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相关论文: Benchmarking Pathology Foundation Models for Spati…

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Pathology foundation models learn morphological representations through self-supervised pretraining on large-scale whole-slide images, yet they do not explicitly capture the underlying molecular state of the tissue. Spatial transcriptomics…

计算机视觉与模式识别 · 计算机科学 2026-03-10 Minsoo Lee , Jonghyun Kim , Juseung Yun , Sunwoo Yu , Jongseong Jang

The rapid generation of whole-slide images (WSIs) in dermatopathology necessitates automated methods for efficient processing and accurate classification. This study evaluates the performance of two foundation models, UNI and Virchow2, as…

计算机视觉与模式识别 · 计算机科学 2025-10-27 Riya Gupta , Yiwei Zong , Dennis H. Murphree

Representation learning of pathology whole-slide images (WSIs) has been has primarily relied on weak supervision with Multiple Instance Learning (MIL). However, the slide representations resulting from this approach are highly tailored to…

计算机视觉与模式识别 · 计算机科学 2024-05-21 Andrew H. Song , Richard J. Chen , Tong Ding , Drew F. K. Williamson , Guillaume Jaume , Faisal Mahmood

Recent breakthroughs in self-supervised learning have enabled the use of large unlabeled datasets to train visual foundation models that can generalize to a variety of downstream tasks. While this training paradigm is well suited for the…

Graph foundation models (GFM) aim to acquire transferable knowledge by pre-training on diverse graphs, which can be adapted to various downstream tasks. However, domain shift in graphs is inherently two-dimensional: graphs differ not only…

计算与语言 · 计算机科学 2026-03-12 Xingtong Yu , Shenghua Ye , Ruijuan Liang , Chang Zhou , Hong Cheng , Xinming Zhang , Yuan Fang

Pathological image segmentation faces numerous challenges, particularly due to ambiguous semantic boundaries and the high cost of pixel-level annotations. Although recent semi-supervised methods based on consistency regularization (e.g.,…

计算机视觉与模式识别 · 计算机科学 2025-08-28 Mingxi Fu , Fanglei Fu , Xitong Ling , Huaitian Yuan , Tian Guan , Yonghong He , Lianghui Zhu

Computational analysis of whole slide images (WSIs) has seen significant research progress in recent years, with applications ranging across important diagnostic and prognostic tasks such as survival or cancer subtype prediction. Many…

计算机视觉与模式识别 · 计算机科学 2024-11-28 Zak Buzzard , Konstantin Hemker , Nikola Simidjievski , Mateja Jamnik

Whole slide imaging (WSI) has transformed digital pathology by enabling computational analysis of gigapixel histopathology images. Recent foundation model advances have accelerated progress in computational pathology, facilitating joint…

计算机视觉与模式识别 · 计算机科学 2026-03-20 Peihang Wu , Zehong Chen , Lijian Xu

Spatial transcriptomics (ST) has emerged as a powerful technology for bridging histology imaging with gene expression profiling. However, its application has been limited by low throughput and the need for specialized experimental…

计算机视觉与模式识别 · 计算机科学 2025-06-09 Tinglin Huang , Tianyu Liu , Mehrtash Babadi , Wengong Jin , Rex Ying

The semantic segmentation task in pathology plays an indispensable role in assisting physicians in determining the condition of tissue lesions. With the proposal of Segment Anything Model (SAM), more and more foundation models have seen…

图像与视频处理 · 电气工程与系统科学 2024-09-05 Mingya Zhang , Liang Wang , Zhihao Chen , Yiyuan Ge , Xianping Tao

While spatial transcriptomics (ST) has advanced our understanding of gene expression in tissue context, its high experimental cost limits its large-scale application. Predicting ST from pathology images is a promising, cost-effective…

计算机视觉与模式识别 · 计算机科学 2026-03-25 Zhiceng Shi , Changmiao Wang , Jun Wan , Wenwen Min

Representation learning of pathology whole-slide images (WSIs) has primarily relied on weak supervision with Multiple Instance Learning (MIL). This approach leads to slide representations highly tailored to a specific clinical task.…

计算机视觉与模式识别 · 计算机科学 2025-03-25 Tim Lenz , Peter Neidlinger , Marta Ligero , Georg Wölflein , Marko van Treeck , Jakob Nikolas Kather

Visual Foundation Models (VFMs), such as DINO and CLIP, excel in semantic understanding of images but exhibit limited spatial reasoning capabilities, which limits their applicability to embodied systems. As a result, recent work…

计算机视觉与模式识别 · 计算机科学 2026-01-21 Turhan Can Kargin , Wojciech Jasiński , Adam Pardyl , Bartosz Zieliński , Marcin Przewięźlikowski

Whole Slide Images (WSIs) exhibit hierarchical structure, where diagnostic information emerges from cellular morphology, regional tissue organization, and global context. Existing Computational Pathology (CPath) Multimodal Large Language…

Computational pathology holds substantial promise for improving diagnosis and guiding treatment decisions. Recent pathology foundation models enable the extraction of rich patch-level representations from large-scale whole-slide images…

计算机视觉与模式识别 · 计算机科学 2025-11-20 Xiangde Luo , Jinxi Xiang , Yuanfeng Ji , Ruijiang Li

Weakly supervised whole slide image classification is a key task in computational pathology, which involves predicting a slide-level label from a set of image patches constituting the slide. Constructing models to solve this task involves…

Histopathological image analysis is an essential process for the discovery of diseases such as cancer. However, it is challenging to train CNN on whole slide images (WSIs) of gigapixel resolution considering the available memory capacity.…

图像与视频处理 · 电气工程与系统科学 2019-10-11 Shusuke Takahama , Yusuke Kurose , Yusuke Mukuta , Hiroyuki Abe , Masashi Fukayama , Akihiko Yoshizawa , Masanobu Kitagawa , Tatsuya Harada

Whole Slide Image (WSI) analysis plays a crucial role in modern digital pathology, enabling large-scale feature extraction from tissue samples. However, traditional feature extraction pipelines based on tools like CellProfiler often involve…

图像与视频处理 · 电气工程与系统科学 2025-01-13 Yuechen Yang , Yu Wang , Tianyuan Yao , Ruining Deng , Mengmeng Yin , Shilin Zhao , Haichun Yang , Yuankai Huo

The recent rapid development of Large Vision-Language Models (LVLMs) has indicated their potential for embodied tasks.However, the critical skill of spatial understanding in embodied environments has not been thoroughly evaluated, leaving…

人工智能 · 计算机科学 2024-06-11 Mengfei Du , Binhao Wu , Zejun Li , Xuanjing Huang , Zhongyu Wei