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Wounds in the embryo show a remarkable ability to heal quickly without leaving a scar. Previous studies have found that an actomyosin ring ("purse string") forms around the wound perimeter and contracts to close the wound over the course of…

组织与器官 · 定量生物学 2015-06-15 Matthew A. Wyczalkowski , Victor D. Varner , Larry A. Taber

Wounds in epithelial tissues compromise their vital role in homeostasis. A rapid and efficient wound healing encompasses different mechanisms, which includes the formation of a contractile actin-myosin cable around its edge, known as the…

软凝聚态物质 · 物理学 2024-03-22 R. F. Almada , N. A. M. Araujo , P. Patricio

We develop a model to investigate analytically and numerically the mechanics of wound opening made in a viscoelastic, isotropic, homogeneous, and incompressive thin tissue. This process occurs just immediately after the wound infliction.…

软凝聚态物质 · 物理学 2021-07-14 G. M. Carvalho , N. A. M. Araújo , P. Patrício

Jellyfish cyborgs present a promising avenue for soft robotic systems, leveraging the natural energy-efficiency and adaptability of biological systems. Here we demonstrate a novel approach to predicting and controlling jellyfish locomotion…

机器人学 · 计算机科学 2024-10-28 Dai Owaki , Max Austin , Shuhei Ikeda , Kazuya Okuizumi , Kohei Nakajima

We propose a model for the structure formation of jellyfish swimming based on active Brownian particles. We address the phenomena of counter-current swimming, avoidance of turbulent flow regions and foraging. We motivate corresponding…

适应与自组织系统 · 物理学 2023-04-21 Erik Gengel , Zafrir Kuplik , Dror Angel , Eyal Heifetz

We present a theory of jellyfish swarm formation and exemplify it with simulations of active Brownian particles. The motivation for our analysis is the phenomenon of jellyfish blooms in the ocean and clustering of jellyfish in tank…

适应与自组织系统 · 物理学 2024-11-26 Erik Gengel , Zafrir Kuplik , Dror Angel , Eyal Heifetz

Skin is the largest organ of many animals. Its protective function against hostile environments and predatorial attack makes high mechanical strength a vital characteristic. Here, we measured the mechanical properties of bass fish skins and…

生物物理 · 物理学 2023-02-01 Emily Zhang , Chi-Huan Tung , Luyi Feng , Yu Ren Zhou

We study theoretically the closure of a wound in a layer of epithelial cells in a living tissue after damage. Our analysis is informed by our recent experiments observing re-epithelialisation in vivo of Drosophila pupae. On time and…

A buckled sheet offers a reservoir of material that can be unfurled at a later time. For sufficiently thin yet stiff materials, this geometric process has a striking mechanical feature: when the slack runs out, the material locks to further…

软凝聚态物质 · 物理学 2025-11-18 Pan Dong , Mengfei He , Nathan C. Keim , Joseph D. Paulsen

We use experiments to study the dynamics of the healing of a blister, a localized bump in a thin elastic layer that is adhered to a soft substrate everywhere except at the bump. We create a blister by gently placing a glass cover slip on a…

软凝聚态物质 · 物理学 2014-02-04 Jonathan E. Longley , L. Mahadevan , Manoj K. Chaudhury

Herein, self-healing small-scale swimmers capable of autonomous propulsion and on-the-fly structural recovery are described. The new strategy instantaneously restores the functionality of the swimmer after it has suffered severe damage.…

Epithelization, the process whereby an epithelium covers a cell-free surface, is not only central to wound healing but also pivotal in embryonic morphogenesis, regeneration, and cancer. In the context of wound healing, the epithelization…

细胞行为 · 定量生物学 2014-02-21 Olivier Cochet-Escartin , Jonas Ranft , Pascal Silberzan , Philippe Marcq

Effective wound repair treatments rely on a clear picture of how cell proliferation and migration are coordinated during tissue restoration. Fibroblasts are key contributors to tissue restoration in the dermis, and modern imaging tools…

细胞行为 · 定量生物学 2026-03-03 Erik Blom , Qiyao Peng , Leah Pomfret , Richard Mort , Stefan Engblom

Wounding is a severe impairment of function, especially for an exposed organism like the network-forming true slime mould Physarum polycephalum. The tubular network making up the organism's body plan is entirely interconnected and shares a…

定量方法 · 定量生物学 2017-10-25 Felix Bäuerle , Mirna Kramar , Karen Alim

The paper studies a curvature flow linked to the physical phenomenon of wound closure. Under the flow we show that a closed, initially convex or close-to-convex curve shrinks to a round point in finite time. We also study the singularity,…

微分几何 · 数学 2018-02-13 Shuhui He , Glen Wheeler , Valentina-Mira Wheeler

The A901/2 system is a rare case of galaxy cluster interaction, in which two galaxy clusters and two smaller groups are seen in route of collision with each other simultaneously. Within each of the four substructures, several galaxies with…

Tissue fusion eliminates physical voids in a tissue to form a continuous structure and is central to many processes in development and repair. Fusion events in vivo, particularly in embryonic development, often involve the purse-string…

组织与器官 · 定量生物学 2015-08-12 V. Nier , M. Deforet , G. Duclos , H. G. Yevick , O. Cochet-Escartin , P. Marcq , P. Silberzan

When they are damaged or injured, soft biological tissues are able to self-repair and heal. Mechanics is critical during the healing process, as the damaged extracellular matrix (ECM) tends to be replaced with a new undamaged ECM supporting…

计算工程、金融与科学 · 计算机科学 2021-12-08 Di Zuo , Yiqian He , Stéphane Avril , Haitian Yang , Klaus Hackl

It is well known that galaxies falling into clusters can experience gas stripping due to ram-pressure by the intra-cluster medium (ICM). The most spectacular examples are galaxies with extended tails of optically-bright stripped material…

Microgels are soft colloids that, in virtue of their polymeric nature, can react to external stimuli such as temperature or pH by changing their size. The resulting swelling/deswelling transition can be exploited in fundamental research as…

软凝聚态物质 · 物理学 2019-02-15 Lorenzo Rovigatti , Nicoletta Gnan , Emanuela Zaccarelli
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