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Modern wearable devices are embedded with a range of noninvasive biomarker sensors that hold promise for improving detection and treatment of disease. One such sensor is the single-lead electrocardiogram (ECG) which measures electrical…

机器学习 · 统计学 2020-12-02 Jeffrey Chan , Andrew C. Miller , Emily B. Fox

Photoplethysmography is a non-invasive optical technique that measures changes in blood volume within tissues. It is commonly and increasingly used for in a variety of research and clinical application to assess vascular dynamics and…

医学物理 · 物理学 2023-09-26 Marton A. Goda , Peter H. Charlton , Joachim A. Behar

Smart watches and other wearable devices are equipped with photoplethysmography (PPG) sensors for monitoring heart rate and other aspects of cardiovascular health. However, PPG signals collected from such devices are susceptible to…

信号处理 · 电气工程与系统科学 2023-07-12 Pranay Jain , Cheng Ding , Cynthia Rudin , Xiao Hu

Process capability index (PCI) is a commonly used statistic to measure ability of a process to operate within the given specifications or to produce products which meet the required quality specifications. PCI can be univariate or…

应用统计 · 统计学 2018-11-19 Deovrat Kakde , Arin Chaudhuri , Diana Shaw

Modern wearable devices can conveniently record various biosignals in the many different environments of daily living, enabling a rich view of individual health. However, not all biosignals are the same: high-fidelity biosignals, such as…

机器学习 · 计算机科学 2025-02-03 Salar Abbaspourazad , Anshuman Mishra , Joseph Futoma , Andrew C. Miller , Ian Shapiro

Automated cardiac image interpretation has the potential to transform clinical practice in multiple ways including enabling low-cost serial assessment of cardiac function in the primary care and rural setting. We hypothesized that advances…

Photoplethysmogram (PPG) signal-based blood pressure (BP) estimation is a promising candidate for modern BP measurements, as PPG signals can be easily obtained from wearable devices in a non-invasive manner, allowing quick BP measurement.…

信号处理 · 电气工程与系统科学 2021-03-01 Hyeongju Kim , Woo Hyun Kang , Hyeonseung Lee , Nam Soo Kim

This work aims at identifying and quantifying uncertainties related to elastic and viscoelastic parameters, which characterize the arterial wall behavior, in one-dimensional modeling of the human arterial hemodynamics. The chosen uncertain…

流体动力学 · 物理学 2021-02-12 Giulia Bertaglia , Valerio Caleffi , Lorenzo Pareschi , Alessandro Valiani

A challenging problem in estimating high-dimensional graphical models is to choose the regularization parameter in a data-dependent way. The standard techniques include $K$-fold cross-validation ($K$-CV), Akaike information criterion (AIC),…

机器学习 · 统计学 2010-06-18 Han Liu , Kathryn Roeder , Larry Wasserman

Low physical activity levels in the intensive care units (ICU) patients have been linked to adverse clinical outcomes. Therefore, there is a need for continuous and objective measurement of physical activity in the ICU to quantify the…

人机交互 · 计算机科学 2021-10-08 Anis Davoudi , Patrick J. Tighe , Azra Bihorac , Parisa Rashidi

Pulmonary embolisms (PE) are known to be one of the leading causes for cardiac-related mortality. Due to inherent variabilities in how PE manifests and the cumbersome nature of manual diagnosis, there is growing interest in leveraging AI…

图像与视频处理 · 电气工程与系统科学 2019-10-23 Deepta Rajan , David Beymer , Shafiqul Abedin , Ehsan Dehghan

We introduce a high-throughput platform that enables simultaneous, parallel testing of six bistable beams via programmable motion of a rotating disk. By prescribing harmonic angular dynamics, the platform explores the phase space of angular…

软凝聚态物质 · 物理学 2025-12-11 Eduardo Gutierrez-Prieto , Gilad Yakir , Pedro M. Reis

Mathematical models are essential tools to study how the cardiovascular system maintains homeostasis. The utility of such models is limited by the accuracy of their predictions, which can be determined by uncertainty quantification (UQ). A…

定量方法 · 定量生物学 2018-07-20 Andrew D. Marquis , Andrea Arnold , Caron Dean , Brian E. Carlson , Mette S. Olufsen

More than 10 million coronary angiograms are performed globally each year, providing a gold standard for detecting obstructive coronary artery disease. Yet, no obstructive lesions are identified in 70% of patients evaluated for ischemic…

This work proposes Attractor-Vascular Coupling Theory (AVCT), a mathematical framework showing that cardiac attractor geometry encodes blood pressure (BP) information sufficient for AAMI-standard estimation, and validates the theory through…

医学物理 · 物理学 2026-05-19 Timothy Oladunni , Farouk Ganiyu Adewumi

Diabetes mellitus affects over 537 million adults worldwide. Insulin-dependent patients require continuous glucose monitoring and precise dose calculation while operating under strict power budgets on wearable devices. This paper presents…

机器学习 · 计算机科学 2026-03-31 Sahil Shrivastava

Machine learning methods provide a methodological innovation that can help screen for cardiovascular disease through noninvasive and readily available measurement modalities. Recent investments in using electrocardiogram (ECG) data to…

定量方法 · 定量生物学 2026-05-25 Mitchel J. Colebank

Ankle sprains and instability are major public health concerns. Up to 70% of individuals do not fully recover from a single ankle sprain and eventually develop chronic ankle instability (CAI). The diagnosis of CAI has been mainly based on…

机器学习 · 计算机科学 2019-11-20 Shaodi Qian , Sheng-Che Yen , Eric Folmar , Chun-An Chou

We present GPU-SLS, a GPU-parallelized framework for safe, robust nonlinear model predictive control (MPC) that scales to high-dimensional uncertain robotic systems and long planning horizons. Our method jointly optimizes an…

机器人学 · 计算机科学 2026-04-10 Jeffrey Fang , Glen Chou

Smart wearables enable continuous tracking of established biomarkers such as heart rate, heart rate variability, and blood oxygen saturation via photoplethysmography (PPG). Beyond these metrics, PPG waveforms contain richer physiological…