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LLMs are increasingly deployed in autonomous laboratories, under the assumption that their domain priors and reasoning over iterative feedback let them converge on good designs in fewer iterations than feedback-only baselines. Current…

机器学习 · 计算机科学 2026-05-18 Marilyn Zhang , Tianfeng Chen , Fabián Barzuna , Ankita Rathod , Mark E. Whiting

Current Large Language Models (LLMs) exhibit significant limitations, notably in structured, interpretable, and verifiable medical reasoning, alongside practical deployment challenges related to computational resources and data privacy.…

We present a framework for training large language models (LLMs) as diagnostic agents with reinforcement learning, enabling them to manage multi-turn interactive diagnostic processes, adaptively select examinations, and commit to final…

PET theranostics is transforming precision oncology, yet treatment response varies substantially; many patients receiving 177Lu-PSMA radioligand therapy (RLT) for metastatic castration-resistant prostate cancer (mCRPC) fail to respond,…

Numerous methods have been proposed to measure LLM misgendering, including probability-based evaluations (e.g., automatically with templatic sentences) and generation-based evaluations (e.g., with automatic heuristics or human validation).…

计算与语言 · 计算机科学 2025-08-05 Arjun Subramonian , Vagrant Gautam , Preethi Seshadri , Dietrich Klakow , Kai-Wei Chang , Yizhou Sun

Multi-agent systems achieve state-of-the-art outcomes through peer collaboration. However, when an agent in the pipeline silently drops a constraint, the system's final output may look correct even though the reasoning chain was quietly…

Current Large Language Models (LLMs), especially Large Reasoning Models, can generate Chain-of-Thought (CoT) reasoning traces to illustrate how they produce final outputs, thereby facilitating trust calibration for users. However, these CoT…

人机交互 · 计算机科学 2026-04-07 Shiwei Chen , Niruthikka Sritharan , Xiaolin Wen , Chenxi Zhang , Xingbo Wang , Yong Wang

Large language models (LLMs) are being rapidly integrated into decision-support tools, automation workflows, and AI-enabled software systems. However, their behavior in production environments remains poorly understood, and their failure…

人工智能 · 计算机科学 2025-11-27 Vaishali Vinay

Large language models are increasingly being assembled into medical multi-agent systems that emulate multidisciplinary consultation through specialist roles, peer review and consensus formation. In clinical decision support, however,…

Most reported gains on agentic-LLM clinical benchmarks are often attributed to prompt engineering, yet our results suggest that larger improvements can come from architectural and engine-level design. We present MDIA, a Multi-agent…

人工智能 · 计算机科学 2026-05-26 Roberto Cruz , David Rey-Blanco

Continuing advances in Large Language Models (LLMs) in artificial intelligence offer important capacities in intuitively accessing and using medical knowledge in many contexts, including education and training as well as assessment and…

计算与语言 · 计算机科学 2024-08-01 Roma Shusterman , Allison C. Waters , Shannon O`Neill , Phan Luu , Don M. Tucker

Large Language Models are being increasingly deployed as the decision-making core of autonomous agents capable of effecting change in external environments. Yet, in conversational benchmarks, which simulate real-world customer-centric issue…

计算与语言 · 计算机科学 2026-04-29 Amir Saeidi , Venkatesh Mishra , Souradeep Mukhopadhyay , Gaowen Liu , Ali Payani , Jayanth Srinivasa , Chitta Baral

Large language models (LLMs) are increasingly evaluated in clinical settings using multi-dimensional rubrics which quantify reasoning quality, safety, and patient-centeredness. Yet, replicating specific mistakes in other LLM models is not…

计算与语言 · 计算机科学 2026-04-08 Oleksii Proniakin , Diego Fajardo , Ruslan Nazarenko , Razvan Marinescu

Vision-Language Models (VLMs) can generate convincing clinical narratives, yet frequently struggle to visually ground their statements. We posit this limitation arises from the scarcity of high-quality, large-scale clinical…

计算机视觉与模式识别 · 计算机科学 2026-01-13 Mengmeng Zhang , Xiaoping Wu , Hao Luo , Fan Wang , Yisheng Lv

Large Language Models (LLMs) have shown impressive performance on existing medical question-answering benchmarks. This high performance makes it increasingly difficult to meaningfully evaluate and differentiate advanced methods. We present…

Chain-of-Thought (CoT) reasoning has proven effective in enhancing large language models by encouraging step-by-step intermediate reasoning, and recent advances have extended this paradigm to Multimodal Large Language Models (MLLMs). In the…

图像与视频处理 · 电气工程与系统科学 2026-03-24 Juntao Jiang , Jiangning Zhang , Yali Bi , Jinsheng Bai , Weixuan Liu , Weiwei Jin , Zhucun Xue , Yong Liu , Xiaobin Hu , Shuicheng Yan

The rapid development of Large Language Models (LLMs) has transformed fake news detection and fact-checking tasks from simple classification to complex reasoning. However, evaluation frameworks have not kept pace. Current benchmarks are…

计算与语言 · 计算机科学 2026-04-21 Cheng Xu , Changhong Jin , Yingjie Niu , Nan Yan , Yuke Mei , Shuhao Guan , Liming Chen , M-Tahar Kechadi

The application of the Multi-modal Large Language Models (MLLMs) in medical clinical scenarios remains underexplored. Previous benchmarks only focus on the capacity of the MLLMs in medical visual question-answering (VQA) or report…

计算与语言 · 计算机科学 2024-08-19 Hongcheng Liu , Yusheng Liao , Siqv Ou , Yuhao Wang , Heyang Liu , Yanfeng Wang , Yu Wang

Large language model (LLM) agents perform strongly on short- and mid-horizon tasks, but often break down on long-horizon tasks that require extended, interdependent action sequences. Despite rapid progress in agentic systems, these…

Large Language Models (LLMs) and causal learning each hold strong potential for clinical decision making (CDM). However, their synergy remains poorly understood, largely due to the lack of systematic benchmarks evaluating their integration…

机器学习 · 计算机科学 2025-11-14 Linna Wang , Zhixuan You , Qihui Zhang , Jiunan Wen , Ji Shi , Yimin Chen , Yusen Wang , Fanqi Ding , Ziliang Feng , Li Lu