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Continuous blood pressure (BP) estimation via photoplethysmography (PPG) remains a significant challenge, particularly in providing comprehensive cardiovascular insights for hypertensive complications. This study presents a novel…

医学物理 · 物理学 2025-04-24 Yaowen Zhang , Libera Fresiello , Peter H. Veltink , Dirk W. Donker , Ying Wang

Enhancing the precision of segmenting coronary atherosclerotic plaques from CT Angiography (CTA) images is pivotal for advanced Coronary Atherosclerosis Analysis (CAA), which distinctively relies on the analysis of vessel cross-section…

图像与视频处理 · 电气工程与系统科学 2025-01-15 Ziheng Zhang , Zihan Li , Dandan Shan , Yuehui Qiu , Qingqi Hong , Qingqiang Wu

Objective. Wearable devices with embedded photoplethysmography (PPG) enable continuous non-invasive monitoring of cardiac activity, offering a promising strategy to reduce the global burden of cardiovascular diseases. However, monitoring…

信号处理 · 电气工程与系统科学 2025-08-15 Giulio Basso , Xi Long , Reinder Haakma , Rik Vullings

Wearable systems provide continuous health monitoring and can lead to early detection of potential health issues. However, the lifecycle of wearable systems faces several challenges. First, effective model training for new wearable devices…

Photoplethysmography (PPG)-based blood pressure (BP) estimation is a challenging task, particularly on resource-constrained wearable devices. However, fully on-board processing is desirable to ensure user data confidentiality. Recent deep…

Patient-specific modeling of cardiovascular flows with high-fidelity is challenging due to its dependence on accurately estimated velocity boundary profiles, which are essential for precise simulations and directly influence wall shear…

Sudden cardiac death and arrhythmia account for a large percentage of all deaths worldwide. Electrocardiography (ECG) is the most widely used screening tool for cardiovascular diseases. Traditionally, ECG signals are classified manually,…

信号处理 · 电气工程与系统科学 2022-06-16 Li Xiaolin , Fang Xiang , Rajesh C. Panicker , Barry Cardiff , Deepu John

This paper proposes a statistical verification framework using Gaussian processes (GPs) for simulation-based verification of stochastic nonlinear systems with parametric uncertainties. Given a small number of stochastic simulations, the…

系统与控制 · 计算机科学 2017-10-03 John F. Quindlen , Ufuk Topcu , Girish Chowdhary , Jonathan P. How

The oscillations of the human heart rate are inherently complex and non-linear -- they are best described by mathematical chaos, and they present a challenge when applied to the practical domain of cardiovascular health monitoring in…

机器学习 · 计算机科学 2025-11-03 Berken Utku Demirel , Christian Holz

Computational hemodynamics models are becoming increasingly useful in the management and prognosis of complex, multiscale pathologies, including those attributed to the development of pulmonary vascular disease. However, diseases like…

组织与器官 · 定量生物学 2025-06-06 Mitchel J. Colebank , Naomi C. Chesler

Pulmonary hypertension (PH), defined by a mean pulmonary arterial pressure (mPAP) $>$ 20 mmHg, is characterized by increased pulmonary vascular resistance and decreased pulmonary arterial compliance. There are few measurable biomarkers of…

定量方法 · 定量生物学 2025-06-06 Amanda L. Colunga , Mitchel J. Colebank , REU Program , Mette S. Olufsen

Wearable electrocardiograph (ECG) recording and processing systems have been developed to detect cardiac arrhythmia to help prevent heart attacks. Conventional wearable systems, however, suffer from high energy consumption at both circuit…

信号处理 · 电气工程与系统科学 2022-05-27 Jinbo Chen , Fengshi Tian , Jie Yang , Mohamad Sawan

Hyperkalemia is a life-threatening electrolyte disorder that is common in patients with chronic kidney disease and heart failure, yet frequent monitoring remains difficult outside hospital settings. We developed and validated Pocket-K, a…

The presented study aims to estimate blood pressure (BP) using photoplethysmogram (PPG) signals while employing multiple machine learning models. The study proposes a novel algorithm for signal reconstruction, which utilizes the…

信号处理 · 电气工程与系统科学 2023-01-23 Aayushman Ghosh , Sayan Sarkar , Jayant Kalra

Physical models of biological systems can become difficult to interpret when they have a large number of parameters. But the models themselves actually depend on (i.e. are sensitive to) only a subset of those parameters. Rigorously…

生物物理 · 物理学 2018-11-27 Chieh-Ting Hsu , Gary J. Brouhard , Paul François

The artificial intelligence (AI) system has achieved expert-level performance in electrocardiogram (ECG) signal analysis. However, in underdeveloped countries or regions where the healthcare information system is imperfect, only paper ECGs…

Most deep learning models of multiclass arrhythmia classification are tested on fingertip photoplethysmographic (PPG) data, which has higher signal-to-noise ratios compared to smartwatch-derived PPG, and the best reported sensitivity value…

Sensitivity to staining variation remains a major barrier to deploying computational pathology (CPath) models as hematoxylin and eosin (H&E) staining varies across laboratories, requiring systematic assessment of how this variability…

This paper concerns the adaptive control problem for a class of nonlinear stochastic systems in which the state update is given by a nonlinear function of linear dynamics plus additive stochastic noise. Such systems arise in a wide range of…

系统与控制 · 电气工程与系统科学 2026-04-09 Lantian Zhang , Bo Wahlberg , Silun Zhang

Photoplethysmography (PPG) is widely used as a non-invasive and accessible modality for continuous health monitoring. However, despite being a peripheral hemodynamic signal intrinsically coupled with systemic circulation, existing research…

信号处理 · 电气工程与系统科学 2026-03-20 Guangkun Nie , Xiaocheng Fang , Gongzheng Tang , Yujie Xiao , Jun Li , Bo Liu , Hongyan Li , Shenda Hong