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Computer-driven molecular design combines the principles of chemistry, physics, and artificial intelligence to identify novel chemical compounds and materials with desired properties for a specific application. In particular,…

化学物理 · 物理学 2023-09-04 Alessio Fallani , Leonardo Medrano Sandonas , Alexandre Tkatchenko

Predicting and enhancing inherent properties based on molecular structures is paramount to design tasks in medicine, materials science, and environmental management. Most of the current machine learning and deep learning approaches have…

机器学习 · 计算机科学 2024-04-08 Zachary R. Fox , Ayana Ghosh

Ultra-high dimensional longitudinal data are increasingly common and the analysis is challenging both theoretically and methodologically. We offer a new automatic procedure for finding a sparse semivarying coefficient model, which is widely…

统计方法学 · 统计学 2014-09-24 Ming-Yen Cheng , Toshio Honda , Jialiang Li , Heng Peng

In many environmental applications involving spatially-referenced data, limitations on the number and locations of observations motivate the need for practical and efficient models for spatial interpolation, or kriging. A key component of…

统计方法学 · 统计学 2015-09-15 Mark D. Risser , Catherine A. Calder

With a goal of accelerating fabrication of additively manufactured components with precise microstructures, we developed a method for structural characterization of key features in additively manufactured materials and parts. The method…

计算机视觉与模式识别 · 计算机科学 2023-02-14 Amra Peles , Vincent C. Paquit , Ryan R. Dehoff

Spatial variables can be observed in many different forms, such as regularly sampled random fields (lattice data), point processes, and randomly sampled spatial processes. Joint analysis of such collections of observations is clearly…

统计方法学 · 统计学 2026-05-20 Jake P. Grainger , Tuomas A. Rajala , David J. Murrell , Sofia C. Olhede

Current sparse autoencoder (SAE) approaches to neural network interpretability assume that activations can be decomposed through linear superposition into sparse, interpretable features. Despite high reconstruction fidelity, SAEs…

神经元与认知 · 定量生物学 2025-12-10 Omar Claflin

Materials exhibit geometric structures across mesoscopic to microscopic scales, influencing macroscale properties such as appearance, mechanical strength, and thermal behavior. Capturing and modeling these multiscale structures is…

图形学 · 计算机科学 2025-04-15 Bojja Venu , Adam Bosak , Juan Raul Padron-Griffe

Dealing with land cover classification of the new image sources has also turned to be a complex problem requiring large amount of memory and processing time. In order to cope with these problems, statistical learning has greatly helped in…

We propose an off-line approach to explicitly encode temporal patterns spatially as different types of images, namely, Gramian Angular Fields and Markov Transition Fields. This enables the use of techniques from computer vision for feature…

机器学习 · 计算机科学 2015-09-25 Zhiguang Wang , Tim Oates

Every molecule ever synthesised can be drawn as a 2D skeletal diagram, yet in modern property prediction this universally available representation has received less focus in favour of molecular graphs, 3D conformers, or billion-parameter…

计算机视觉与模式识别 · 计算机科学 2026-05-12 Aaditya Baranwal , Akshaj Gupta , Shruti Vyas , Yogesh S Rawat

Statistical quality control in semiconductor manufacturing hinges on effective diagnostics of wafer bin maps, wherein a key challenge is to detect how defective chips tend to spatially cluster on a wafer--a problem known as spatial pattern…

应用统计 · 统计学 2021-03-01 Ahmed Aziz Ezzat , Sheng Liu , Dorit S. Hochbaum , Yu Ding

Virtual screening can accelerate drug discovery by identifying promising candidates for experimental evaluation. Machine learning is a powerful method for screening, as it can learn complex structure-property relationships from experimental…

机器学习 · 计算机科学 2021-02-22 Simon Axelrod , Rafael Gomez-Bombarelli

Significant advances in biotechnology have allowed for simultaneous measurement of molecular data points across multiple genomic and transcriptomic levels from a single tumor/cancer sample. This has motivated systematic approaches to…

Discovery of the molecular candidates for applications in drug targets, biomolecular systems, catalysts, photovoltaics, organic electronics, and batteries, necessitates development of machine learning algorithms capable of rapid exploration…

机器学习 · 计算机科学 2023-12-12 Ayana Ghosh , Sergei V. Kalinin , Maxim A. Ziatdinov

One of the most powerful techniques to study protein structures is to look for recurrent fragments (also called substructures or spatial motifs), then use them as patterns to characterize the proteins under study. An emergent trend consists…

计算工程、金融与科学 · 计算机科学 2018-03-02 Wajdi Dhifli , Rabie Saidi , Engelbert Mephu Nguifo

Structural transformation, the shift from agrarian economies to more diversified industrial and service-based systems, is a key driver of economic development. However, in low- and middle-income countries (LMICs), data scarcity and…

应用统计 · 统计学 2025-10-02 Ronald Katende

One of the main computational bottlenecks when working with kernel based learning is dealing with the large and typically dense kernel matrix. Techniques dealing with fast approximations of the matrix vector product for these kernel…

机器学习 · 计算机科学 2024-04-29 Theresa Wagner , Franziska Nestler , Martin Stoll

Many real-world physics and engineering problems arise in geometrically complex domains discretized by meshes for numerical simulations. The nodes of these potentially irregular meshes naturally form point clouds whose limited tractability…

机器学习 · 计算机科学 2025-06-17 Shirin Hosseinmardi , Ramin Bostanabad

Point defects in solid-state materials are now routinely simulated using large supercell structures, requiring efficient quantum mechanical solutions. Data-driven and machine learning (ML) models trained on computational data can enable…

材料科学 · 物理学 2026-05-26 Arun Mannodi-Kanakkithodi , Menglin Huang , Prashun Gorai , Seán R. Kavanagh