Hong Bu

Whole slide images, with their gigapixel-scale panoramas of tissue samples, are pivotal for precise disease diagnosis. However, their analysis is hindered by immense data size and scarce annotations. Existing MIL methods face challenges due…

计算机视觉与模式识别 · 计算机科学 2026-02-26 Weiyi Wu , Xinwen Xu , Chongyang Gao , Xingjian Diao , Siting Li , Jiang Gui

Multi-instance learning (MIL) is a form of weakly supervised learning where a single class label is assigned to a bag of instances while the instance-level labels are not available. Training classifiers to accurately determine the bag label…

计算机视觉与模式识别 · 计算机科学 2020-06-11 Bin Li , Kevin W. Eliceiri

Weakly supervised whole slide image classification is usually formulated as a multiple instance learning (MIL) problem, where each slide is treated as a bag, and the patches cut out of it are treated as instances. Existing methods either…

计算机视觉与模式识别 · 计算机科学 2024-05-14 Linhao Qu , Yingfan Ma , Xiaoyuan Luo , Manning Wang , Zhijian Song

The scalability of current language-image pre-training for 3D medical imaging, such as CT and MRI, is constrained by the need for radiologists to manually curate raw clinical studies. In this work, we pioneer pre-training directly on…

计算机视觉与模式识别 · 计算机科学 2026-02-20 Chenhui Zhao , Yiwei Lyu , Asadur Chowdury , Edward Harake , Akhil Kondepudi , Akshay Rao , Xinhai Hou , Honglak Lee , Todd Hollon

Multiple instance learning (MIL) is a powerful tool to solve the weakly supervised classification in whole slide image (WSI) based pathology diagnosis. However, the current MIL methods are usually based on independent and identical…

计算机视觉与模式识别 · 计算机科学 2021-11-02 Zhuchen Shao , Hao Bian , Yang Chen , Yifeng Wang , Jian Zhang , Xiangyang Ji , Yongbing Zhang

A large portion of volumetric medical data, especially magnetic resonance imaging (MRI) data, is anisotropic, as the through-plane resolution is typically much lower than the in-plane resolution. Both 3D and purely 2D deep learning-based…

图像与视频处理 · 电气工程与系统科学 2023-11-29 Alex Ling Yu Hung , Haoxin Zheng , Kai Zhao , Xiaoxi Du , Kaifeng Pang , Qi Miao , Steven S. Raman , Demetri Terzopoulos , Kyunghyun Sung

In the application of Multiple Instance Learning (MIL) methods for Whole Slide Image (WSI) classification, attention mechanisms often focus on a subset of discriminative instances, which are closely linked to overfitting. To mitigate…

计算机视觉与模式识别 · 计算机科学 2024-07-08 Yunlong Zhang , Honglin Li , Yuxuan Sun , Sunyi Zheng , Chenglu Zhu , Lin Yang

Even though convolutional neural networks (CNNs) are driving progress in medical image segmentation, standard models still have some drawbacks. First, the use of multi-scale approaches, i.e., encoder-decoder architectures, leads to a…

计算机视觉与模式识别 · 计算机科学 2020-02-18 Ashish Sinha , Jose Dolz

Medical image segmentation is a key task in the imaging workflow, influencing many image-based decisions. Traditional, fully-supervised segmentation models rely on large amounts of labeled training data, typically obtained through manual…

计算机视觉与模式识别 · 计算机科学 2024-12-12 Tyler Ward , Abdullah-Al-Zubaer Imran