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While deep learning has exhibited remarkable predictive capabilities in various medical image tasks, its inherent black-box nature has hindered its widespread implementation in real-world healthcare settings. Our objective is to unveil the…

计算机视觉与模式识别 · 计算机科学 2025-04-08 Han Yuan , Lican Kang , Yong Li

Pseudoprogression (PsP) is an imitation of true tumor progression (TTP) in patients with glioblastoma multiform (GBM). Differentiating them is a challenging and time-consuming task for radiologists. Although deep neural networks can…

组织与器官 · 定量生物学 2019-02-27 Xiaoming Liu , Michael D. Chan , Xiaobo Zhou , Xiaohua Qian

Given the complexity of genetic risk prediction, there is a critical need for the development of novel methodologies that can effectively capture intricate genotype--phenotype relationships (e.g., nonlinear) while remaining statistically…

应用统计 · 统计学 2025-10-03 Heng Ge , Qing Lu

The significant portion of diabetic patients was affected due to major blindness caused by Diabetic retinopathy (DR). For diabetic retinopathy, lesion segmentation, and detection the comprehensive examination is delved into the deep…

人工智能 · 计算机科学 2024-11-20 Syed Mohd Faisal Malik , Md Tabrez Nafis , Mohd Abdul Ahad , Safdar Tanweer

The Gaussian process (GP) is a popular statistical technique for stochastic function approximation and uncertainty quantification from data. GPs have been adopted into the realm of machine learning in the last two decades because of their…

机器学习 · 统计学 2024-10-02 Marcus M. Noack , Hengrui Luo , Mark D. Risser

In recent years, the incidence of vision-threatening eye diseases has risen dramatically, necessitating scalable and accurate screening solutions. This paper presents a comprehensive study on deep learning architectures for the automated…

计算机视觉与模式识别 · 计算机科学 2025-12-12 Mohammad Sadegh Gholizadeh , Amir Arsalan Rezapour

The Gaussian Process with a deep kernel is an extension of the classic GP regression model and this extended model usually constructs a new kernel function by deploying deep learning techniques like long short-term memory networks. A…

计算金融 · 定量金融 2021-05-27 Yong Shi , Wei Dai , Wen Long , Bo Li

This study proposes a Transformer-based longitudinal modeling method to address challenges in clinical risk classification with heterogeneous Electronic Health Record (EHR) data, including irregular temporal patterns, large modality…

机器学习 · 计算机科学 2025-11-07 Anzhuo Xie , Wei-Chen Chang

This research paper addresses the critical challenge of diabetic retinopathy (DR), a severe complication of diabetes leading to potential blindness. The proposed methodology leverages transfer learning with convolutional neural networks…

图像与视频处理 · 电气工程与系统科学 2024-01-08 Manoj S H , Arya A Bosale

Automatic segmentation of multiple organs and tumors from 3D medical images such as magnetic resonance imaging (MRI) and computed tomography (CT) scans using deep learning methods can aid in diagnosing and treating cancer. However, organs…

图像与视频处理 · 电气工程与系统科学 2022-07-25 Hao Li , Yang Nan , Javier Del Ser , Guang Yang

Many diseases display heterogeneity in clinical features and their progression, indicative of the existence of disease subtypes. Extracting patterns of disease variable progression for subtypes has tremendous application in medicine, for…

定量方法 · 定量生物学 2020-08-04 Sanjukta Krishnagopal

As one kind of skin cancer, melanoma is very dangerous. Dermoscopy based early detection and recarbonization strategy is critical for melanoma therapy. However, well-trained dermatologists dominant the diagnostic accuracy. In order to solve…

计算机视觉与模式识别 · 计算机科学 2017-03-03 Hao Chang

Characterizing patient somatic mutations through next-generation sequencing technologies opens up possibilities for refining cancer subtypes. However, catalogues of mutations reveal that only a small fraction of the genes are altered…

计算工程、金融与科学 · 计算机科学 2017-01-05 Ali Burak Ünal , Öznur Taştan

Kernel method is a very powerful tool in machine learning. The trick of kernel has been effectively and extensively applied in many areas of machine learning, such as support vector machine (SVM) and kernel principal component analysis…

网络与互联网体系结构 · 计算机科学 2011-05-17 Shujie Hou , Robert C. Qiu

In this paper, we have proposed a new glaucoma classification approach that employs a wavelet neural network (WNN) on optimally enhanced retinal images features. To avoid tedious and error prone manual analysis of retinal images by…

计算机视觉与模式识别 · 计算机科学 2024-09-02 N. Krishna Santosh , Soubhagya Sankar Barpanda

Kernel-based subspace clustering, which addresses the nonlinear structures in data, is an evolving area of research. Despite noteworthy progressions, prevailing methodologies predominantly grapple with limitations relating to (i) the…

机器学习 · 计算机科学 2025-01-22 Kunpeng Xu , Lifei Chen , Shengrui Wang

The 7-point checklist (7PCL) is a widely used diagnostic tool in dermoscopy for identifying malignant melanoma by assigning point values to seven specific attributes. However, the traditional 7PCL is limited to distinguishing between…

计算机视觉与模式识别 · 计算机科学 2025-09-11 Yuheng Wang , Tianze Yu , Jiayue Cai , Sunil Kalia , Harvey Lui , Z. Jane Wang , Tim K. Lee

Diagnostic pathology, which is the basis and gold standard of cancer diagnosis, provides essential information on the prognosis of the disease and vital evidence for clinical treatment. Tumor region detection, subtype and grade…

图像与视频处理 · 电气工程与系统科学 2021-10-27 Jialun Wu , Haichuan Zhang , Zeyu Gao , Xinrui Bao , Tieliang Gong , Chunbao Wang , Chen Li

Glaucoma causes an irreversible damage to retinal nerve fibers which results in vision loss, if undetected in early stage. Therefore, diagnosis of glaucoma in its early stage may prevent further vision loss. In this paper, we propose a…

信号处理 · 电气工程与系统科学 2020-09-15 Shishir Maheshwari , Vivek Kanhangad , Ram Bilas Pachori

Lung cancer ranks as one of the leading causes of cancer diagnosis and is the foremost cause of cancer-related mortality worldwide. The early detection of lung nodules plays a pivotal role in improving outcomes for patients, as it enables…

计算机视觉与模式识别 · 计算机科学 2025-10-28 Jiasen Zhang , Mingrui Yang , Weihong Guo , Brian A. Xavier , Michael Bolen , Xiaojuan Li