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Mid-infrared photo-induced force microscopy (IR-PiFM/PiF-IR) enables high-resolution chemical imaging of surfaces with lateral resolution less than 5 nm. Here are some answers to questions about the physical background, practical handling…

材料科学 · 物理学 2026-05-05 Daniela Täuber

Spectroscopy and imaging in the mid-infrared (2.5 $\mu$m $\sim$ $\lambda$ $\sim$ 25 $\mu$m) is bedevilled by the presence of a strong 300 K thermal background at room temperature that makes IR detectors decades noisier than can be readily…

量子物理 · 物理学 2023-11-28 Yue Ma , Nathan Gemmell , Emma Pearce , Rupert Oulton , Chris Phillips

Mid-infrared spectroscopy probes molecular vibrations to identify chemical species and functional groups. Therefore, mid-infrared hyperspectral imaging is one of the most powerful and promising candidates for chemical imaging using optical…

光学 · 物理学 2023-07-06 Yue Zhao , Shota Kusama , Yuji Furutani , Wei-Hong Huang , Chih-Wei Luo , Takao Fuji

Expanding far beyond traditional applications in optical interconnects at telecommunications wavelengths, the silicon nanophotonic integrated circuit platform has recently proven its merits for working with mid-infrared (mid-IR) optical…

Photothermal microscopy is an emerging tool for measuring light-matter interactions with single-molecule sensitivity. It is generally believed that the spectral acquisition speed in photothermal microscopy is limited by the slow thermal…

Mid-infrared photothermal microscopy is a new chemical imaging technology in which a visible beam senses the photothermal effect induced by a pulsed infrared laser. This technology provides infrared spectroscopic information at sub-micron…

光学 · 物理学 2021-04-08 Yi Zhang , Haonan Zong , Cheng Zong , Yuying Tan , Meng Zhang , Yuewei Zhan , Ji-Xin Cheng

Upconversion imaging, where mid infrared (IR) photons are converted to visible and near IR photons via a nonlinear crystal and detected on cheap and high-performance Silicon detectors, is an appealing method to address the limitations of…

光学 · 物理学 2020-02-05 Michael Mrejen , Yoni Erlich , Assaf Levanon , Haim Suchowski

For trace gas sensing and precision spectroscopy, optical cavities incorporating low-loss mirrors are indispensable for path length and optical intensity enhancement. Optical interference coatings in the visible and near-infrared (NIR)…

Recent developments in surface-enhanced Raman scattering (SERS) enable observation of single-bond vibrations in real-time at room temperature. By contrast, mid-infrared (MIR) vibrational spectroscopy is limited to inefficient slow…

Silicon's bandgap inherently restricts its photodetection to wavelengths below 1100 nm, necessitating the integration of costly III-V semiconductors for short-wave infrared applications. Hyperdoping silicon beyond the solid solubility limit…

Measuring subdiffraction separations between single fluorescent particles is important for biological, nano-, and medical-technology studies. Major challenges include (i) measuring changing molecular separations with high temporal…

生物物理 · 物理学 2015-05-18 Shawn H. DeCenzo , Michael C. DeSantis , Y. M. Wang

Single-photon avalanche diode (SPAD) arrays have transformed optical imaging by enabling photon-counting sensitivity, picosecond resolution, and high frame-rate operation. These capabilities, however, have remained confined to the visible…

We propose an on-chip mid-infrared (MIR) photonic spectroscopy platform for aerosol characterization to obtain highly discriminatory information on the chemistry of aerosol particles. Sensing of aerosols is crucial for various…

应用物理 · 物理学 2020-05-12 Robin Singh , Peter Su , Lionel Kimerling , Anu Agarwal , Brian W Anthony

Photothermal-Induced Resonance (PTIR) spectroscopy and imaging with infrared light has seen increasing application in molecular spectroscopy of biological samples. The appeal of the technique lies in its capability to provide information…

定量方法 · 定量生物学 2019-11-19 Luca Quaroni

Mid-infrared (MIR) emitters are critical components in advanced photonic systems, driving progress in fields such as chemical sensing, environmental monitoring, medical diagnostics, thermal imaging and free-space communications.…

介观与纳米尺度物理 · 物理学 2026-04-01 Shiyu Wang , Delang Liang , Zhi Zheng , Mingyang Qin , Yuchun Chen , Jie Sheng , Shula Chen , Lin Li , Changgan Zeng , Anlian Pan , Jinluo Cheng , Dong Sun

Imaging in thick biological tissues is often degraded by sample-induced aberrations, which reduce image quality and resolution, particularly in super-resolution techniques. While hardware-based adaptive optics, which correct aberrations…

Mid-infrared hyperspectral imaging has become an indispensable tool to spatially resolve chemical information in a wide variety of samples. However, acquiring three-dimensional data cubes is typically time-consuming due to the limited speed…

光学 · 物理学 2026-05-29 Jianan Fang , Kun Huang , Ruiyang Qin , Yan Liang , E Wu , Ming Yan , Heping Zeng

Mid-infrared absorption spectroscopy is a well-established technique for non-destructive quantitative molecular analysis. Waveguide-integrated sensors provide a particularly compact solution operating with reduced sample volumes while…

光学 · 物理学 2024-08-16 Antonia Torres-Cubillo , Andrea Teuber , Robert Halir , Boris Mizaikoff

The mid-infrared spectral range holds great promise for applications such as molecular spectroscopy and telecommunications. Many key molecules exhibit strong absorption features in this range, and free-space optical communication benefits…

Mid-infrared spectroscopy offers powerful label-free molecular analysis capabilities but faces significant challenges when analyzing complex biological samples. Here, we present a transformative surface-enhanced infrared absorption…