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Biomedical knowledge graphs are increasingly large, dynamic, and multimodal, driven by rapid advances in biotechnology such as high-throughput sequencing. Machine learning models can infer previously unobserved biomedical relationships and…

机器学习 · 计算机科学 2026-05-12 Yousef A. Radwan , Yao Li , Qing Qing , Ziqi Xu , Qixin Zhang , Yongcheng Jing , Renqiang Luo , Xikun Zhang

The advent of large language models (LLMs) has revolutionized the integration of knowledge graphs (KGs) in biomedical and cognitive sciences, overcoming limitations in traditional machine learning methods for capturing intricate semantic…

人工智能 · 计算机科学 2025-10-09 Ali Sarabadani , Kheirolah Rahsepar Fard

Biomedical Knowledge Graphs (BKGs) integrate diverse datasets to elucidate complex relationships within the biomedical field. Effective link prediction on these graphs can uncover valuable connections, such as potential novel drug-disease…

计算与语言 · 计算机科学 2025-07-01 Tien Dang , Viet Thanh Duy Nguyen , Minh Tuan Le , Truong-Son Hy

Biomedical knowledge graphs (KGs) treat disease associations as static facts, but temporal information is crucial for clinical reasoning, e.g., a symptom diagnostic of one disease at age 3 may imply a different disease at age 13. Existing…

计算与语言 · 计算机科学 2026-05-22 Md Shamim Ahmed , Farzaneh Firoozbakht , Lukas Galke Poech , Jan Baumbach , Richard Röttger

Biomedical knowledge graphs (KGs) are widely used in the life sciences, yet many are derived from unstructured documents and therefore lack schema-level constrains, whereas graphs assembled from structured resources are difficult to…

Large language models (LLMs) are increasingly used in the mental health domain, yet it remains unclear how well they capture related biomedical knowledge and how reliably they apply it to clinically salient structured judgments. Here, we…

Biomedical knowledge graphs (KGs) are widely used across research and translational settings, yet their design decisions and implementation are often opaque. Unlike ontologies that more frequently adhere to established creation principles,…

Currently, there is a rapidly increasing need for high-quality biomedical knowledge graphs (BioKG) that provide direct and precise biomedical knowledge. In the context of COVID-19, this issue is even more necessary to be highlighted.…

人工智能 · 计算机科学 2020-12-03 Sendong Zhao , Bing Qin , Ting Liu , Fei Wang

The rapid expansion of medical literature presents growing challenges for structuring and integrating domain knowledge at scale. Knowledge Graphs (KGs) offer a promising solution by enabling efficient retrieval, automated reasoning, and…

The purpose of this study is to introduce SKG-LLM. A knowledge graph (KG) is constructed from stroke-related articles using mathematical and large language models (LLMs). SKG-LLM extracts and organizes complex relationships from the…

人工智能 · 计算机科学 2025-03-11 Ali Sarabadani , Kheirolah Rahsepar Fard , Hamid Dalvand

Medical language models must be updated as evidence and terminology evolve, yet sequential updating can trigger catastrophic forgetting. Although biomedical NLP has many static benchmarks, no unified, task-diverse benchmark exists for…

人工智能 · 计算机科学 2026-03-18 Min Zeng , Shuang Zhou , Zaifu Zhan , Rui Zhang

Medical deep learning models depend heavily on domain-specific knowledge to perform well on knowledge-intensive clinical tasks. Prior work has primarily leveraged unimodal knowledge graphs, such as the Unified Medical Language System…

人工智能 · 计算机科学 2025-05-26 Xiaochen Wang , Yuan Zhong , Lingwei Zhang , Lisong Dai , Ting Wang , Fenglong Ma

The reliable evaluation of large language models (LLMs) in medical applications remains an open challenge, particularly in capturing the complexity of multi-turn doctor-patient interactions that unfold in real clinical environments.…

人工智能 · 计算机科学 2025-10-15 Yuechun Yu , Han Ying , Haoan Jin , Wenjian Jiang , Dong Xian , Binghao Wang , Zhou Yang , Mengyue Wu

Knowledge graphs are powerful tools for representing and organising complex biomedical data. Several knowledge graph embedding algorithms have been proposed to learn from and complete knowledge graphs. However, a recent study demonstrates…

Knowledge graphs have emerged as a key abstraction for organizing information in diverse domains and their embeddings are increasingly used to harness their information in various information retrieval and machine learning tasks. However,…

分布式、并行与集群计算 · 计算机科学 2020-04-21 Da Zheng , Xiang Song , Chao Ma , Zeyuan Tan , Zihao Ye , Jin Dong , Hao Xiong , Zheng Zhang , George Karypis

Large language models (LLMs) offer new opportunities for constructing knowledge graphs (KGs) from unstructured clinical narratives. However, existing approaches often rely on structured inputs and lack robust validation of factual accuracy…

人工智能 · 计算机科学 2026-01-06 Udiptaman Das , Krishnasai B. Atmakuri , Duy Ho , Chi Lee , Yugyung Lee

The embedding of Biomedical Knowledge Graphs (BKGs) generates robust representations, valuable for a variety of artificial intelligence applications, including predicting drug combinations and reasoning disease-drug relationships.…

数据库 · 计算机科学 2023-10-17 Zhiguang Fan , Yuedong Yang , Mingyuan Xu , Hongming Chen

Knowledge graphs (KGs) have emerged as a powerful framework for representing and integrating complex biomedical information. However, assembling KGs from diverse sources remains a significant challenge in several aspects, including entity…

机器学习 · 计算机科学 2023-10-10 Yijia Xiao , Dylan Steinecke , Alexander Russell Pelletier , Yushi Bai , Peipei Ping , Wei Wang

Continual graph learning (CGL) studies the problem of learning from an infinite stream of graph data, consolidating historical knowledge, and generalizing it to the future task. At once, only current graph data are available. Although some…

机器学习 · 计算机科学 2023-08-17 Qinghua Shen , Weijieying Ren , Wei Qin

Continual learning on graph data has recently attracted paramount attention for its aim to resolve the catastrophic forgetting problem on existing tasks while adapting the sequentially updated model to newly emerged graph tasks. While there…

机器学习 · 计算机科学 2024-02-20 Xikun Zhang , Dongjin Song , Dacheng Tao
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