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The integration of Large Language Models (LLMs) into software engineering has driven a transition from traditional rule-based systems to autonomous agentic systems capable of solving complex problems. However, systematic progress is…

Motivation: State-of-the-art biomedical named entity recognition (BioNER) systems often require handcrafted features specific to each entity type, such as genes, chemicals and diseases. Although recent studies explored using neural network…

信息检索 · 计算机科学 2018-10-09 Xuan Wang , Yu Zhang , Xiang Ren , Yuhao Zhang , Marinka Zitnik , Jingbo Shang , Curtis Langlotz , Jiawei Han

As LLM-based agents increasingly rely on external tools, it is important to evaluate their ability to sustain tool-grounded reasoning beyond familiar workflows and short-range interactions. We introduce AgentEscapeBench, an…

人工智能 · 计算机科学 2026-05-21 Zhengkang Guo , Yiyang Li , Lin Qiu , Xiaohua Wang , Jingwen Xv , Dongyu Ru , Xiaoyu Li , Xiaoqing Zheng , Xuezhi Cao , Xunliang Cai

The convergence of large language models and agents is catalyzing a new era of scientific discovery: Agentic Science. While the scientific method is inherently iterative, existing agent frameworks are predominantly static, narrowly scoped,…

As Multimodal Large Language Models (MLLMs) advance, multimodal agents show promise in real-world tasks like web navigation and embodied intelligence. However, due to limitations in a lack of external feedback, these agents struggle with…

计算与语言 · 计算机科学 2025-06-27 Tianyi Men , Zhuoran Jin , Pengfei Cao , Yubo Chen , Kang Liu , Jun Zhao

Modern AI agents, driven by advances in large foundation models, promise to enhance our productivity and transform our lives by augmenting our knowledge and capabilities. To achieve this vision, AI agents must effectively plan, perform…

Multimodal agents are making rapid progress on general computer-use tasks, yet existing benchmarks remain largely confined to browsers and basic desktop applications, falling short in professional software workflows that dominate real-world…

Drug discovery is a complex, multi-step pipeline that remains heavily dependent on manual, experience-driven operations; meanwhile, existing customized artificial intelligence tools are fragmented across web applications, desktop software,…

生物大分子 · 定量生物学 2026-03-03 Qihua Pan , Dong Xu , Qianwei Yang , Jenna Xinyi Yao , Sisi Yuan , Zexuan Zhu , Jianqiang Li , Junkai Ji

The development of artificial intelligence systems is transitioning from creating static, task-specific models to dynamic, agent-based systems capable of performing well in a wide range of applications. We propose an Interactive Agent…

As single-cell RNA sequencing datasets grow in adoption, scale, and complexity, data analysis remains a bottleneck for many research groups. Although frontier AI agents have improved dramatically at software engineering and general data…

基因组学 · 定量生物学 2026-02-11 Kenny Workman , Zhen Yang , Harihara Muralidharan , Aidan Abdulali , Hannah Le

Background: Pharmacokinetic evaluation is one of the key processes in drug discovery and development. However, current absorption, distribution, metabolism, excretion prediction models still have limited accuracy. Aim: This study aims to…

机器学习 · 计算机科学 2018-12-27 Zhuyifan Ye , Yilong Yang , Xiaoshan Li , Dongsheng Cao , Defang Ouyang

Data science agents promise to accelerate discovery and insight-generation by turning data into executable analyses and findings. Yet existing data science benchmarks fall short due to fragmented evaluation interfaces that make…

人工智能 · 计算机科学 2026-01-26 Fan Nie , Junlin Wang , Harper Hua , Federico Bianchi , Yongchan Kwon , Zhenting Qi , Owen Queen , Shang Zhu , James Zou

Agent-based modeling plays an essential role in gaining insights into biology, sociology, economics, and other fields. However, many existing agent-based simulation platforms are not suitable for large-scale studies due to the low…

分布式、并行与集群计算 · 计算机科学 2023-04-25 Lukas Breitwieser , Ahmad Hesam , Fons Rademakers , Juan Gómez Luna , Onur Mutlu

Endoscopic diagnosis is an iterative process in which clinicians progressively acquire, compare, and verify local visual evidence before reaching a conclusion. Current AI systems do not adequately support this process because fine-grained…

人工智能 · 计算机科学 2026-05-19 Yi Tang , Kai-Ni Wang , Yang Chen , Xiaopu He , Guangquan Zhou

Since the Transformer architecture emerged, language model development has grown, driven by their promising potential. Releasing these models into production requires properly understanding their behavior, particularly in sensitive domains…

计算与语言 · 计算机科学 2024-10-25 Andrea Posada , Daniel Rueckert , Felix Meissen , Philip Müller

Large language models are transitioning from generalpurpose knowledge engines to realworld problem solvers, yet optimizing them for deep search tasks remains challenging. The central bottleneck lies in the extreme sparsity of highquality…

Single-cell RNA sequencing (scRNA-seq) data analysis is crucial for biological research, as it enables the precise characterization of cellular heterogeneity. However, manual manipulation of various tools to achieve desired outcomes can be…

With the deep integration of artificial intelligence and interactive technology, Graphical User Interface (GUI) Agent, as the carrier connecting goal-oriented natural language and real-world devices, has received widespread attention from…

人工智能 · 计算机科学 2025-11-13 Leyang Yang , Ziwei Wang , Xiaoxuan Tang , Sheng Zhou , Dajun Chen , Wei Jiang , Yong Li

Clinical trials constitute a critical yet exceptionally challenging and costly stage of drug development (\$2.6B per drug), where protocols are encoded as complex natural language documents, motivating the use of AI systems beyond manual…

人工智能 · 计算机科学 2026-04-06 Sixue Xing , Kerui Wu , Xuanye Xia , Meng Jiang , Jintai Chen , Tianfan Fu

The number of biomedical research articles published has doubled in the past 20 years. Search engine based systems naturally center around searching, but researchers may not have a clear goal in mind, or the goal may be expressed in a query…

数字图书馆 · 计算机科学 2017-10-25 Jessica Perrie , Yanqi Hao , Zack Hayat , Recep Colak , Kelly Lyons , Shankar Vembu , Sam Molyneux
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