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Multimodal survival prediction, a crucial yet challenging task, demands the integration of multimodal medical data (\eg Whole Slide Images (WSIs) and Genomic Profiles) to achieve accurate prognostic modeling. Given the inherent…

计算机视觉与模式识别 · 计算机科学 2026-05-21 Huayi Wang , Haochao Ying , Yuyang Xu , Qiyao Zheng , jun wang , Cheng Zhang , Ying Sun , Jian Wu

Survival analysis, as a challenging task, requires integrating Whole Slide Images (WSIs) and genomic data for comprehensive decision-making. There are two main challenges in this task: significant heterogeneity and complex inter- and…

图像与视频处理 · 电气工程与系统科学 2024-06-17 Conghao Xiong , Hao Chen , Hao Zheng , Dong Wei , Yefeng Zheng , Joseph J. Y. Sung , Irwin King

Mixture-of-Experts (MoE) is a flexible framework that combines multiple specialized submodels (``experts''), by assigning covariate-dependent weights (``gating functions'') to each expert, and have been commonly used for analyzing…

统计方法学 · 统计学 2026-01-06 Qicheng Zhao , Celia M. T. Greenwood , Qihuang Zhang

AI-based models for histopathology whole slide image (WSI) analysis are increasingly common, but unsharp or blurred areas within WSI can significantly reduce prediction performance. In this study, we investigated the effect of image blur on…

图像与视频处理 · 电气工程与系统科学 2025-07-21 Yujie Xiang , Bojing Liu , Mattias Rantalainen

Integrating the different data modalities of cancer patients can significantly improve the predictive performance of patient survival. However, most existing methods ignore the simultaneous utilization of rich semantic features at different…

计算机视觉与模式识别 · 计算机科学 2024-05-14 Liangrui Pan , Yijun Peng , Yan Li , Yiyi Liang , Liwen Xu , Qingchun Liang , Shaoliang Peng

The objective of this paper is to provide a baseline for performing multi-modal data classification on a novel open multimodal dataset of hepatocellular carcinoma (HCC), which includes both image data (contrast-enhanced CT and MRI images)…

Benefiting from the advancements in deep learning, various genomic analytical techniques, such as survival analysis, classification of tumors and their subtypes, and exploration of specific pathways, have significantly enhanced our…

机器学习 · 计算机科学 2023-12-19 Xiangyu Meng , Xue Li , Qing Yang , Huanhuan Dai , Lian Qiao , Hongzhen Ding , Long Hao , Xun Wang

Cancer survival analysis commonly integrates information across diverse medical modalities to make survival-time predictions. Existing methods primarily focus on extracting different decoupled features of modalities and performing fusion…

计算机视觉与模式识别 · 计算机科学 2026-02-25 Huayi Wang , Haochao Ying , Yuyang Xu , Qibo Qiu , Cheng Zhang , Danny Z. Chen , Ying Sun , Jian Wu

Cancer diagnosis, prognosis, and therapeutic response predictions are based on morphological information from histology slides and molecular profiles from genomic data. However, most deep learning-based objective outcome prediction and…

计算机视觉与模式识别 · 计算机科学 2020-09-04 Richard J. Chen , Ming Y. Lu , Jingwen Wang , Drew F. K. Williamson , Scott J. Rodig , Neal I. Lindeman , Faisal Mahmood

Healthcare models are transitioning from unimodal prediction toward multimodal reasoning over heterogeneous diagnostic inputs. In computational pathology, for complex tumor subtypes where morphology alone can be challenging to distinguish,…

Accurately predicting the survival rate of cancer patients is crucial for aiding clinicians in planning appropriate treatment, reducing cancer-related medical expenses, and significantly enhancing patients' quality of life. Multimodal…

计算机视觉与模式识别 · 计算机科学 2024-03-15 Liangrui Pan , Yijun Peng , Yan Li , Xiang Wang , Wenjuan Liu , Liwen Xu , Qingchun Liang , Shaoliang Peng

In this study, we propose MoME, a Mixture of Visual Language Medical Experts, for Medical Image Segmentation. MoME adapts the successful Mixture of Experts (MoE) paradigm, widely used in Large Language Models (LLMs), for medical…

计算机视觉与模式识别 · 计算机科学 2025-11-03 Arghavan Rezvani , Xiangyi Yan , Anthony T. Wu , Kun Han , Pooya Khosravi , Xiaohui Xie

Survival prediction is a crucial task associated with cancer diagnosis and treatment planning. This paper presents a novel approach to survival prediction by harnessing comprehensive information from CT and PET scans, along with associated…

图像与视频处理 · 电气工程与系统科学 2024-10-01 Aiman Farooq , Deepak Mishra , Santanu Chaudhury

Deep mixture-of-experts models have attracted a lot of attention for survival analysis problems, particularly for their ability to cluster similar patients together. In practice, grouping often comes at the expense of key metrics such as…

机器学习 · 计算机科学 2025-11-25 Todd Morrill , Aahlad Puli , Murad Megjhani , Soojin Park , Richard Zemel

Survival prediction for esophageal squamous cell cancer (ESCC) is crucial for doctors to assess a patient's condition and tailor treatment plans. The application and development of multi-modal deep learning in this field have attracted…

图像与视频处理 · 电气工程与系统科学 2024-08-27 Chengyu Wu , Yatao Zhang , Yaqi Wang , Qifeng Wang , Shuai Wang

Foundation models for medical image segmentation have achieved remarkable performance. Adaptive fine-tuning of natural image segmentation foundation models is crucial for medical image segmentation tasks. However, some limitations exist in…

计算机视觉与模式识别 · 计算机科学 2025-10-21 Xinwei Zhang , Hu Chen , Zhe Yuan , Sukun Tian , Peng Feng

The complementary information found in different modalities of patient data can aid in more accurate modelling of a patient's disease state and a better understanding of the underlying biological processes of a disease. However, the…

Breast cancer is a significant health concern affecting millions of women worldwide. Accurate survival risk stratification plays a crucial role in guiding personalised treatment decisions and improving patient outcomes. Here we present…

计算机视觉与模式识别 · 计算机科学 2024-07-02 Raktim Kumar Mondol , Ewan K. A. Millar , Arcot Sowmya , Erik Meijering

Covariance matrices arise naturally in different scientific fields, including finance, genomics, and neuroscience, where they encode dependence structures and reveal essential features of complex multivariate systems. In this work, we…

统计方法学 · 统计学 2026-02-17 The Tien Mai , Zhi Zhao

Survival analysis is a task to model the time until an event of interest occurs, widely used in clinical and biomedical research. A key challenge is to model patient heterogeneity while also adapting risk predictions to both individual…

机器学习 · 计算机科学 2025-10-31 Hyeonjun Lee , Hyungseob Shin , Gunhee Nam , Hyeonsoo Lee
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