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Infectious disease outbreaks recapitulate biology: they emerge from the multi-level interaction of hosts, pathogens, and their shared environment. As a result, predicting when, where, and how far diseases will spread requires a complex…

物理与社会 · 物理学 2018-10-11 Samuel V. Scarpino , Giovanni Petri

In low-resource settings, prevalence mapping relies on empirical prevalence data from a finite, often spatially sparse, set of surveys of communities within the region of interest, possibly supplemented by remotely sensed images that can…

应用统计 · 统计学 2015-05-27 Peter J. Diggle , Emanuele Giorgi

During the ongoing COVID-19 pandemic, mathematical models of epidemic spreading have emerged as powerful tools to produce valuable predictions of the evolution of the pandemic, helping public health authorities decide which intervention…

动力系统 · 数学 2021-11-18 Lorenzo Zino , Ming Cao

The lack of standardization in seizure forecasting slows progress in the field and limits the clinical translation of forecasting models. In this work, we introduce a Python-based framework aimed at streamlining the development, assessment,…

As the global HIV pandemic enters its fourth decade, increasing numbers of surveillance sites have been established which allows countries to look into the epidemics at a finer scale, e.g. at sub-national level. However, the epidemic models…

应用统计 · 统计学 2014-11-18 Le Bao , Mary Mahy , Xiaoyue Niu , Tim Brown , Peter Ghys

Ending the HIV/AIDS pandemic is among the Sustainable Development Goals for the next decade. In order to overcome the gap between the need for care and the available resources, better understanding of HIV epidemics is needed to guide policy…

应用统计 · 统计学 2020-09-03 Zhou Lan , Le Bao

In the last fifty years, researchers have developed statistical, data-driven, analytical, and algorithmic approaches for designing and improving emergency response management (ERM) systems. The problem has been noted as inherently difficult…

Pandemic management requires that scientists rapidly formulate and analyze epidemiological models in order to forecast the spread of disease and the effects of mitigation strategies. Scientists must modify existing models and create novel…

编程语言 · 计算机科学 2022-10-12 Sophie Libkind , Andrew Baas , Micah Halter , Evan Patterson , James Fairbanks

WeatherBench is a benchmark dataset for medium-range weather forecasting of geopotential, temperature and precipitation, consisting of preprocessed data, predefined evaluation metrics and a number of baseline models. WeatherBench…

大气与海洋物理 · 物理学 2022-05-03 Sagar Garg , Stephan Rasp , Nils Thuerey

We investigate a model for spatial epidemics explicitly taking into account bi-directional movements between base and destination locations on individual mobility networks. We provide a systematic analysis of generic dynamical features of…

物理与社会 · 物理学 2012-03-07 Vitaly Belik , Theo Geisel , Dirk Brockmann

Tandem mass spectrometry provides a high-throughput framework for identifying and quantifying proteins in complex biological samples. In computational proteomics, predicting peptide MS/MS spectra is a critical task, enabling downstream…

机器学习 · 计算机科学 2026-05-05 Zhiwen Yang , Pan Liu , Yifan Li , Yunhua Zhong , Jun Xia

A typical problem in air pollution epidemiology is exposure assessment for individuals for which health data are available. Due to the sparsity of monitoring sites and the limited temporal frequency with which measurements of air pollutants…

Extreme precipitation events, such as violent rainfall and hail storms, routinely ravage economies and livelihoods around the developing world. Climate change further aggravates this issue. Data-driven deep learning approaches could widen…

In small area estimation, it is sometimes necessary to use model-based methods to produce estimates in areas with little or no data. In official statistics, we often require that some aggregate of small area estimates agree with a national…

统计方法学 · 统计学 2023-01-31 Taylor Okonek , Jon Wakefield

The basic and effective reproduction numbers are widely used metrics for characterizing the dynamics of infectious disease epidemics. However, the interpretation of these numbers is based on the assumption of homogeneous mixing and may not…

种群与进化 · 定量生物学 2026-03-24 Zahra Ghadiri , Jari Saramäki , Takayuki Hiraoka

Spatial epidemiology identifies the drivers of elevated population-level disease risks, using disease counts, exposures and known confounders at the areal unit level. Poisson regression models are typically used for inference, which…

统计方法学 · 统计学 2026-02-03 Duncan Lee , Vinny Davies

Spatial confounding poses a significant challenge in scientific studies involving spatial data, where unobserved spatial variables can influence both treatment and outcome, possibly leading to spurious associations. To address this problem,…

Scientific research follows multi-turn, multi-step workflows that require proactively searching the literature, consulting figures and tables, and integrating evidence across papers to align experimental settings and support reproducible…

计算与语言 · 计算机科学 2026-04-08 Xuan Dong , Huanyang Zheng , Tianhao Niu , Zhe Han , Pengzhan Li , Bofei Liu , Zhengyang Liu , Guancheng Li , Qingfu Zhu , Wanxiang Che

Bayesian inference methods are useful in infectious diseases modeling due to their capability to propagate uncertainty, manage sparse data, incorporate latent structures, and address high-dimensional parameter spaces. However, parameter…

统计方法学 · 统计学 2025-04-29 Xiahui Li , Fergus Chadwick , Ben Swallow

The scientific rigor and computational methods of causal inference have had great impacts on many disciplines, but have only recently begun to take hold in spatial applications. Spatial casual inference poses analytic challenges due to…

统计方法学 · 统计学 2020-07-07 Brian J Reich , Shu Yang , Yawen Guan , Andrew B Giffin , Matthew J Miller , Ana G Rappold